Immunogenicity 3632

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
FAM131A
Transcript ID
uc003foe.3
HLA INFO
C*16:01
TCR INFO

No TCR info found!

T cell Tumor cell C*16:01
sequence
Full length protein sequence (366 aa)
MPMIS
1
VLGKM
6
FLWQR
11
EGPGG
16
RWTCQ
21
TSRRV
26
SSDPA
31
WAVEW
36
IELPR
41
GLSLS
46
SLGSA
51
RTLRG
56
WSRSS
61
RPSSV
66
DSQDL
71
PEVNV
76
GDTVA
81
MLPKS
86
RRALT
91
IQEIA
96
ALARS
101
SLHGI
106
SQVVK
111
DHVTK
116
PTAMA
121
QGRVA
126
HLIEW
131
KGWSK
136
PSDSP
141
AALES
146
AFSSY
151
SDLSE
156
GEQEA
161
RFAAG
166
VAEQF
171
AIAEA
176
KLRAW
181
SSVDG
186
EDSTD
191
DSYDE
196
DFAGG
201
MDTDM
206
AGQLP
211
LGPHL
216
QDLFT
221
GHRFS
226
RPVRQ
231
GSVEP
236
ESDCS
241
QTVSP
246
DTLCS
251
SLCSL
256
EDGLL
261
GSPAR
266
LASQL
271
LGDEL
276
LLAKL
281
PPSRE
286
SAFRS
291
LGPLE
296
AQDSL
301
YNSPL
306
TESCL
311
SPAEE
316
EPAPC
321
KDCQP
326
LCPPL
331
TGSWE
336
RQRQA
341
SDLAS
346
SGVVS
351
LDEDE
356
AEPEE
361
Q
366
Mutation Information
DNA mutation:
None
Peptide Range:
43 ~ 67
Mut AA position:
55 (13 in Wild Type peptide)
Alignment
Wild Type:
"LPRGLSLSSLGSARTLRGWSRSSRP
||||||||||||.||||||||||||
Mutant:
LPRGLSLSSLGSVRTLRGWSRSSRP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) FAM131A

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay