Immunogenicity 3591

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
ZNF717
Transcript ID
uc011bgi.2
HLA INFO
DQA*01:03 / DQB*03:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*03:02
sequence
Full length protein sequence (914 aa)
MFPVF
1
SGCFQ
6
ELQEK
11
NKSLE
16
LVSFE
21
EVAVH
26
FTWEE
31
WQDLD
36
DAQRT
41
LYRDV
46
MLETY
51
SSLVS
56
LGHYI
61
TKPEM
66
IFKLE
71
QGAEP
76
WIVEE
81
TPNLR
86
LSAVQ
91
IIDDL
96
IERSH
101
ESHDR
106
FFWQI
111
VITNS
116
NTSTQ
121
ERVEL
126
GKTFN
131
LNSNH
136
VLNLI
141
INNGN
146
SSGMK
151
PGQFN
156
DCQNM
161
LFPIK
166
PGETQ
171
SGEKP
176
HVCDI
181
TRRSH
186
RHHEH
191
LTQHH
196
KIQTL
201
LQTFQ
206
CNEQG
211
KTFNT
216
EAMFF
221
IHKRV
226
HIVQT
231
FGKYN
236
EYEKA
241
CNNSA
246
VIVQV
251
ITQVG
256
QPTCC
261
RKSDF
266
TKHQQ
271
THTGE
276
KPYEC
281
VECEK
286
PSISK
291
SDLML
296
QCKMP
301
TEEKP
306
YACNW
311
CEKLF
316
SYKSS
321
LIIHQ
326
RIHTG
331
EKPYG
336
CNECG
341
KTFRR
346
KSFLT
351
LHERT
356
HTGDK
361
PYKCI
366
ECGKT
371
FHCKS
376
LLTLH
381
HRTHS
386
GEKPY
391
QCSEC
396
GKTFS
401
QKSYL
406
TIHHR
411
THTGE
416
KPYAC
421
DHCEE
426
AFSHK
431
SRLTV
436
HQRTH
441
TGEKP
446
YECNE
451
CGKPF
456
INKSN
461
LRLHQ
466
RTHTG
471
EKPYE
476
CNECG
481
KTFHR
486
KSFLT
491
IHQWT
496
HTGEK
501
PYECN
506
ECGKT
511
FRCKS
516
FLTVH
521
QRTHA
526
GEKPY
531
ACNEC
536
GKTYS
541
HKSYL
546
TVHHR
551
THTGE
556
KPYEC
561
NECGK
566
SFHCK
571
SFLTI
576
HQRTH
581
AGKKP
586
YECNE
591
CEKTF
596
INKLN
601
LGIHK
606
RTHTG
611
ERPYE
616
CNECG
621
KTFRQ
626
KSNLS
631
THQGT
636
HTGEK
641
PYVCN
646
ECGKT
651
FHRKS
656
FLTIH
661
QRTHT
666
GKNRM
671
DVMNV
676
EKLFV
681
RNHTL
686
LYIRE
691
LTPGK
696
SPMNV
701
MNVEN
706
PFIRR
711
QIFRS
716
IKVFT
721
RGRNP
726
MNVAN
731
VEKPC
736
QKSVL
741
TVHHR
746
THTGE
751
KPYEC
756
NECGK
761
TFCHK
766
SNLST
771
HQGTH
776
SGEKP
781
YECDE
786
CRKTF
791
YDKTV
796
LTIHQ
801
RTHTG
806
EKPFE
811
CKECR
816
KTFSQ
821
KSKLF
826
VHHRT
831
HTGEK
836
PFRCN
841
ECRKT
846
FSQKS
851
GLSIH
856
QRTHT
861
GEKPY
866
ECKEC
871
GKTFC
876
QKSHL
881
SRHQQ
886
THIGE
891
KSDVA
896
EAGYV
901
FPQNH
906
SFFP
911
Mutation Information
DNA mutation:
None
Peptide Range:
115 ~ 139
Mut AA position:
127 (13 in Wild Type peptide)
Alignment
Wild Type:
"IVITNSNTSTQERVELGKTFNLNSN
||||||||||||.||||||||||||
Mutant:
IVITNSNTSTQETVELGKTFNLNSN"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZNF717

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay