Immunogenicity 3553

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
SREBF2
Transcript ID
uc003bbi.3
HLA INFO
C*12:03
TCR INFO

No TCR info found!

T cell Tumor cell C*12:03
sequence
Full length protein sequence (1141 aa)
MDDSG
1
ELGGL
6
ETMET
11
LTELG
16
DELTL
21
GDIDE
26
MLQFV
31
SNQVG
36
EFPDL
41
FSEQL
46
CSSFP
51
GSGGS
56
GSSSG
61
SSGSS
66
SSSSN
71
GRGSS
76
SGAVD
81
PSVQR
86
SFTQV
91
TLPSF
96
SPSAA
101
SPQAP
106
TLQVK
111
VSPTS
116
VPTTP
121
RATPI
126
LQPRP
131
QPQPQ
136
PQTQL
141
QQQTV
146
MITPT
151
FSTTP
156
QTRII
161
QQPLI
166
YQNAA
171
TSFQV
176
LQPQV
181
QSLVT
186
SSQVQ
191
PVTIQ
196
QQVQT
201
VQAQR
206
VLTQT
211
ANGTL
216
QTLAP
221
ATVQT
226
VAAPQ
231
VQQVP
236
VLVQP
241
QIIKT
246
DSLVL
251
TTLKT
256
DGSPV
261
MAAVQ
266
NPALT
271
ALTTP
276
IQTAA
281
LQVPT
286
LVGSS
291
GTILT
296
TMPVM
301
MGQEK
306
VPIKQ
311
VPGGV
316
KQLEP
321
PKEGE
326
RRTTH
331
NIIEK
336
RYRSS
341
INDKI
346
IELKD
351
LVMGT
356
DAKMH
361
KSGVL
366
RKAID
371
YIKYL
376
QQVNH
381
KLRQE
386
NMVLK
391
LANQK
396
NKLLK
401
GIDLG
406
SLVDN
411
EVDLK
416
IEDFN
421
QNVLL
426
MSPPA
431
SDSGS
436
QAGFS
441
PYSID
446
SEPGS
451
PLLDD
456
AKVKD
461
EPDSP
466
PVALG
471
MVDRS
476
RILLC
481
VLTFL
486
CLSFN
491
PLTSL
496
LQWGG
501
AHDSD
506
QHPHS
511
GSGRS
516
VLSFE
521
SGSGG
526
WFDWM
531
MPTLL
536
LWLVN
541
GVIVL
546
SVFVK
551
LLVHG
556
EPVIR
561
PHSRS
566
SVTFW
571
RHRKQ
576
ADLDL
581
ARGDF
586
AAAAG
591
NLQTC
596
LAVLG
601
RALPT
606
SRLDL
611
ACSLS
616
WNVIR
621
YSLQK
626
LRLVR
631
WLLKK
636
VFQCR
641
RATPA
646
TEAGF
651
EDEAK
656
TSARD
661
AALAY
666
HRLHQ
671
LHITG
676
KLPAG
681
SACSD
686
VHMAL
691
CAVNL
696
AECAE
701
EKIPP
706
STLVE
711
IHLTA
716
AMGLK
721
TRCGG
726
KLGFL
731
ASYFL
736
SRAQS
741
LCGPE
746
HSAVP
751
DSLRW
756
LCHPL
761
GQKFF
766
MERSW
771
SVKSA
776
AKESL
781
YCAQR
786
NPADP
791
IAQVH
796
QAFCK
801
NLLER
806
AIESL
811
VKPQA
816
KKKAG
821
DQEEE
826
SCEFS
831
SALEY
836
LKLLH
841
SFVDS
846
VGVMS
851
PPLSR
856
SSVLK
861
SALGP
866
DIICR
871
WWTSA
876
ITVAI
881
SWLQG
886
DDAAV
891
RSHFT
896
KVERI
901
PKALE
906
VTESP
911
LVKAI
916
FHACR
921
AMHAS
926
LPGKA
931
DGQQS
936
SFCHC
941
ERASG
946
HLWSS
951
LNVSG
956
ATSDP
961
ALNHV
966
VQLLT
971
CDLLL
976
SLRTA
981
LWQKQ
986
ASASQ
991
AVGET
996
YHASG
1001
AELAG
1006
FQRDL
1011
GSLRR
1016
LAHSF
1021
RPAYR
1026
KVFLH
1031
EATVR
1036
LMAGA
1041
SPTRT
1046
HQLLE
1051
HSLRR
1056
RTTQS
1061
TKHGE
1066
VDAWP
1071
GQRER
1076
ATAIL
1081
LACRH
1086
LPLSF
1091
LSSPG
1096
QRAVL
1101
LAEAA
1106
RTLEK
1111
VGDRR
1116
SCNDC
1121
QQMIV
1126
KLGGG
1131
TAIAA
1136
S
1141
Mutation Information
DNA mutation:
None
Peptide Range:
29 ~ 53
Mut AA position:
41 (13 in Wild Type peptide)
Alignment
Wild Type:
"DEMLQFVSNQVGEFPDLFSEQLCSS
||||||||||||.||||||||||||
Mutant:
DEMLQFVSNQVGQFPDLFSEQLCSS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SREBF2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay