Immunogenicity 361
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
EPHB6
Transcript ID
uc011ksu.2
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (1021 aa)
MATEG
1
AAQLG
6
NRVAG
11
MVCSL
16
WVLLL
21
VSSVL
26
ALEEV
31
LLDTT
36
GETSE
41
IGWLT
46
YPPGG
51
WDEVS
56
VLDDQ
61
RRLTR
66
TFEAC
71
HVAGA
76
PPGTG
81
QDNWL
86
QTHFV
91
ERRGA
96
QRAHI
101
RLHFS
106
VRACS
111
SLGVS
116
GGTCR
121
ETFTL
126
YYRQA
131
EEPDS
136
PDSVS
141
SWHLK
146
RWTKV
151
DTIAA
156
DESFP
161
SSSSS
166
SSSSS
171
SAAWA
176
VGPHG
181
AGQRA
186
GLQLN
191
VKERS
196
FGPLT
201
QRGFY
206
VAFQD
211
TGACL
216
ALVAV
221
RLFSY
226
TCPAV
231
LRSFA
236
SFPET
241
QASGA
246
GGASL
251
VAAVG
256
TCVAH
261
AEPEE
266
DGVGG
271
QAGGS
276
PPRLH
281
CNGEG
286
KWMVA
291
VGGCR
296
CQPGY
301
QPARG
306
DKACQ
311
ACPRG
316
LYKSS
321
AGNAP
326
CSPCP
331
ARSHA
336
PNPAA
341
PVCPC
346
LEGFY
351
RASSD
356
PPEAP
361
CTGPP
366
SAPQE
371
LWFEV
376
QGSAL
381
MLHWR
386
LPREL
391
GGRGD
396
LLFNV
401
VCKEC
406
EGRQE
411
PASGG
416
GGTCH
421
RCRDE
426
VHFDP
431
RQRGL
436
TESRV
441
LVGGL
446
RAHVP
451
YILEV
456
QAVNG
461
VSELS
466
PDPPQ
471
AAAIN
476
VSTSH
481
EVPSA
486
VPVVH
491
QVSRA
496
SNSIT
501
VSWPQ
506
PDQTN
511
GNILD
516
YQLRY
521
YDQAE
526
DESHS
531
FTLTS
536
ETNTA
541
TVTQL
546
SPGHI
551
YGFQV
556
RARTA
561
AGHGP
566
YGGKV
571
YFQTL
576
PQGEL
581
SSQLP
586
ERLSL
591
VIGSI
596
LGALA
601
FLLLA
606
AITVL
611
AVVFQ
616
RKRRG
621
TGYTE
626
QLQQY
631
SSPGL
636
GVKYY
641
IDPST
646
YEDPC
651
QAIRE
656
LAREV
661
DPAYI
666
KIEEV
671
IGTGS
676
FGEVR
681
QGRLQ
686
PRGRR
691
EQTVA
696
IQALW
701
AGGAE
706
SLQMT
711
FLGRA
716
AVLGQ
721
FQHPN
726
ILRLE
731
GVVTK
736
SRPLM
741
VLTEF
746
MELGP
751
LDSFL
756
RQREG
761
QFSSL
766
QLVAM
771
QRGVA
776
AAMQY
781
LSSFA
786
FVHRS
791
LSAHS
796
VLVNS
801
HLVCK
806
VARLG
811
HSPQG
816
PSCLL
821
RWAAP
826
EVIAH
831
GKHTT
836
SSDVW
841
SFGIL
846
MWEVM
851
SYGER
856
PYWDM
861
SEQEV
866
LNAIE
871
QEFRL
876
PPPPG
881
CPPGL
886
HLLML
891
DTWQK
896
DRARR
901
PHFDQ
906
LVAAF
911
DKMIR
916
KPDTL
921
QAGGD
926
PGERP
931
SQALL
936
TPVAL
941
DFPCL
946
DSPQA
951
WLSAI
956
GLECY
961
QDNFS
966
KFGLC
971
TFSDV
976
AQLSL
981
EDLPA
986
LGITL
991
AGHQK
996
KLLHH
1001
IQLLQ
1006
QHLRQ
1011
QGSVE
1016
V
1021
Mutation Information
DNA mutation:
c.G757T
Peptide Range:
241 ~ 265
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"SFPETQASGAGGASLVAAVGTCVAH
||||||||||||.||||||||||||
Mutant:
SFPETQASGAGGSSLVAAVGTCVAH"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) EPHB6
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
SFPETQASGAGGSSLVAAVGTCVAH
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT