Immunogenicity 365
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
MSLN
Transcript ID
uc010brd.1
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (622 aa)
MALPT
1
ARPLL
6
GSCGT
11
PALGS
16
LLFLL
21
FSLGW
26
VQPSR
31
TLAGE
36
TGQEA
41
APLDG
46
VLANP
51
PNISS
56
LSPRQ
61
LLGFP
66
CAEVS
71
GLSTE
76
RVREL
81
AVALA
86
QKNVK
91
LSTEQ
96
LRCLA
101
HRLSE
106
PPEDL
111
DALPL
116
DLLLF
121
LNPDA
126
FSGPQ
131
ACTRF
136
FSRIT
141
KANVD
146
LLPRG
151
APERQ
156
RLLPA
161
ALACW
166
GVRGS
171
LLSEA
176
DVRAL
181
GGLAC
186
DLPGR
191
FVAES
196
AEVLL
201
PRLVS
206
CPGPL
211
DQDQQ
216
EAARA
221
ALQGG
226
GPPYG
231
PPSTW
236
SVSTM
241
DALRG
246
LLPVL
251
GQPII
256
RSIPQ
261
GIVAA
266
WRQRS
271
SRDPS
276
WRQPE
281
RTILR
286
PRFRR
291
EVEKT
296
ACPSG
301
KKARE
306
IDESL
311
IFYKK
316
WELEA
321
CVDAA
326
LLATQ
331
MDRVN
336
AIPFT
341
YEQLD
346
VLKHK
351
LDELY
356
PQGYP
361
ESVIQ
366
HLGYL
371
FLKMS
376
PEDIR
381
KWNVT
386
SLETL
391
KALLE
396
VNKGH
401
EMSPQ
406
VATLI
411
DRFVK
416
GRGQL
421
DKDTL
426
DTLTA
431
FYPGY
436
LCSLS
441
PEELS
446
SVPPS
451
SIWAV
456
RPQDL
461
DTCDP
466
RQLDV
471
LYPKA
476
RLAFQ
481
NMNGS
486
EYFVK
491
IQSFL
496
GGAPT
501
EDLKA
506
LSQQN
511
VSMDL
516
ATFMK
521
LRTDA
526
VLPLT
531
VAEVQ
536
KLLGP
541
HVEGL
546
KAEER
551
HRPVR
556
DWILR
561
QRQDD
566
LDTLG
571
LGLQG
576
GIPNG
581
YLVLD
586
LSMQE
591
ALSGT
596
PCLLG
601
PGPVL
606
TVLAL
611
LLAST
616
LA
621
Mutation Information
DNA mutation:
c.T374A
Peptide Range:
114 ~ 138
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"DLDALPLDLLLFLNPDAFSGPQACT
||||||||||||.||||||||||||
Mutant:
DLDALPLDLLLFHNPDAFSGPQACT"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) MSLN
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
DLDALPLDLLLFHNPDAFSGPQACT
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT