Immunogenicity 3415
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SPHKAP
Transcript ID
uc002vpp.2
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1671 aa)
MDGNS
1
LLSVP
6
SNLES
11
SRMYD
16
VLEPQ
21
QGRGC
26
GSSGS
31
GPGNS
36
ITACK
41
KVLRS
46
NSLLE
51
STDYW
56
LQNQR
61
MPCQI
66
GFVED
71
KSENC
76
ASVCF
81
VNLDV
86
NKDEC
91
STEHL
96
QQKLV
101
NVSPD
106
LPKLI
111
SSMNV
116
QQPKE
121
NEIVV
126
LSGLA
131
SGNLQ
136
ADFEV
141
SQCPW
146
LPDIC
151
LVQCA
156
RGNRP
161
NSTNC
166
IIFEI
171
NKFLI
176
GLELV
181
QERQL
186
HLETN
191
ILKLE
196
DDTNC
201
SLSSI
206
EEDFL
211
TASEH
216
LEEES
221
EVDES
226
RNDYE
231
NINVS
236
ANVLE
241
SKQLK
246
GATQV
251
EWNCN
256
KEKWL
261
YALED
266
KYINK
271
YPTPL
276
IKTER
281
SPENL
286
TKNTA
291
LQSLD
296
PSAKP
301
SQWKR
306
EAVGN
311
GRQAT
316
HYYHS
321
EAFKG
326
QMEKS
331
QALYI
336
PKDAY
341
FSMMD
346
KDVPS
351
ACAVA
356
EQRSN
361
LNPGD
366
HEDTR
371
NALPP
376
RQDGE
381
VTTGK
386
YATNL
391
AESVL
396
QDAFI
401
RLSQS
406
QSTLP
411
QESAV
416
SVSVG
421
SSLLP
426
SCYST
431
KDTVV
436
SRSWN
441
ELPKI
446
VVVQS
451
PDGSD
456
AAPQP
461
GISSW
466
PEMEV
471
SVETS
476
SILSG
481
ENSSR
486
QPQSA
491
LEVAL
496
ACAAT
501
VIGTI
506
SSPQA
511
TERLK
516
MEQVV
521
SNFPP
526
GSSGA
531
LQTQA
536
PQGLK
541
EPSIN
546
EYSFP
551
SALCG
556
MTQVA
561
SAVAV
566
CGLGE
571
REEVT
576
CSVAP
581
SGSLP
586
PAAEA
591
SEAMP
596
PLCGL
601
ASMEL
606
GKEAI
611
AKGLL
616
KEAAL
621
VLTRP
626
NTYSS
631
IGDFL
636
DSMNR
641
RIMET
646
ASKSQ
651
TLCSE
656
NVVRN
661
ELAHT
666
LSNVI
671
LRHSI
676
DEVHH
681
KNMII
686
DPNDN
691
RHSSE
696
ILDTL
701
MESTN
706
QLLLD
711
VICFT
716
FKKMS
721
HIVRL
726
GECPA
731
VLSKE
736
TIRRR
741
ETEPS
746
CQPSD
751
PGASQ
756
AWTKA
761
TESSS
766
SSPLS
771
NSHNT
776
SLVIN
781
NLVDG
786
MYSKQ
791
DKGGV
796
RPGLF
801
KNPTL
806
QSQLS
811
RSHRV
816
PDSST
821
ATTSS
826
KEIYL
831
KGIAG
836
EDTKS
841
PHHSE
846
NECRA
851
SSEGQ
856
RSPTV
861
SQSRS
866
GSQEA
871
EESIH
876
PNTQE
881
KYNCA
886
TSRIN
891
EVQVN
896
LSLLG
901
DDLLL
906
PAQST
911
LQTKH
916
PDIYC
921
ITDFA
926
EELAD
931
TVVSM
936
ATEIA
941
AICLD
946
NSSGK
951
QPWFC
956
AWKRG
961
SEFLM
966
TPNVP
971
CRSLK
976
RKKES
981
QGSGT
986
AVRKH
991
KPPRL
996
SEIKR
1001
KTDEH
1006
PELKE
1011
KLMNR
1016
VVDES
1021
MNLED
1026
VPDSV
1031
NLFAN
1036
EVAAK
1041
IMNLT
1046
EFSMV
1051
DGMWQ
1056
AQGYP
1061
RNRLL
1066
SGDRW
1071
SRLKA
1076
SSCES
1081
IPEED
1086
SEARA
1091
YVNSL
1096
GLMST
1101
LSQPV
1106
SRASS
1111
VSKQS
1116
SCESI
1121
TDEFS
1126
RFMVN
1131
QMENE
1136
GRGFE
1141
LLLDY
1146
YAGKN
1151
ASSIL
1156
NSAMQ
1161
QACRK
1166
SDHLS
1171
VRPSC
1176
PSKQS
1181
STESI
1186
TEEFY
1191
RYMLR
1196
DIERD
1201
SRESA
1206
SSRRS
1211
SQDWT
1216
AGLLS
1221
PSLRS
1226
PVCHR
1231
QSSMP
1236
DSRSP
1241
CSRLT
1246
VNVPI
1251
KANSL
1256
DGFAQ
1261
NCPQD
1266
FLSVQ
1271
PVSSA
1276
SSSGL
1281
CKSDS
1286
CLYRR
1291
GGTDH
1296
ITNML
1301
IHETW
1306
ASSIE
1311
ALMRK
1316
NKIIV
1321
DDAEE
1326
ADTEP
1331
VSGGS
1336
PSQAE
1341
KCANR
1346
LAASR
1351
MCSGP
1356
TLLVQ
1361
ESLDC
1366
PRKDS
1371
VTECK
1376
QPPVS
1381
SLSKT
1386
ASLTN
1391
HSPLD
1396
SKKET
1401
SSCQD
1406
PVPIN
1411
HKRRS
1416
LCSRE
1421
VPLIQ
1426
IETDQ
1431
REACA
1436
GEPEP
1441
FLSKS
1446
SLLEE
1451
AEGHS
1456
NDKNI
1461
PDVVR
1466
GGDTA
1471
VSACQ
1476
IHSDS
1481
LDTRD
1486
VPEAE
1491
ASTEA
1496
RAPDE
1501
APNPP
1506
SSSEE
1511
STGSW
1516
TQLAN
1521
EEDNP
1526
DDTSS
1531
FLQLS
1536
ERSMS
1541
ELVEE
1546
KKILK
1551
GQSES
1556
TEAPA
1561
SGPPT
1566
GTASP
1571
QRSLL
1576
VINFD
1581
LEPEC
1586
PDAEL
1591
RATLQ
1596
WIAAS
1601
ELGIP
1606
TIYFK
1611
KSQEN
1616
RIEKF
1621
LDVVQ
1626
LVHRK
1631
SWKVG
1636
DIFHA
1641
VVQYC
1646
KMHEE
1651
QKDGR
1656
LSLFD
1661
WLLEL
1666
G
1671
Mutation Information
DNA mutation:
None
Peptide Range:
1153 ~ 1177
Mut AA position:
1165 (13 in Wild Type peptide)
Alignment
Wild Type:
"GKNASSILNSAMQQACRKSDHLSVR
||||||||||||.||||||||||||
Mutant:
GKNASSILNSAMKQACRKSDHLSVR"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) SPHKAP
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay