Immunogenicity 338
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
KCNS2
Transcript ID
uc022azb.1
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (477 aa)
MTGQS
1
LWDVS
6
EANVE
11
DGEIR
16
INVGG
21
FKRRL
26
RSHTL
31
LRFPE
36
TRLGR
41
LLLCH
46
SREAI
51
LELCD
56
DYDDV
61
QREFY
66
FDRNP
71
ELFPY
76
VLHFY
81
HTGKL
86
HVMAE
91
LCVFS
96
FSQEI
101
EYWGI
106
NEFFI
111
DSCCS
116
YSYHG
121
RKVEP
126
EQEKW
131
DEQSD
136
QESTT
141
SSFDE
146
ILAFY
151
NDASK
156
FDGQP
161
LGNFR
166
RQLWL
171
ALDNP
176
GYSVL
181
SRVFS
186
ILSIL
191
VVMGS
196
IITMC
201
LNSLP
206
DFQIP
211
DSQGN
216
PGEDP
221
RFEIV
226
EHFGI
231
AWFTF
236
ELVAR
241
FAVAP
246
DFLKF
251
FKNAL
256
NLIDL
261
MSIVP
266
FYITL
271
VVNLV
276
VESTP
281
TLANL
286
GRVAQ
291
VLRLM
296
RIFRI
301
LKLAR
306
HSTGL
311
RSLGA
316
TLKYS
321
YKEVG
326
LLLLY
331
LSVGI
336
SIFSV
341
VAYTI
346
EKEEN
351
EGLAT
356
IPACW
361
WWATV
366
SMTTV
371
GYGDV
376
VPGTT
381
AGKLT
386
ASACI
391
LAGIL
396
VVVLP
401
ITLIF
406
NKFSH
411
FYRRQ
416
KQLES
421
AMRSC
426
DFGDG
431
MKEVP
436
SVNLR
441
DYYAH
446
KVKSL
451
MASLT
456
NMSRS
461
SPSEL
466
SLNDS
471
LR
476
Mutation Information
DNA mutation:
c.T1124A
Peptide Range:
363 ~ 387
Mut AA position:
375 (13 in Wild Type peptide)
Alignment
Wild Type:
"ACWWWATVSMTTVGYGDVVPGTTAG
||||||||||||.||||||||||||
Mutant:
ACWWWATVSMTTEGYGDVVPGTTAG"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) KCNS2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
ACWWWATVSMTTEGYGDVVPGTTAG
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT