Immunogenicity 3479

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
KCNB1
Transcript ID
uc002xus.1
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (858 aa)
MPAGM
1
TKHGS
6
RSTSS
11
LPPEP
16
MEIVR
21
SKACS
26
RRVRL
31
NVGGL
36
AHEVL
41
WRTLD
46
RLPRT
51
RLGKL
56
RDCNT
61
HDSLL
66
EVCDD
71
YSLDD
76
NEYFF
81
DRHPG
86
AFTSI
91
LNFYR
96
TGRLH
101
MMEEM
106
CALSF
111
SQELD
116
YWGID
121
EIYLE
126
SCCQA
131
RYHQK
136
KEQMN
141
EELKR
146
EAETL
151
REREG
156
EEFDN
161
TCCAE
166
KRKKL
171
WDLLE
176
KPNSS
181
VAAKI
186
LAIIS
191
IMFIV
196
LSTIA
201
LSLNT
206
LPELQ
211
SLDEF
216
GQSTD
221
NPQLA
226
HVEAV
231
CIAWF
236
TMEYL
241
LRFLS
246
SPKKW
251
KFFKG
256
PLNAI
261
DLLAI
266
LPYYV
271
TIFLT
276
ESNKS
281
VLQFQ
286
NVRRV
291
VQIFR
296
IMRIL
301
RILKL
306
ARHST
311
GLQSL
316
GFTLR
321
RSYNE
326
LGLLI
331
LFLAM
336
GIMIF
341
SSLVF
346
FAEKD
351
EDDTK
356
FKSIP
361
ASFWW
366
ATITM
371
TTVGY
376
GDIYP
381
KTLLG
386
KIVGG
391
LCCIA
396
GVLVI
401
ALPIP
406
IIVNN
411
FSEFY
416
KEQKR
421
QEKAI
426
KRREA
431
LERAK
436
RNGSI
441
VSMNM
446
KDAFA
451
RSIEM
456
MDIVV
461
EKNGE
466
NMGKK
471
DKVQD
476
NHLSP
481
NKWKW
486
TKRTL
491
SETSS
496
SKSFE
501
TKEQG
506
SPEKA
511
RSSSS
516
PQHLN
521
VQQLE
526
DMYNK
531
MAKTQ
536
SQPIL
541
NTKES
546
AAQSK
551
PKEEL
556
EMESI
561
PSPVA
566
PLPTR
571
TEGVI
576
DMRSM
581
SSIDS
586
FISCA
591
TDFPE
596
ATRFS
601
HSPLT
606
SLPSK
611
TGGST
616
APEVG
621
WRGAL
626
GASGG
631
RFVEA
636
NPSPD
641
ASQHS
646
SFFIE
651
SPKSS
656
MKTNN
661
PLKLR
666
ALKVN
671
FMEGD
676
PSPLL
681
PVLGM
686
YHDPL
691
RNRGS
696
AAAAV
701
AGLEC
706
ATLLD
711
KAVLS
716
PESSI
721
YTTAS
726
AKTPP
731
RSPEK
736
HTAIA
741
FNFEA
746
GVHQY
751
IDADT
756
DDEGQ
761
LLYSV
766
DSSPP
771
KSLPG
776
STSPK
781
FSTGT
786
RSEKN
791
HFESS
796
PLPTS
801
PKFLR
806
QNCIY
811
STEAL
816
TGKGP
821
SGQEK
826
CKLEN
831
HISPD
836
VRVLP
841
GGGAH
846
GSTRD
851
QSI
856
Mutation Information
DNA mutation:
None
Peptide Range:
631 ~ 655
Mut AA position:
643 (13 in Wild Type peptide)
Alignment
Wild Type:
"GASGGRFVEANPSPDASQHSSFFIE
||||||||||||.||||||||||||
Mutant:
GASGGRFVEANPRPDASQHSSFFIE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) KCNB1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay