Immunogenicity 3470

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
SCAND1
Transcript ID
uc002xeo.3
HLA INFO
B*44:03
TCR INFO

No TCR info found!

T cell Tumor cell B*44:03
sequence
Full length protein sequence (179 aa)
MAATE
1
PILAA
6
TGSPA
11
AVPPE
16
KLEGA
21
GSSSA
26
PERNC
31
VGSSL
36
PEASP
41
PAPEP
46
SSPNA
51
AVPEA
56
IPTPR
61
AAASA
66
ALELP
71
LGPAP
76
VSVAP
81
QAEAE
86
ARSTP
91
GPAGS
96
RLGPE
101
TFRQR
106
FRQFR
111
YQDAA
116
GPREA
121
FRQLR
126
ELSRQ
131
WLRPD
136
IRTKE
141
QIVEM
146
LVQEQ
151
LLAIL
156
PEAAR
161
ARRIR
166
RRTDV
171
RITG
176
Mutation Information
DNA mutation:
None
Peptide Range:
36 ~ 60
Mut AA position:
48 (13 in Wild Type peptide)
Alignment
Wild Type:
"VGSSLPEASPPAPEPSSPNAAVPEA
||||||||||||.||||||||||||
Mutant:
VGSSLPEASPPALEPSSPNAAVPEA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SCAND1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay