Immunogenicity 3686
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
LIMCH1
Transcript ID
uc003gvz.4
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1467 aa)
MRKDT
1
DDIES
6
PKRSI
11
RDSGY
16
IDCWD
21
SERSD
26
SLSPP
31
RHGRD
36
DSFDS
41
LDSFG
46
SRSRQ
51
TPSPD
56
VVLRG
61
SSDGR
66
GSDSE
71
SDLPH
76
RKLPD
81
VKKDD
86
MSARR
91
TSHGE
96
PKSAV
101
PFNQY
106
LPNKS
111
NQTAY
116
VPAPL
121
RKKKA
126
EREEY
131
RKSWS
136
TATSP
141
LGGER
146
PFSFP
151
ETIEE
156
EGSEV
161
GSAGE
166
DNPAG
171
QMNPG
176
WKPSD
181
GGCEL
186
PDGSG
191
KEHPS
196
SDGAV
201
VAPAP
206
KSEEK
211
DAAEI
216
QKRKR
221
LEQAG
226
IKVMP
231
AAQRF
236
ASQKQ
241
LSEEK
246
EAIRD
251
IVLRK
256
ENSFL
261
THQHG
266
NDSEA
271
EGEVV
276
CRLPD
281
LEKDD
286
FAARR
291
ARMNQ
296
TKPMV
301
PLNQL
306
LYGPY
311
PKKGA
316
EKSDG
321
SKQLS
326
KGISK
331
KRSLE
336
YKRNQ
341
GHTEE
346
VKLIV
351
TCNMR
356
AQESE
361
PVEGG
366
LRKVP
371
DLHKD
376
DLAQQ
381
RIQGS
386
LAPHR
391
EPPSF
396
ITLSN
401
ITEAD
406
LETWE
411
RLKVS
416
EKARD
421
GDVQH
426
ICASE
431
PSPEI
436
KAETA
441
IRDDF
446
ANRKA
451
RASKK
456
ASSPR
461
QKFVH
466
FGPVT
471
ELDQQ
476
KWKRL
481
SIGKA
486
GPRED
491
EEEVI
496
CHGSK
501
IQMDS
506
VSPVS
511
AATSS
516
LKGHQ
521
IFNRQ
526
NDCRT
531
MNCGR
536
GDYCR
541
RASWL
546
APVPE
551
SQEEW
556
VCSLG
561
ECPRG
566
TEEVT
571
SKQLP
576
QDGKE
581
ETESA
586
PRDSE
591
RLSKA
596
ERSED
601
SSQPL
606
VCPLA
611
SECEA
616
SGTEE
621
KLEKM
626
TAPAW
631
SGSGL
636
KGQRK
641
LDDSR
646
KDDMM
651
ARRTG
656
MSLRH
661
TGSNP
666
NQFLP
671
VPFAK
676
QQDVE
681
ESSKG
686
LPMKD
691
QRYGP
696
RTPVS
701
DDAES
706
TSMFD
711
MRCEE
716
EAAVQ
721
PHSRA
726
RQEQL
731
QLINN
736
QLREE
741
DDKWQ
746
DDLAR
751
WKSRR
756
RSVSQ
761
DLIKK
766
EEERK
771
KMEKL
776
LAGED
781
GTSER
786
RKSIK
791
TYREI
796
VQEKE
801
RRERE
806
LHEAY
811
KNARS
816
QEEAE
821
GILQQ
826
YIERF
831
TISEA
836
VLERL
841
EMPKI
846
LERSH
851
STEPN
856
LSSFL
861
NDPNP
866
MKYLR
871
QQSLP
876
PPKFT
881
ATVET
886
TIARA
891
SVLDT
896
SMSAG
901
SGSPS
906
KTVTP
911
KAVPM
916
LTPKP
921
YSQPK
926
NSQDV
931
LKTFK
936
VDGKV
941
SVNGE
946
TVHRE
951
EEKER
956
ECPTV
961
APAHS
966
LTKSQ
971
MFEGV
976
ARVHG
981
SPLEL
986
KQDNG
991
SIEIN
996
IKKPN
1001
SVPQE
1006
LAATT
1011
EKTEP
1016
NSQED
1021
KNDGG
1026
KSRKG
1031
NIELA
1036
SSEPQ
1041
HFTTT
1046
VTRCS
1051
PTVAF
1056
VEFPS
1061
SPQLK
1066
NDVSE
1071
EKDQK
1076
KPENE
1081
MSGKV
1086
ELVLS
1091
QKVVK
1096
PKSPE
1101
PEATL
1106
TFPFL
1111
DKMPE
1116
ANQLH
1121
LPNLN
1126
SQVDS
1131
PSSEK
1136
SPVMT
1141
PFKFW
1146
AWDPE
1151
EERRR
1156
QEKWQ
1161
QEQER
1166
LLQER
1171
YQKEQ
1176
DKLKE
1181
EWEKA
1186
QKEVE
1191
EEERR
1196
YYEEE
1201
RKIIE
1206
DTVVP
1211
FTVSS
1216
SSADQ
1221
LSTSS
1226
SMTEG
1231
SGTMN
1236
KIDLG
1241
NCQDE
1246
KQDRR
1251
WKKSF
1256
QGDDS
1261
DLLLK
1266
TRESD
1271
RLEEK
1276
GSLTE
1281
GALAH
1286
SGNPV
1291
SKGVH
1296
EDHQL
1301
DTEAG
1306
APHCG
1311
TNPQL
1316
AQDPS
1321
QNQQT
1326
SNPTH
1331
SSEDV
1336
KPKTL
1341
PLDKS
1346
INHQI
1351
ESPSE
1356
RRKKS
1361
PREHF
1366
QAGPF
1371
SPCSP
1376
TPPGQ
1381
SPNRS
1386
ISGKK
1391
LCSSC
1396
GLPLG
1401
KGAAM
1406
IIETL
1411
NLYFH
1416
IQCFR
1421
CGICK
1426
GQLGD
1431
AVSGT
1436
DVRIR
1441
NGLLN
1446
CNDCY
1451
MRSRS
1456
AGQPT
1461
TL
1466
Mutation Information
DNA mutation:
None
Peptide Range:
542 ~ 566
Mut AA position:
554 (13 in Wild Type peptide)
Alignment
Wild Type:
"DYCRRASWLAPVPESQEEWVCSLGE
||||||||||||.||||||||||||
Mutant:
DYCRRASWLAPVLESQEEWVCSLGE"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) LIMCH1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay