Immunogenicity 37

summary
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
TLN2
Transcript ID
uc002alb.4
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (2557 aa)
MVALS
1
LKICV
6
RHCNV
11
VKTMQ
16
FEPST
21
AVYDA
26
CRVIR
31
ERVPE
36
AQTGQ
41
ASDYG
46
LFLSD
51
EDPRK
56
GIWLE
61
AGRTL
66
DYYML
71
RNGDI
76
LEYKK
81
KQRPQ
86
KIRML
91
DGSVK
96
TVMVD
101
DSKTV
106
GELLV
111
TICSR
116
IGITN
121
YEEYS
126
LIQET
131
IEEKK
136
EEGTG
141
TLKKD
146
RTLLR
151
DERKM
156
EKLKA
161
KLHTD
166
DDLNW
171
LDHSR
176
TFREQ
181
GVDEN
186
ETLLL
191
RRKFF
196
YSDQN
201
VDSRD
206
PVQLN
211
LLYVQ
216
ARDDI
221
LNGSH
226
PVSFE
231
KACEF
236
GGFQA
241
QIQFG
246
PHVEH
251
KHKPG
256
FLDLK
261
EFLPK
266
EYIKQ
271
RGAEK
276
RIFQE
281
HKNCG
286
EMSEI
291
EAKVK
296
YVKLA
301
RSLRT
306
YGVSF
311
FLVKE
316
KMKGK
321
NKLVP
326
RLLGI
331
TKDSV
336
MRVDE
341
KTKEV
346
LQEWP
351
LTTVK
356
RWAAS
361
PKSFT
366
LDFGE
371
YQESY
376
YSVQT
381
TEGEQ
386
ISQLI
391
AGYID
396
IILKK
401
KQSKD
406
RFGLE
411
GDEES
416
TMLEE
421
SVSPK
426
KSTIL
431
QQQFN
436
RTGKA
441
EHGSV
446
ALPAV
451
MRSGS
456
SGPET
461
FNVGS
466
MPSPQ
471
QQVMV
476
GQMHR
481
GHMPP
486
LTSAQ
491
QALMG
496
TINTS
501
MHAVQ
506
QAQDD
511
LSELD
516
SLPPL
521
GQDMA
526
SRVWV
531
QNKVD
536
ESKHE
541
IHSQV
546
DAITA
551
GTASV
556
VNLTA
561
GDPAD
566
TDYTA
571
VGCAI
576
TTISS
581
NLTEM
586
SKGVK
591
LLAAL
596
MDDEV
601
GSGED
606
LLRAA
611
RTLAG
616
AVSDL
621
LKAVQ
626
PTSGE
631
PRQTV
636
LTAAG
641
SIGQA
646
SGDLL
651
RQIGE
656
NETDE
661
RFQDV
666
LMSLA
671
KAVAN
676
AAAML
681
VLKAK
686
NVAQV
691
AEDTV
696
LQNRV
701
IAAAT
706
QCALS
711
TSQLV
716
ACAKV
721
VSPTI
726
SSPVC
731
QEQLI
736
EAGKL
741
VDRSV
746
ENCVR
751
ACQAA
756
TTDSE
761
LLKQV
766
SAAAS
771
VVSQA
776
LHDLL
781
QHVRQ
786
FASRG
791
EPIGR
796
YDQAT
801
DTIMC
806
VTESI
811
FSSMG
816
DAGEM
821
VRQAR
826
VLAQA
831
TSDLV
836
NAMRS
841
DAEAE
846
IDMEN
851
SKKLL
856
AAAKL
861
LADST
866
ARMVE
871
AAKGA
876
AANPE
881
NEDQQ
886
QRLRE
891
AAEGL
896
RVATN
901
AAAQN
906
AIKKK
911
IVNRL
916
EVAAK
921
QAAAA
926
ATQTI
931
AASQN
936
AAVSN
941
KNPAA
946
QQQLV
951
QSCKA
956
VADHI
961
PQLVQ
966
GVRGS
971
QAQAE
976
DLSAQ
981
LALII
986
SSQNF
991
LQPGS
996
KMVSS
1001
AKAAV
1006
PTVSD
1011
QAAAM
1016
QLSQC
1021
AKNLA
1026
TSLAE
1031
LRTAS
1036
QKAHE
1041
ACGPM
1046
EIDSA
1051
LNTVQ
1056
TLKNE
1061
LQDAK
1066
MAAVE
1071
SQLKP
1076
LPGET
1081
LEKCA
1086
QDLGS
1091
TSKAV
1096
GSSMA
1101
QLLTC
1106
AAQGN
1111
EHYTG
1116
VAARE
1121
TAQAL
1126
KTLAQ
1131
AARGV
1136
AASTT
1141
DPAAA
1146
HAMLD
1151
SARDV
1156
MEGSA
1161
MLIQE
1166
AKQAL
1171
IAPGD
1176
AERQQ
1181
RLAQV
1186
AKAVS
1191
HSLNN
1196
CVNCL
1201
PGQKD
1206
VDVAL
1211
KSIGE
1216
SSKKL
1221
LVDSL
1226
PPSTK
1231
PFQEA
1236
QSELN
1241
QAAAD
1246
LNQSA
1251
GEVVH
1256
ATRGQ
1261
SGELA
1266
AASGK
1271
FSDDF
1276
DEFLD
1281
AGIEM
1286
AGQAQ
1291
TKEDQ
1296
IQVIG
1301
NLKNI
1306
SMASS
1311
KLLLA
1316
AKSLS
1321
VDPGA
1326
PNAKN
1331
LLAAA
1336
ARAVT
1341
ESINQ
1346
LITLC
1351
TQQAP
1356
GQKEC
1361
DNALR
1366
ELETV
1371
KGMLD
1376
NPNEP
1381
VSDLS
1386
YFDCI
1391
ESVME
1396
NSKVL
1401
GESMA
1406
GISQN
1411
AKTGD
1416
LPAFG
1421
ECVGI
1426
ASKAL
1431
CGLTE
1436
AAAQA
1441
AYLVG
1446
ISDPN
1451
SQAGH
1456
QGLVD
1461
PIQFA
1466
RANQA
1471
IQMAC
1476
QNLVD
1481
PGSSP
1486
SQVLS
1491
AATIV
1496
AKHTS
1501
ALCNA
1506
CRIAS
1511
SKTAN
1516
PVAKR
1521
HFVQS
1526
AKEVA
1531
NSTAN
1536
LVKTI
1541
KALDG
1546
DFSED
1551
NRNKC
1556
RIATA
1561
PLIEA
1566
VENLT
1571
AFASN
1576
PEFVS
1581
IPAQI
1586
SSEGS
1591
QAQEP
1596
ILVSA
1601
KTMLE
1606
SSSYL
1611
IRTAR
1616
SLAIN
1621
PKDPP
1626
TWSVL
1631
AGHSH
1636
TVSDS
1641
IKSLI
1646
TSIRD
1651
KAPGQ
1656
RECDY
1661
SIDGI
1666
NRCIR
1671
DIEQA
1676
SLAAV
1681
SQSLA
1686
TRDDI
1691
SVEAL
1696
QEQLT
1701
SVVQE
1706
IGHLI
1711
DPIAT
1716
AARGE
1721
AAQLG
1726
HKVTQ
1731
LASYF
1736
EPLIL
1741
AAVGV
1746
ASKIL
1751
DHQQQ
1756
MTVLD
1761
QTKTL
1766
AESAL
1771
QMLYA
1776
AKEGG
1781
GNPKA
1786
QHTHD
1791
AITEA
1796
AQLMK
1801
EAVDD
1806
IMVTL
1811
NEAAS
1816
EVGLV
1821
GGMVD
1826
AIAEA
1831
MSKLD
1836
EGTPP
1841
EPKGT
1846
FVDYQ
1851
TTVVK
1856
YSKAI
1861
AVTAQ
1866
EMMTK
1871
SVTNP
1876
EELGG
1881
LASQM
1886
TSDYG
1891
HLAFQ
1896
GQMAA
1901
ATAEP
1906
EEIGF
1911
QIRTR
1916
VQDLG
1921
HGCIF
1926
LVQKA
1931
GALQV
1936
CPTDS
1941
YTKRE
1946
LIECA
1951
RAVTE
1956
KVSLV
1961
LSALQ
1966
AGNKG
1971
TQACI
1976
TAATA
1981
VSGII
1986
ADLDT
1991
TIMFA
1996
TAGTL
2001
NAENS
2006
ETFAD
2011
HRENI
2016
LKTAK
2021
ALVED
2026
TKLLV
2031
SGAAS
2036
TPDKL
2041
AQAAQ
2046
SSAAT
2051
ITQLA
2056
EVVKL
2061
GAASL
2066
GSDDP
2071
ETQVV
2076
LINAI
2081
KDVAK
2086
ALSDL
2091
ISATK
2096
GAASK
2101
PVDDP
2106
SMYQL
2111
KGAAK
2116
VMVTN
2121
VTSLL
2126
KTVKA
2131
VEDEA
2136
TRGTR
2141
ALEAT
2146
IECIK
2151
QELTV
2156
FQSKD
2161
VPEKT
2166
SSPEE
2171
SIRMT
2176
KGITM
2181
ATAKA
2186
VAAGN
2191
SCRQE
2196
DVIAT
2201
ANLSR
2206
KAVSD
2211
MLTAC
2216
KQASF
2221
HPDVS
2226
DEVRT
2231
RALRF
2236
GTECT
2241
LGYLD
2246
LLEHV
2251
LVILQ
2256
KPTPE
2261
FKQQL
2266
AAFSK
2271
RVAGA
2276
VTELI
2281
QAAEA
2286
MKGTE
2291
WVDPE
2296
DPTVI
2301
AETEL
2306
LGAAA
2311
SIEAA
2316
AKKLE
2321
QLKPR
2326
AKPKQ
2331
ADETL
2336
DFEEQ
2341
ILEAA
2346
KSIAA
2351
ATSAL
2356
VKSAS
2361
AAQRE
2366
LVAQG
2371
KVGSI
2376
PANAA
2381
DDGQW
2386
SQGLI
2391
SAARM
2396
VAAAT
2401
SSLCE
2406
AANAS
2411
VQGHA
2416
SEEKL
2421
ISSAK
2426
QVAAS
2431
TAQLL
2436
VACKV
2441
KADQD
2446
SEAMR
2451
RLQVM
2456
VTDAG
2461
GKILL
2466
LERAA
2471
GNAVK
2476
RASDN
2481
LVRAA
2486
QKAAF
2491
GKADD
2496
DDVVV
2501
KTKFV
2506
GGIAQ
2511
IIAAQ
2516
EEMLK
2521
KEREL
2526
EEARK
2531
KLAQI
2536
RQQQY
2541
KFLPT
2546
ELRED
2551
EG
2556
Mutation Information
DNA mutation:
c.A716G
Peptide Range:
227 ~ 251
Mut AA position:
239 (13 in Wild Type peptide)
Alignment
Wild Type:
"NGSHPVSFEKACEFGGFQAQIQFGP
||||||||||||.||||||||||||
Mutant:
NGSHPVSFEKACGFGGFQAQIQFGP"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

NGSHPVSFEKACGFGGFQAQIQFGP

Antigen Type

TMG

T-cell Source

TILs

APC Type

DSs

Assay

ELISPOT