Immunogenicity 347
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
TPR
Transcript ID
uc010pop.2
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (2363 aa)
MAAVL
1
QQVLE
6
RTELN
11
KLPKS
16
VQNKL
21
EKFLA
26
DQQSE
31
IDGLK
36
GRHEK
41
FKVES
46
EQQYF
51
EIEKR
56
LSHSQ
61
ERLVN
66
ETREC
71
QSLRL
76
ELEKL
81
NNQLK
86
ALTEK
91
NKELE
96
IAQDR
101
NIAIQ
106
SQFTR
111
TKEEL
116
EAEKR
121
DLIRT
126
NERLS
131
QELEY
136
LTEDV
141
KRLNE
146
KLKES
151
NTTKG
156
ELQLK
161
LDELQ
166
ASDVS
171
VKYRE
176
KRLEQ
181
EKELL
186
HSQNT
191
WLNTE
196
LKTKT
201
DELLA
206
LGREK
211
GNEIL
216
ELKCN
221
LENKK
226
EEVSR
231
LEEQM
236
NGLKT
241
SNEHL
246
QKHVE
251
DLLTK
256
LKEAK
261
EQQAS
266
MEEKF
271
HNELN
276
AHIKL
281
SNLYK
286
SAADD
291
SEAKS
296
NELTR
301
AVEEL
306
HKLLK
311
EAGEA
316
NKAIQ
321
DHLLE
326
VEQSK
331
DQMEK
336
EMLEK
341
IGRLE
346
KELEN
351
ANDLL
356
SATKR
361
KGAIL
366
SEEEL
371
AAMSP
376
TAAAV
381
AKIVK
386
PGMKL
391
TELYN
396
AYVET
401
QDQLL
406
LEKLE
411
NKRIN
416
KYLDE
421
IVKEV
426
EAKAP
431
ILKRQ
436
REEYE
441
RAQKA
446
VASLS
451
VKLEQ
456
AMKEI
461
QRLQE
466
DTDKA
471
NKQSS
476
VLERD
481
NRRME
486
IQVKD
491
LSQQI
496
RVLLM
501
ELEEA
506
RGNHV
511
IRDEE
516
VSSAD
521
ISSSS
526
EVISQ
531
HLVSY
536
RNIEE
541
LQQQN
546
QRLLV
551
ALREL
556
GETRE
561
REEQE
566
TTSSK
571
ITELQ
576
LKLES
581
ALTEL
586
EQLRK
591
SRQHQ
596
MQLVD
601
SIVRQ
606
RDMYR
611
ILLSQ
616
TTGVA
621
IPLHA
626
SSLDD
631
VSLAS
636
TPKRP
641
STSQT
646
VSTPA
651
PVPVI
656
ESTEA
661
IEAKA
666
ALKQL
671
QEIFE
676
NYKKE
681
KAENE
686
KIQNE
691
QLEKL
696
QEQVT
701
DLRSQ
706
NTKIS
711
TQLDF
716
ASKRY
721
EMLQD
726
NVEGY
731
RREIT
736
SLHER
741
NQKLT
746
ATTQK
751
QEQII
756
NTMTQ
761
DLRGA
766
NEKLA
771
VAEVR
776
AENLK
781
KEKEM
786
LKLSE
791
VRLSQ
796
QRESL
801
LAEQR
806
GQNLL
811
LTNLQ
816
TIQGI
821
LERSE
826
TETKQ
831
RLSSQ
836
IEKLE
841
HEISH
846
LKKKL
851
ENEVE
856
QRHTL
861
TRNLD
866
VQLLD
871
TKRQL
876
DTETN
881
LHLNT
886
KELLK
891
NAQKE
896
IATLK
901
QHLSN
906
MEVQV
911
ASQSS
916
QRTGK
921
GQPSN
926
KEDVD
931
DLVSQ
936
LRQTE
941
EQVND
946
LKERL
951
KTSTS
956
NVEQY
961
QAMVT
966
SLEES
971
LNKEK
976
QVTEE
981
VRKNI
986
EVRLK
991
ESAEF
996
QTQLE
1001
KKLME
1006
VEKEK
1011
QELQD
1016
DKRRA
1021
IESME
1026
QQLSE
1031
LKKTL
1036
SSVQN
1041
EVQEA
1046
LQRAS
1051
TALSN
1056
EQQAR
1061
RDCQE
1066
QAKIA
1071
VEAQN
1076
KYERE
1081
LMLHA
1086
ADVEA
1091
LQAAK
1096
EQVSK
1101
MASVR
1106
QHLEE
1111
TTQKA
1116
ESQLL
1121
ECKAS
1126
WEERE
1131
RMLKD
1136
EVSKC
1141
VCRCE
1146
DLEKQ
1151
NRLLH
1156
DQIEK
1161
LSDKV
1166
VASVK
1171
EGVQG
1176
PLNVS
1181
LSEEG
1186
KSQEQ
1191
ILEIL
1196
RFIRR
1201
EKEIA
1206
ETRFE
1211
VAQVE
1216
SLRYR
1221
QRVEL
1226
LEREL
1231
QELQD
1236
SLNAE
1241
REKVQ
1246
VTAKT
1251
MAQHE
1256
ELMKK
1261
TETMN
1266
VVMET
1271
NKMLR
1276
EEKER
1281
LEQDL
1286
QQMQA
1291
KVRKL
1296
ELDIL
1301
PLQEA
1306
NAELS
1311
EKSGM
1316
LQAEK
1321
KLLEE
1326
DVKRW
1331
KARNQ
1336
HLVSQ
1341
QKDPD
1346
TEEYR
1351
KLLSE
1356
KEVHT
1361
KRIQQ
1366
LTEEI
1371
GRLKA
1376
EIARS
1381
NASLT
1386
NNQNL
1391
IQSLK
1396
EDLNK
1401
VRTEK
1406
ETIQK
1411
DLDAK
1416
IIDIQ
1421
EKVKT
1426
ITQVK
1431
KIGRR
1436
YKTQY
1441
EELKA
1446
QQDKV
1451
METSA
1456
QSSGD
1461
HQEQH
1466
VSVQE
1471
MQELK
1476
ETLNQ
1481
AETKS
1486
KSLES
1491
QVENL
1496
QKTLS
1501
EKETE
1506
ARNLQ
1511
EQTVQ
1516
LQSEL
1521
SRLRQ
1526
DLQDR
1531
TTQEE
1536
QLRQQ
1541
ITEKE
1546
EKTRK
1551
AIVAA
1556
KSKIA
1561
HLAGV
1566
KDQLT
1571
KENEE
1576
LKQRN
1581
GALDQ
1586
QKDEL
1591
DVRIT
1596
ALKSQ
1601
YEGRI
1606
SRLER
1611
ELREH
1616
QERHL
1621
EQRDE
1626
PQEPS
1631
NKVPE
1636
QQRQI
1641
TLKTT
1646
PASGE
1651
RGIAS
1656
TSDPP
1661
TANIK
1666
PTPVV
1671
STPSK
1676
VTAAA
1681
MAGNK
1686
STPRA
1691
SIRPM
1696
VTPAT
1701
VTNPT
1706
TTPTA
1711
TVMPT
1716
TQVES
1721
QEAMQ
1726
SEGPV
1731
EHVPV
1736
FGSTS
1741
GSVRS
1746
TSPNV
1751
QPSIS
1756
QPILT
1761
VQQQT
1766
QATAF
1771
VQPTQ
1776
QSHPQ
1781
IEPAN
1786
QELSS
1791
NIVEV
1796
VQSSP
1801
VERPS
1806
TSTAV
1811
FGTVS
1816
ATPSS
1821
SLPKR
1826
TREEE
1831
EDSTI
1836
EASDQ
1841
VSDDT
1846
VEMPL
1851
PKKLK
1856
SVTPV
1861
GTEEE
1866
VMAEE
1871
STDGE
1876
VETQV
1881
YNQDS
1886
QDSIG
1891
EGVTQ
1896
GDYTP
1901
MEDSE
1906
ETSQS
1911
LQIDL
1916
GPLQS
1921
DQQTT
1926
TSSQD
1931
GQGKG
1936
DDVIV
1941
IDSDD
1946
EEEDD
1951
DENDG
1956
EHEDY
1961
EEDEE
1966
DDDDD
1971
EDDTG
1976
MGDEG
1981
EDSNE
1986
GTGSA
1991
DGNDG
1996
YEADD
2001
AEGGD
2006
GTDPG
2011
TETEE
2016
SMGGG
2021
EGNHR
2026
AADSQ
2031
NSGEG
2036
NTGAA
2041
ESSFS
2046
QEVSR
2051
EQQPS
2056
SASER
2061
QAPRA
2066
PQSPR
2071
RPPHP
2076
LPPRL
2081
TIHAP
2086
PQELG
2091
PPVQR
2096
IQMTR
2101
RQSVG
2106
RGLQL
2111
TPGIG
2116
GMQQH
2121
FFDDE
2126
DRTVP
2131
STPTL
2136
VVPHR
2141
TDGFA
2146
EAIHS
2151
PQVAG
2156
VPRFR
2161
FGPPE
2166
DMPQT
2171
SSSHS
2176
DLGQL
2181
ASQGG
2186
LGMYE
2191
TPLFL
2196
AHEEE
2201
SGGRS
2206
VPTTP
2211
LQVAA
2216
PVTVF
2221
TESTT
2226
SDASE
2231
HASQS
2236
VPMVT
2241
TSTGT
2246
LSTTN
2251
ETATG
2256
DDGDE
2261
VFVEA
2266
ESEGI
2271
SSEAG
2276
LEIDS
2281
QQEEE
2286
PVQAS
2291
DESDL
2296
PSTSQ
2301
DPPSS
2306
SSVDT
2311
SSSQP
2316
KPFRR
2321
VRLQT
2326
TLRQG
2331
VRGRQ
2336
FNRQR
2341
GVSHA
2346
MGGRG
2351
GINRG
2356
NIN
2361
Mutation Information
DNA mutation:
c.T1748C
Peptide Range:
495 ~ 519
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"DLSQQIRVLLMELEEARGNHVIRDE
||||||||||||.||||||||||||
Mutant:
DLSQQIRVLLMEPEEARGNHVIRDE"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) TPR
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
DLSQQIRVLLMEPEEARGNHVIRDE
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT