Immunogenicity 3585

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
GRM2
Transcript ID
uc010hlv.3
HLA INFO
A*26:01
TCR INFO

No TCR info found!

T cell Tumor cell A*26:01
sequence
Full length protein sequence (872 aa)
MGSLL
1
ALLAL
6
LLLWG
11
AVAEG
16
PAKKV
21
LTLEG
26
DLVLG
31
GLFPV
36
HQKGG
41
PAEDC
46
GPVNE
51
HRGIQ
56
RLEAM
61
LFALD
66
RINRD
71
PHLLP
76
GVRLG
81
AHILD
86
SCSKD
91
THALE
96
QALDF
101
VRASL
106
SRGAD
111
GSRHI
116
CPDGS
121
YATHG
126
DAPTA
131
ITGVI
136
GGSYS
141
DVSIQ
146
VANLL
151
RLFQI
156
PQISY
161
ASTSA
166
KLSDK
171
SRYDY
176
FARTV
181
PPDFF
186
QAKAM
191
AEILR
196
FFNWT
201
YVSTV
206
ASEGD
211
YGETG
216
IEAFE
221
LEARA
226
RNICV
231
ATSEK
236
VGRAM
241
SRAAF
246
EGVVR
251
ALLQK
256
PSARV
261
AVLFT
266
RSEDA
271
RELLA
276
ASQRL
281
NASFT
286
WVASD
291
GWGAL
296
ESVVA
301
GSEGA
306
AEGAI
311
TIELA
316
SYPIS
321
DFASY
326
FQSLD
331
PWNNS
336
RNPWF
341
REFWE
346
QRFRC
351
SFRQR
356
DCAAH
361
SLRAV
366
PFEQE
371
SKIMF
376
VVNAV
381
YAMAH
386
ALHNM
391
HRALC
396
PNTTR
401
LCDAM
406
RPVNG
411
RRLYK
416
DFVLN
421
VKFDA
426
PFRPA
431
DTHNE
436
VRFDR
441
FGDGI
446
GRYNI
451
FTYLR
456
AGSGR
461
YRYQK
466
VGYWA
471
EGLTL
476
DTSLI
481
PWASP
486
SAGPL
491
PASRC
496
SEPCL
501
QNEVK
506
SVQPG
511
EVCCW
516
LCIPC
521
QPYEY
526
RLDEF
531
TCADC
536
GLGYW
541
PNASL
546
TGCFE
551
LPQEY
556
IRWGD
561
AWAVG
566
PVTIA
571
CLGAL
576
ATLFV
581
LGVFV
586
RHNAT
591
PVVKA
596
SGREL
601
CYILL
606
GGVFL
611
CYCMT
616
FIFIA
621
KPSTA
626
VCTLR
631
RLGLG
636
TAFSV
641
CYSAL
646
LTKTN
651
RIARI
656
FGGAR
661
EGAQR
666
PRFIS
671
PASQV
676
AICLA
681
LISGQ
686
LLIVV
691
AWLVV
696
EAPGT
701
GKETA
706
PERRE
711
VVTLR
716
CNHRD
721
ASMLG
726
SLAYN
731
VLLIA
736
LCTLY
741
AFKTR
746
KCPEN
751
FNEAK
756
FIGFT
761
MYTTC
766
IIWLA
771
FLPIF
776
YVTSS
781
DYRVQ
786
TTTMC
791
VSVSL
796
SGSVV
801
LGCLF
806
APKLH
811
IILFQ
816
PQKNV
821
VSHRA
826
PTSRF
831
GSAAA
836
RASSS
841
LGQGS
846
GSQFV
851
PTVCN
856
GREVV
861
DSTTS
866
SL
871
Mutation Information
DNA mutation:
None
Peptide Range:
704 ~ 728
Mut AA position:
716 (13 in Wild Type peptide)
Alignment
Wild Type:
"GTGKETAPERREVVTLRCNHRDASM
||||||||||||.||||||||||||
Mutant:
GTGKETAPERREGVTLRCNHRDASM"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GRM2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay