Immunogenicity 3720

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
HHIP
Transcript ID
uc003ijs.2
HLA INFO
DQA*03:01 / DQB*06:01
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*03:01 DQB*06:01
sequence
Full length protein sequence (700 aa)
MLKML
1
SFKLL
6
LLAVA
11
LGFFE
16
GDAKF
21
GERNE
26
GSGAR
31
RRRCL
36
NGNPP
41
KRLKR
46
RDRRM
51
MSQLE
56
LLSGG
61
EMLCG
66
GFYPR
71
LSCCL
76
RSDSP
81
GLGRL
86
ENKIF
91
SVTNN
96
TECGK
101
LLEEI
106
KCALC
111
SPHSQ
116
SLFHS
121
PEREV
126
LERDL
131
VLPLL
136
CKDYC
141
KEFFY
146
TCRGH
151
IPGFL
156
QTTAD
161
EFCFY
166
YARKD
171
GGLCF
176
PDFPR
181
KQVRG
186
PASNY
191
LDQME
196
EYDKV
201
EEISR
206
KHKHN
211
CFCIQ
216
EVVSG
221
LRQPV
226
GALHS
231
GDGSQ
236
RLFIL
241
EKEGY
246
VKILT
251
PEGEI
256
FKEPY
261
LDIHK
266
LVQSG
271
IKGGD
276
ERGLL
281
SLAFH
286
PNYKK
291
NGKLY
296
VSYTT
301
NQERW
306
AIGPH
311
DHILR
316
VVEYT
321
VSRKN
326
PHQVD
331
LRTAR
336
VFLEV
341
AELHR
346
KHLGG
351
QLLFG
356
PDGFL
361
YIILG
366
DGMIT
371
LDDME
376
EMDGL
381
SDFTG
386
SVLRL
391
DVDTD
396
MCNVP
401
YSIPR
406
SNPHF
411
NSTNQ
416
PPEVF
421
AHGLH
426
DPGRC
431
AVDRH
436
PTDIN
441
INLTI
446
LCSDS
451
NGKNR
456
SSARI
461
LQIIK
466
GKDYE
471
SEPSL
476
LEFKP
481
FSNGP
486
LVGGF
491
VYRGC
496
QSERL
501
YGSYV
506
FGDRN
511
GNFLT
516
LQQSP
521
VTKQW
526
QEKPL
531
CLGTS
536
GSCRG
541
YFSGH
546
ILGFG
551
EDELG
556
EVYIL
561
SSSKS
566
MTQTH
571
NGKLY
576
KIVDP
581
KRPLM
586
PEECR
591
ATVQP
596
AQTLT
601
SECSR
606
LCRNG
611
YCTPT
616
GKCCC
621
SPGWE
626
GDFCR
631
TAKCE
636
PACRH
641
GGVCV
646
RPNKC
651
LCKKG
656
YLGPQ
661
CEQVD
666
RNIRR
671
VTRAG
676
ILDQI
681
IDMTS
686
YLLDL
691
TSYIV
696
Mutation Information
DNA mutation:
None
Peptide Range:
322 ~ 346
Mut AA position:
334 (13 in Wild Type peptide)
Alignment
Wild Type:
"VEYTVSRKNPHQVDLRTARVFLEVA
||||||||||||.||||||||||||
Mutant:
VEYTVSRKNPHQIDLRTARVFLEVA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) HHIP

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay