Immunogenicity 335
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
IGDCC4
Transcript ID
uc002aou.1
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (1250 aa)
MARGD
1
AGRGR
6
GLLAL
11
TFCLL
16
AARGE
21
LLLPQ
26
ETTVE
31
LSCGV
36
GPLQV
41
ILGPE
46
QAAVL
51
NCSLG
56
AAAAG
61
PPTRV
66
TWSKD
71
GDTLL
76
EHDHL
81
HLLPN
86
GSLWL
91
SQPLA
96
PNGSD
101
ESVPE
106
AVGVI
111
EGNYS
116
CLAHG
121
PLGVL
126
ASQTA
131
VVKLA
136
TLADF
141
SLHPE
146
SQTVE
151
ENGTA
156
RFECH
161
IEGLP
166
APIIT
171
WEKDQ
176
VTLPE
181
EPRLI
186
VLPNG
191
VLQIL
196
DVQES
201
DAGPY
206
RCVAT
211
NSARQ
216
HFSQE
221
ALLSV
226
AHRGS
231
LASTR
236
GQDVV
241
IVAAP
246
ENTTV
251
VSGQS
256
VVMEC
261
VASAD
266
PTPFV
271
SWVRQ
276
DGKPI
281
STDVI
286
VLGRT
291
NLLIA
296
NAQPW
301
HSGVY
306
VCRAN
311
KPRTR
316
DFATA
321
AAELR
326
VLAAP
331
AITQA
336
PEALS
341
RTRAS
346
TARFV
351
CRASG
356
EPRPA
361
LRWLH
366
NGAPL
371
RPNGR
376
VKVQG
381
GGGSL
386
VITQI
391
GLQDA
396
GYYQC
401
VAENS
406
AGMAC
411
AAASL
416
AVVVR
421
EGLPS
426
APTRV
431
TATPL
436
SSSAV
441
LVAWE
446
RPEMH
451
SEQII
456
GFSLH
461
YQKAR
466
GMDNV
471
EYQFA
476
VNNDT
481
TELQV
486
RDLEP
491
NTDYE
496
FYVVA
501
YSQLG
506
ASRTS
511
TPALV
516
HTLDD
521
VPSAA
526
PQLSL
531
SSPNP
536
SDIRV
541
AWLPL
546
PPSLS
551
NGQVV
556
KYKIE
561
YGLGK
566
EDQIF
571
STEVR
576
GNETQ
581
LMLNS
586
LQPNK
591
VYRVR
596
ISAGT
601
AAGFG
606
APSQW
611
MHHRT
616
PSMHN
621
QSHVP
626
FAPAE
631
LKVQA
636
KMESL
641
VVSWQ
646
PPPHP
651
TQISG
656
YKLYW
661
REVGA
666
EEEAN
671
GDRLP
676
GGRGD
681
QAWDV
686
GPVRL
691
KKKVK
696
QYELT
701
QLVPG
706
RLYEV
711
KLVAF
716
NKHED
721
GYAAV
726
WKGKT
731
EKAPA
736
PDMPI
741
QRGPP
746
LPPAH
751
VHAES
756
NSSTS
761
IWLRW
766
KKPDF
771
TTVKI
776
VNYTV
781
RFSPW
786
GLRNA
791
SLVTY
796
YTSSG
801
EDILI
806
GGLKP
811
FTKYE
816
FAVQS
821
HGVDM
826
DGPFG
831
SVVER
836
STLPD
841
RPSTP
846
PSDLR
851
LSPLT
856
PSTVR
861
LHWCP
866
PTEPN
871
GEIVE
876
YLILY
881
SSNHT
886
QPEHQ
891
WTLLT
896
TQGNI
901
FSAEV
906
HGLES
911
DTRYF
916
FKMGA
921
RTEVG
926
PGPFS
931
RLQDV
936
ITLQE
941
KLSDS
946
LDMHS
951
VTGII
956
VGVCL
961
GLLCL
966
LACMC
971
AGLRR
976
SPHRE
981
SLPGL
986
SSTAT
991
PGNPA
996
LYSRA
1001
RLGPP
1006
SPPAA
1011
HELES
1016
LVHPH
1021
PQDWS
1026
PPPSD
1031
VEDRA
1036
EVHSL
1041
MGGGV
1046
SEGRS
1051
HSKRK
1056
ISWAQ
1061
PSGLS
1066
WAGSW
1071
AGCEL
1076
PQAGP
1081
RPALT
1086
RALLP
1091
PAGTG
1096
QTLLL
1101
QALVY
1106
DAIKG
1111
NGRKK
1116
SPPAC
1121
RNQVE
1126
AEVIV
1131
HSDFS
1136
ASNGN
1141
PDLHL
1146
QDLEP
1151
EDPLP
1156
PEAPD
1161
LISGV
1166
GDPGQ
1171
GAAWL
1176
DRELG
1181
GCELA
1186
APGPD
1191
RLTCL
1196
PEAAS
1201
ASCSY
1206
PDLQP
1211
GEVLE
1216
ETPGD
1221
SCQLK
1226
SPCPL
1231
GASPG
1236
LPRSP
1241
VSSSA
1246
Mutation Information
DNA mutation:
c.C2774T
Peptide Range:
913 ~ 937
Mut AA position:
925 (13 in Wild Type peptide)
Alignment
Wild Type:
"LESDTRYFFKMGARTEVGPGPFSRL
||||||||||||.||||||||||||
Mutant:
LESDTRYFFKMGVRTEVGPGPFSRL"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) IGDCC4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
LESDTRYFFKMGVRTEVGPGPFSRL
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT