Immunogenicity 3394
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CASP8
Transcript ID
uc010ftf.2
HLA INFO
C*07:01
TCR INFO
No TCR info found!
Full length protein sequence (395 aa)
MDFSR
1
NLYDI
6
GEQLD
11
SEDLA
16
SLKFL
21
SLDYI
26
PQRKQ
31
EPIKD
36
ALMLF
41
QRLQE
46
KRMLE
51
ESNLS
56
FLKEL
61
LFRIN
66
RLDLL
71
ITYLN
76
TRKEE
81
MEREL
86
QTPGR
91
AQISA
96
YRVML
101
YQISE
106
EVSRS
111
ELRSF
116
KFLLQ
121
EEISK
126
CKLDD
131
DMNLL
136
DIFIE
141
MEKRV
146
ILGEG
151
KLDIL
156
KRVCA
161
QINKS
166
LLKII
171
NDYEE
176
FSKGA
181
LTTTF
186
EELHF
191
EIKPH
196
DDCTV
201
EQIYE
206
ILKIY
211
QLMDH
216
SNMDC
221
FICCI
226
LSHGD
231
KGIIY
236
GTDGQ
241
EAPIY
246
ELTSQ
251
FTGLK
256
CPSLA
261
GKPKV
266
FFIQA
271
CQGDN
276
YQKGI
281
PVETD
286
SEEQP
291
YLEMD
296
LSSPQ
301
TRYIP
306
DEADF
311
LLGMA
316
TVNNC
321
VSYRN
326
PAEGT
331
WYIQS
336
LCQSL
341
RERCP
346
RGDDI
351
LTILT
356
EVNYE
361
VSNKD
366
DKKNM
371
GKQMP
376
QPTFT
381
LRKKL
386
VFPSD
391
Mutation Information
DNA mutation:
None
Peptide Range:
55 ~ 79
Mut AA position:
67 (13 in Wild Type peptide)
Alignment
Wild Type:
"EESNLSFLKELLFRINRLDLLITYL
||||||||||||.||||||||||||
Mutant:
EESNLSFLKELLVRINRLDLLITYL"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) CASP8
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay