Immunogenicity 3465

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
GDF5OS
Transcript ID
uc002xcj.3
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (331 aa)
MEQIE
1
LGTQG
6
PLEGT
11
GMRLE
16
ECRKG
21
LLGCA
26
TQEDR
31
GPVLL
36
PAATR
41
LHDHV
46
LILLI
51
HHVVG
56
RVNEE
61
DADGT
66
QPRGH
71
TAGGW
76
CGLGV
81
HGVHQ
86
GLDDC
91
MIRGL
96
QVGAQ
101
WELAQ
106
PLAVE
111
SLVLK
116
GCDDP
121
VVPAH
126
VLEVD
131
MQCLP
136
TAASL
141
KVLAG
146
SLALA
151
SGQWG
156
PPFSP
161
LAEQV
166
LIHGL
171
IVLAR
176
AGLNL
181
IKEQV
186
PFLGA
191
AKHQE
196
QGLLV
201
DLPGG
206
AVEAQ
211
ATEVH
216
GPAPF
221
PGLQL
226
QAQLG
231
RVLKV
236
SEELP
241
DVEHL
246
PARSV
251
QAWHG
256
AHIQQ
261
GGRLP
266
AAGAA
271
GQLQL
276
GSPPA
281
SGGRW
286
LGRVR
291
GLLPQ
296
DPQLG
301
PQQPI
306
LLQGT
311
NVKHV
316
PLLPD
321
HGTSV
326
I
331
Mutation Information
DNA mutation:
None
Peptide Range:
268 ~ 292
Mut AA position:
280 (13 in Wild Type peptide)
Alignment
Wild Type:
"RLPAAGAAGQLQLGSPPASGGRWLG
||||||||||||.||||||||||||
Mutant:
RLPAAGAAGQLQPGSPPASGGRWLG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GDF5OS

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay