Immunogenicity 355
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
IMPG2
Transcript ID
uc003duq.2
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (1241 aa)
MIMFP
1
LFGKI
6
SLGIL
11
IFVLI
16
EGDFP
21
SLTAQ
26
TYLSI
31
EEIQE
36
PKSAV
41
SFLLP
46
EESTD
51
LSLAT
56
KKKQP
61
LDRRE
66
TERQW
71
LIRRR
76
RSILF
81
PNGVK
86
ICPDE
91
SVAEA
96
VANHV
101
KYFKV
106
RVCQE
111
AVWEA
116
FRTFW
121
DRLPG
126
REEYH
131
YWMNL
136
CEDGV
141
TSIFE
146
MGTNF
151
SESVE
156
HRSLI
161
MKKLT
166
YAKET
171
VSSSE
176
LSSPV
181
PVGDT
186
STLGD
191
TTLSV
196
PHPEV
201
DAYEG
206
ASESS
211
LERPE
216
ESISN
221
EIENV
226
IEEAT
231
KPAGE
236
QIAEF
241
SIHLL
246
GKQYR
251
EELQD
256
SSSFH
261
HQHLE
266
EEFIS
271
EVENA
276
FTGLP
281
GYKEI
286
RVLEF
291
RSPKE
296
NDSGV
301
DVYYA
306
VTFNG
311
EAISN
316
TTWDL
321
ISLHS
326
NKVEN
331
HGLVE
336
LDDKP
341
TVVYT
346
ISNFR
351
DYIAE
356
TLQQN
361
FLLGN
366
SSLNP
371
DPDSL
376
QLINV
381
RGVLR
386
HQTED
391
LVWNT
396
QSSSL
401
QATPS
406
SILDN
411
TFQAA
416
WPSAD
421
ESITS
426
SIPPL
431
DFSSG
436
PPSAT
441
GRELW
446
SESPL
451
GDLVS
456
THKLA
461
FPSKM
466
GLSSS
471
PEVLE
476
VSSLT
481
LHSVT
486
PAVLQ
491
TGLPV
496
ASEER
501
TSGSH
506
LVEDG
511
LANVE
516
ESEDF
521
LSIDS
526
LPSSS
531
FTQPV
536
PKETI
541
PSMED
546
SDVSL
551
TSSPY
556
LTSSI
561
PFGLD
566
SLTSK
571
VKDQL
576
KVSPF
581
LPDAS
586
MEKEL
591
IFDGG
596
LGSGS
601
GQKVD
606
LITWP
611
WSETS
616
SEKSA
621
EPLSK
626
PWLED
631
DDSLL
636
PAEIE
641
DKKLV
646
LVDKM
651
DSTDQ
656
ISKHS
661
KYEHD
666
DRSTH
671
FPEEE
676
PLSGP
681
AVPIF
686
ADTAA
691
ESASL
696
TLPKH
701
ISEVP
706
GVDDY
711
SVTKA
716
PLILT
721
SVAIS
726
ASTDK
731
SDQAD
736
AILRE
741
DMEQI
746
TESSN
751
YEWFD
756
SEVSM
761
VKPDM
766
QTLWT
771
ILPES
776
ERVWT
781
RTSSL
786
EKLSR
791
DILAS
796
TPQSA
801
DRLWL
806
SVTQS
811
TKLPP
816
TTIST
821
LLEDE
826
VIMGV
831
QDISL
836
ELDRI
841
GTDYY
846
QPEQV
851
QEQNG
856
KVGSY
861
VEMST
866
SVHST
871
EMVSV
876
AWPTE
881
GGDDL
886
SYTQT
891
SGALV
896
VFFSL
901
RVTNM
906
MFSED
911
LFNKN
916
SLEYK
921
ALEQR
926
FLELL
931
VPYLQ
936
SNLTG
941
FQNLE
946
ILNFR
951
NGSIV
956
VNSRM
961
KFANS
966
VPPNV
971
NNAVY
976
MILED
981
FCTTA
986
YNTMN
991
LAIDK
996
YSLDV
1001
ESGDE
1006
ANPCK
1011
FQACN
1016
EFSEC
1021
LVNPW
1026
SGEAK
1031
CRCFP
1036
GYLSV
1041
EERPC
1046
QSLCD
1051
LQPDF
1056
CLNDG
1061
KCDIM
1066
PGHGA
1071
ICRCR
1076
VGENW
1081
WYRGK
1086
HCEEF
1091
VSEPV
1096
IIGIT
1101
IASVV
1106
GLLVI
1111
FSAII
1116
YFFIR
1121
TLQAH
1126
HDRSE
1131
RESPF
1136
SGSSR
1141
QPDSL
1146
SSIEN
1151
AVKYN
1156
PVYES
1161
HRAGC
1166
EKYEG
1171
PYPQH
1176
PFYSS
1181
ASGDV
1186
IGGLS
1191
REEIR
1196
QMYES
1201
SELSR
1206
EEIQE
1211
RMRVL
1216
ELYAN
1221
DPEFA
1226
AFVRE
1231
QQVEE
1236
V
1241
Mutation Information
DNA mutation:
c.C149G
Peptide Range:
38 ~ 62
Mut AA position:
50 (13 in Wild Type peptide)
Alignment
Wild Type:
"IQEPKSAVSFLLPEESTDLSLATKK
||||||||||||.||||||||||||
Mutant:
IQEPKSAVSFLLREESTDLSLATKK"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) IMPG2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
IQEPKSAVSFLLREESTDLSLATKK
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT