Immunogenicity 3574

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
GRIP2
Transcript ID
uc021wtn.1
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (1140 aa)
MRLSS
1
LTEEA
6
VDGGN
11
GGEWG
16
EDLLE
21
QFTCI
26
PSRVV
31
EAKTA
36
PEWPL
41
CPGEG
46
QGLHG
51
EPLPD
56
HCQGT
61
GGQID
66
PSLGR
71
GGRAK
76
QRGSR
81
GSWWA
86
AGETI
91
ANMLC
96
GLSRE
101
TPGEA
106
DDGPY
111
SKGGK
116
DAGGA
121
DVSLA
126
CRRQS
131
IPEEF
136
RGITV
141
VELIK
146
KEGST
151
LGLTI
156
SGGTD
161
KDGKP
166
RVSNL
171
RPGGL
176
AARSD
181
LLNIG
186
DYIRS
191
VNGIH
196
LTRLR
201
HDEII
206
TLLKN
211
VGERV
216
VLEVE
221
YELPP
226
PAPEN
231
NPRII
236
SKTVD
241
VSLYK
246
EGNSF
251
GFVLR
256
GGAHE
261
DGHKS
266
RPLVL
271
TYVRP
276
GGPAD
281
REGSL
286
KVGDR
291
LLSVD
296
GIPLH
301
GASHA
306
TALAT
311
LRQCS
316
HEALF
321
QVEYD
326
VATPD
331
TVANA
336
SGPLM
341
VEIVK
346
TPGSA
351
LGISL
356
TTTSL
361
RNKSV
366
ITIDR
371
IKPAS
376
VVDRS
381
GALHP
386
GDHIL
391
SIDGT
396
SMEHC
401
SLLEA
406
TKLLA
411
SISEK
416
VRLEI
421
LPVPQ
426
SQRPL
431
RPSEA
436
VKVQR
441
SEQLH
446
RWDPC
451
VPSCH
456
SPRPG
461
HCRMP
466
TWATP
471
AGQDQ
476
SRSLS
481
STPFS
486
SPTLN
491
HAFSC
496
NNPST
501
LPRGS
506
QPMSP
511
RTTMG
516
RRRQR
521
RREHK
526
SSLSL
531
ASSTV
536
GPGGQ
541
IVHTE
546
TTEVV
551
LCGDP
556
LSGFG
561
LQLQG
566
GIFAT
571
ETLSS
576
PPLVC
581
FIEPD
586
SPAER
591
CGLLQ
596
VGDRV
601
LSING
606
IATED
611
GTMEE
616
ANQLL
621
RDAAL
626
AHKVV
631
LEVEF
636
DVAES
641
VIPSS
646
GTFHV
651
KLPKK
656
RSVEL
661
GITIS
666
SASRK
671
RGEPL
676
IISDI
681
KKGSV
686
AHRTG
691
TLEPG
696
DKLLA
701
IDNIR
706
LDNCP
711
MEDAV
716
QILRQ
721
CEDLV
726
KLKIR
731
KDEDN
736
SDELE
741
TTGAV
746
SYTVE
751
LKRYG
756
GPLGI
761
TISGT
766
EEPFD
771
PIVIS
776
GLTKR
781
GLAER
786
TGAIH
791
VGDRI
796
LAINN
801
VSLKG
806
RPLSE
811
AIHLL
816
QVAGE
821
TVTLK
826
IKKQL
831
DRPLL
836
PRKSG
841
SLSET
846
SDADE
851
DPADA
856
LKGGL
861
PAARF
866
SPAVP
871
SVDSA
876
VESWD
881
SSATE
886
GGFGG
891
PGSYT
896
PQAAA
901
RGTTP
906
QERRP
911
GWLRG
916
SPPPT
921
EPRRT
926
SYTPT
931
PADES
936
FPEEE
941
EEDDW
946
EPPTS
951
PAPGP
956
AREEG
961
FWRMF
966
GEALE
971
DLESC
976
GQSEL
981
LRELE
986
ASIMT
991
GTVQR
996
VALEG
1001
RPGHR
1006
PWQRG
1011
REVRA
1016
SPAEM
1021
EELLL
1026
PTPLE
1031
MHKVT
1036
LHKDP
1041
MRHDF
1046
GFSVS
1051
DGLLE
1056
KGVYV
1061
HTVRP
1066
DGPAH
1071
RGGLQ
1076
PFDRV
1081
LQVNH
1086
VRTRD
1091
FDCCL
1096
AVPLL
1101
AEAGD
1106
VLELI
1111
ISRKP
1116
HTAHS
1121
SRAPR
1126
SPGPS
1131
SPRML
1136
Mutation Information
DNA mutation:
None
Peptide Range:
118 ~ 142
Mut AA position:
130 (13 in Wild Type peptide)
Alignment
Wild Type:
"GGKDAGGADVSLACRRQSIPEEFRG
||||||||||||.||||||||||||
Mutant:
GGKDAGGADVSLVCRRQSIPEEFRG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GRIP2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay