Immunogenicity 3529
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TXNRD2
Transcript ID
uc002zqr.1
HLA INFO
C*07:02
TCR INFO
No TCR info found!
Full length protein sequence (521 aa)
MAAMA
1
VALRG
6
LGGRF
11
RWRTQ
16
AVAGG
21
VRGAA
26
RGAAG
31
QRDYD
36
LLVVG
41
GGSGG
46
LACAK
51
EAAQL
56
GRKVA
61
VVDYV
66
EPSPQ
71
GTRWG
76
LGGTC
81
VNVGC
86
IPKKL
91
MHQAA
96
LLGGL
101
IQDAP
106
NYGWE
111
VAQPV
116
PHDWR
121
KMAEA
126
VQNHV
131
KSLNW
136
GHRVQ
141
LQDRK
146
VKYFN
151
IKASF
156
VDEHT
161
VCGVA
166
KGGKE
171
ILLSA
176
DHIII
181
ATGGR
186
PRYPT
191
HIEGA
196
LEYGI
201
TSDDI
206
FWLKE
211
SPGKT
216
LVVGA
221
SYVAL
226
ECAGF
231
LTGIG
236
LDTTI
241
MMRSI
246
PLRGF
251
DQQMS
256
SMVIE
261
HMASH
266
GTRFL
271
RGCAP
276
SRVRR
281
LPDGQ
286
LQVTW
291
EDSTT
296
GKEDT
301
GTFDT
306
VLWAI
311
GRVPD
316
TRSLN
321
LEKAG
326
VDTSP
331
DTQKI
336
LVDSR
341
EATSV
346
PHIYA
351
IGDVV
356
EGRPE
361
LTPIA
366
IMAGR
371
LLVQR
376
LFGGS
381
SDLMD
386
YDNVP
391
TTVFT
396
PLEYG
401
CVGLS
406
EEEAV
411
ARHGQ
416
EHVEV
421
YHAHY
426
KPLEF
431
TVAGR
436
DASQC
441
YVKMV
446
CLREP
451
PQLVL
456
GLHFL
461
GPNAG
466
EVTQG
471
FALGI
476
KCGAS
481
YAQVM
486
RTVGI
491
HPTCS
496
EEVVK
501
LRISK
506
RSGLD
511
PTVTG
516
C
521
Mutation Information
DNA mutation:
None
Peptide Range:
343 ~ 367
Mut AA position:
355 (13 in Wild Type peptide)
Alignment
Wild Type:
"DSREATSVPHIYAIGDVVEGRPELT
||||||||||||.||||||||||||
Mutant:
DSREATSVPHIYTIGDVVEGRPELT"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) TXNRD2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay