Immunogenicity 3710

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
MGAT4D
Transcript ID
uc031shc.1
HLA INFO
DQA*03:01 / DQB*06:01
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*03:01 DQB*06:01
sequence
Full length protein sequence (374 aa)
MRTKQ
1
VNLLI
6
TLVAV
11
ALFSF
16
SCFSI
21
YRITQ
26
TNNQL
31
INCRN
36
HILEF
41
KENML
46
HLRNK
51
TEKNT
56
QEMMK
61
VLNRM
66
KYEIT
71
KREIL
76
SGNLV
81
AQKAD
86
ILNKN
91
ETVSN
96
TFEDL
101
KFFFP
106
HLRKE
111
GRIYP
116
DVIIG
121
KGKTG
126
VSFAL
131
GISTV
136
NRGNY
141
SYLKQ
146
TLTSV
151
VSRMT
156
LSQEK
161
DSVVI
166
VLVAD
171
SNEDY
176
LHSVV
181
KMITK
186
KFKRQ
191
VRSGS
196
LEVIS
201
IPAFL
206
YSSML
211
NAKHL
216
AEASQ
221
KLASW
226
RIKQV
231
LDFCI
236
LLLYA
241
QPKAK
246
YYLQL
251
EDDII
256
AKEMY
261
FTKIT
266
DFVGN
271
ISSNN
276
WFFIE
281
FSMLG
286
FIGKL
291
FRSED
296
LTHFV
301
RFFLM
306
FYKEK
311
PIDWL
316
LNDIF
321
QVKVC
326
DAGED
331
LRNCM
336
KRKKQ
341
IRIQY
346
KPSLF
351
QHVGI
356
HSSFP
361
RKEQY
366
EKKI
371
Mutation Information
DNA mutation:
None
Peptide Range:
230 ~ 254
Mut AA position:
242 (13 in Wild Type peptide)
Alignment
Wild Type:
"WRIKQVLDFCILLLYAQPKAKYYLQ
||||||||||||.||||||||||||
Mutant:
WRIKQVLDFCILMLYAQPKAKYYLQ"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) LOC152586

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay