Immunogenicity 3547

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
APOL5
Transcript ID
uc003aof.3
HLA INFO
DRB*15:02
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:02
sequence
Full length protein sequence (433 aa)
MPCGK
1
QGNLQ
6
VPGSK
11
VLPGL
16
GEGCK
21
EMWLR
26
KVIYG
31
GEVWG
36
KSPEP
41
EFPSL
46
VNLCQ
51
SWKIN
56
NLMST
61
VHSDE
66
AGMLS
71
YFLFE
76
ELMRC
81
DKDSM
86
PDGNL
91
SEEEK
96
LFLSY
101
FPLHK
106
FELEQ
111
NIKEL
116
NTLAD
121
QVDTT
126
HELLT
131
KTSLV
136
ASSSG
141
AVSGV
146
MNILG
151
LALAP
156
VTAGG
161
SLMLS
166
ATGTG
171
LGAAA
176
AITNI
181
VTNVL
186
ENRSN
191
SAARD
196
KASRL
201
GPLTT
206
SHEAF
211
GGINW
216
SEIEA
221
AGFCV
226
NKCVK
231
AIQGI
236
KDLHA
241
YQMAK
246
SNSGF
251
MAMVK
256
NFVAK
261
RHIPF
266
WTARG
271
VQRAF
276
EGTTL
281
AMTNG
286
AWVMG
291
AAGAG
296
FLLMK
301
DMSSF
306
LQSWK
311
HLEDG
316
ARTET
321
AEELR
326
ALAKK
331
LEQEL
336
DRLTQ
341
HHRHL
346
PQKAS
351
QTCSS
356
SRGRA
361
VRGSR
366
VVKPE
371
GSRSP
376
LPWPV
381
VEHQP
386
RLGPG
391
VALRT
396
PKRTV
401
SAPRM
406
LGHQP
411
APPAP
416
ARKGR
421
QAPGR
426
HRQ
431
Mutation Information
DNA mutation:
None
Peptide Range:
335 ~ 359
Mut AA position:
347 (13 in Wild Type peptide)
Alignment
Wild Type:
"KLEQELDRLTQHHRHLPQKASQTCS
||||||||||||.||||||||||||
Mutant:
KLEQELDRLTQHPRHLPQKASQTCS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) APOL5

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay