Immunogenicity 3390

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
LRP1B
Transcript ID
uc010fnl.1
HLA INFO
B*38:01
TCR INFO

No TCR info found!

T cell Tumor cell B*38:01
sequence
Full length protein sequence (828 aa)
MTPLD
1
SRLQA
6
APAAA
11
AAAGP
16
KVPPS
21
SLQRR
26
LPYRA
31
TTMSE
36
FLLAL
41
LTLSG
46
LLPIA
51
RVLTV
56
GADRD
61
QQLCD
66
PGEFL
71
CHDHV
76
TCVSQ
81
SWLCD
86
GDPDC
91
PDDSD
96
ESLDT
101
SRTCQ
106
VDQFS
111
CGNGR
116
CIPRA
121
WLCDR
126
EDDCG
131
DQTDE
136
MASCE
141
FPTCE
146
PLTQF
151
VCKSG
156
RCISS
161
KWHCD
166
SDDDC
171
GDGSD
176
EVGCV
181
HSCFD
186
NQFRC
191
SSGRC
196
IPGHW
201
ACDGD
206
NDCGD
211
FSDEA
216
QINCT
221
KEEIH
226
SPAGC
231
NGNEF
236
QCHPD
241
GNCVP
246
DLWRC
251
DGEKD
256
CEDGS
261
DEKGC
266
NGTIR
271
LCDHK
276
TKFSC
281
WSTGR
286
CINKA
291
WVCDG
296
DIDCE
301
DQSDE
306
DDCDS
311
FLCGP
316
PKHPC
321
ANDTS
326
VCLQP
331
EKLCN
336
GKKDC
341
PDGSD
346
EGYLC
351
DECSL
356
NNGGC
361
SNHCS
366
VVPGR
371
GIVCS
376
CPEGL
381
QLNKD
386
NKTCE
391
IVDYC
396
SNHLK
401
CSQVC
406
EQHKH
411
TVKCS
416
CYEGW
421
KLDVD
426
GESCT
431
SVDPF
436
EAFII
441
FSIRH
446
EIRRI
451
DLHKR
456
DYSLL
461
VPGLR
466
NTIAL
471
DFHFN
476
QSLLY
481
WTDVV
486
EDRIY
491
RGKLS
496
ESGGV
501
SAIEV
506
VVEHG
511
LATPE
516
GLTVD
521
WIAGN
526
IYWID
531
SNLDQ
536
IEVAK
541
LDGSL
546
RTTLI
551
AGAME
556
HPRAI
561
ALDPR
566
YGILF
571
WTDWD
576
ANFPR
581
IESAS
586
MSGAG
591
RKTIY
596
KDMKT
601
GAWPN
606
GLTVD
611
HFEKR
616
IVWTD
621
ARSDA
626
IYSAL
631
YDGTN
636
MIEII
641
RGHEY
646
LSHPF
651
AVSLY
656
GSEVY
661
WTDWR
666
TNTLS
671
KANKW
676
TGQNV
681
SVIQK
686
TSAQP
691
FDLQI
696
YHPSR
701
QPQAP
706
NPCAA
711
NDGKG
716
PCSHM
721
CLINH
726
NRSAA
731
CACPH
736
LMKLS
741
SDKKT
746
CYEMK
751
KFLLY
756
ARRSE
761
IRGVD
766
IDNPY
771
FNFIT
776
AFTVP
781
DIDDV
786
TVIDF
791
DASEE
796
RLYWT
801
DIKTQ
806
TIKRA
811
FINGT
816
GLETV
821
ISR
826
Mutation Information
DNA mutation:
None
Peptide Range:
562 ~ 586
Mut AA position:
574 (13 in Wild Type peptide)
Alignment
Wild Type:
"PRAIALDPRYGILFWTDWDANFPRI
||||||||||||.||||||||||||
Mutant:
PRAIALDPRYGIFFWTDWDANFPRI"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) LRP1B

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay