Immunogenicity 374
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
EYS
Transcript ID
uc011dxu.1
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (3144 aa)
MTDKS
1
IVILS
6
LMVFH
11
SSFIN
16
GKTCR
21
RQLVE
26
EWHPQ
31
PSSYV
36
VNWTL
41
TENIC
46
LDFYR
51
DCWFL
56
GVNTK
61
IDTSG
66
NQAVP
71
QICPL
76
QIQLG
81
DILVI
86
SSEPS
91
LQFPE
96
INLMN
101
VSETS
106
FVGCV
111
QNTTT
116
EDQLL
121
FGCRL
126
KGMHT
131
VNSKW
136
LSVGT
141
HYFIT
146
VMASG
151
PSPCP
156
LGLRL
161
NVTVK
166
QQFCQ
171
ESLSS
176
EFCSG
181
HGKCL
186
SEAWS
191
KTYSC
196
HCQPP
201
FSGKY
206
CQELD
211
ACSFK
216
PCKNN
221
GSCIN
226
KRENW
231
DEQAY
236
ECVCH
241
PPFTG
246
KNCSE
251
IIGQC
256
QPHVC
261
FHGNC
266
SNITS
271
NSFIC
276
ECDEQ
281
FSGPF
286
CEVSA
291
KPCVS
296
LLFWK
301
RGICP
306
NSSSA
311
YTYEC
316
PKGSS
321
SQNGE
326
TDVSE
331
FSLVP
336
CQNGT
341
DCIKI
346
SNDVM
351
CICSP
356
IFTDL
361
LCKSI
366
QTSCE
371
SFPLR
376
NNATC
381
KKCEK
386
DYPCS
391
CISGF
396
TEKNC
401
EKAID
406
HCKLL
411
SINCL
416
NEEWC
421
FNIIG
426
RFKYV
431
CIPGC
436
TKNPC
441
WFLKN
446
VYLIH
451
QHLCY
456
CGVTF
461
HGICQ
466
DKGPA
471
QFEYV
476
WQLGF
481
AGSEG
486
EKCQG
491
VIDAY
496
FFLAA
501
NCTED
506
ATYVN
511
DPEDN
516
NSSCW
521
FPHEG
526
TKEIC
531
ANGCS
536
CLSEE
541
DSQEY
546
RYLCF
551
LRWAG
556
NMYLE
561
NTTDD
566
QENEC
571
QHEAV
576
CKDEI
581
NRPRC
586
SCSLS
591
YIGRL
596
CVVNV
601
DYCLG
606
NHSIS
611
VHGLC
616
LALSH
621
NCNCS
626
GLQRY
631
ERNIC
636
EIDTE
641
DCKSA
646
SCKNG
651
TTSTH
656
LRGYF
661
FRKCV
666
PGFKG
671
TQCEI
676
DIDEC
681
ASHPC
686
KNGAT
691
CIDQP
696
GNYFC
701
QCVPP
706
FKVVD
711
GFSCL
716
CNPGY
721
VGIRC
726
EQDID
731
DCILN
736
ACEHN
741
STCKD
746
LHLSY
751
QCVCL
756
SDWEG
761
NFCEQ
766
ESNEC
771
KMNPC
776
KNNST
781
CTDLY
786
KSYRC
791
ECTSG
796
WTGQN
801
CSEEI
806
NECDS
811
DPCMN
816
GGLCH
821
ESTIP
826
GQFVC
831
LCPPL
836
YTGQF
841
CHQRY
846
NLCDL
851
LHNPC
856
RNNST
861
CLALV
866
DANQH
871
CICRE
876
EFEGK
881
NCEID
886
VKDCL
891
FLSCQ
896
DYGDC
901
EDMVN
906
NFRCI
911
CRPGF
916
SGSLC
921
EIEIN
926
ECSSE
931
PCKNN
936
GTCVD
941
LTNRF
946
FCNCE
951
PEYHG
956
PFCEL
961
DVNKC
966
KISPC
971
LDEEN
976
CVYRT
981
DGYNC
986
LCAPG
991
YTGIN
996
CEINL
1001
DECLS
1006
EPCLH
1011
DGVCI
1016
DGINH
1021
YTCDC
1026
KSGFF
1031
GTHCE
1036
TNAND
1041
CLSNP
1046
CLHGR
1051
CTELI
1056
NEYPC
1061
SCDAD
1066
GTSTQ
1071
CKIKI
1076
NDCTS
1081
IPCMN
1086
EGFCQ
1091
KSAHG
1096
FTCIC
1101
PRGYT
1106
GAYCE
1111
KSIDN
1116
CAEPE
1121
LNSVI
1126
CLNGG
1131
ICVDG
1136
PGHTF
1141
DCRCL
1146
PGFSG
1151
QFCEI
1156
NINEC
1161
SSSPC
1166
LHGAD
1171
CEDHI
1176
NGYVC
1181
KCQPG
1186
WSGHH
1191
CENEL
1196
ECIPN
1201
SCVHE
1206
LCMEN
1211
EPGST
1216
CLCTP
1221
GFMTC
1226
SIGLL
1231
CGDEI
1236
RRITC
1241
LTPIF
1246
QRTDP
1251
ISTQT
1256
YTIPP
1261
SETLV
1266
SSFPS
1271
IKATR
1276
IPAIM
1281
DTYPV
1286
DQGPK
1291
QTGIV
1296
KHDIL
1301
PTTGL
1306
ATLRI
1311
STPLE
1316
SYLLQ
1321
ELIVT
1326
RELSA
1331
KHSLL
1336
SSADV
1341
SSSRF
1346
LNFGI
1351
RDPAQ
1356
IVQDK
1361
TSVSH
1366
MPIRT
1371
SAATL
1376
GFFFP
1381
DRRAR
1386
TPFIM
1391
SSLMS
1396
DFIFP
1401
TQSLL
1406
FENCQ
1411
TVALS
1416
ATPTT
1421
SVIRS
1426
IPGAD
1431
IELNR
1436
QSLLS
1441
RGFLL
1446
IAASI
1451
SATPV
1456
VSRGA
1461
QEDIE
1466
EYSAD
1471
SLISR
1476
REHWR
1481
LLSPS
1486
MSPIF
1491
PAKVI
1496
ISKQV
1501
TILNS
1506
SALHR
1511
FSTKA
1516
FNPSE
1521
YQAIT
1526
EASSN
1531
QRLTN
1536
IKSQA
1541
ADSLR
1546
ELSQT
1551
CATCS
1556
MTEIK
1561
SSREF
1566
SDQVL
1571
HSKQS
1576
HFYET
1581
FWMNS
1586
AILAS
1591
WYALM
1596
GAQTI
1601
TSGHS
1606
FSSAT
1611
EITPS
1616
VAFTE
1621
VPSLF
1626
PSKKS
1631
AKRTI
1636
LSSSL
1641
EESIT
1646
LSSNL
1651
DVNLC
1656
LDKTC
1661
LSIVP
1666
SQTIS
1671
SDLMN
1676
SDLTS
1681
KMTTD
1686
ELSVS
1691
ENILK
1696
LLKIR
1701
QYGIT
1706
MGPTE
1711
VLNQE
1716
SLLDM
1721
EKSKG
1726
SHTLF
1731
KLHPS
1736
DSSLD
1741
FELNL
1746
QIYPD
1751
VTLKT
1756
YSEIT
1761
HANDF
1766
KNNLP
1771
PLTGS
1776
VPDFS
1781
EVTTN
1786
VAFYT
1791
VSATP
1796
ALSIQ
1801
TSSSM
1806
SVIRP
1811
DWPYF
1816
TDYMT
1821
SLKKE
1826
VKTSS
1831
EWSKW
1836
ELQPS
1841
VQYQE
1846
FPTAS
1851
RHLPF
1856
TRSLT
1861
LSSLE
1866
SILAP
1871
QRLMI
1876
SDFSC
1881
VRYYG
1886
DSYLE
1891
FQNVA
1896
LNPQN
1901
NISLE
1906
FQTFS
1911
SYGLL
1916
LYVKQ
1921
DSNLV
1926
DGFFI
1931
QLFIE
1936
NGTLK
1941
YHFYC
1946
PGEAK
1951
FKSIN
1956
TTVRV
1961
DNGQK
1966
YTLLI
1971
RQELD
1976
PCNAE
1981
LTILG
1986
RNTQI
1991
CESIN
1996
HVLGK
2001
PLPKS
2006
GSVFI
2011
GGFPD
2016
LHGKI
2021
QMPVP
2026
VKNFT
2031
GCIEV
2036
IEINN
2041
WRSFI
2046
PSKAV
2051
KNYHI
2056
NNCRS
2061
QGFML
2066
SPTAS
2071
FVDAS
2076
DVTQG
2081
VDTMW
2086
TSVSP
2091
SVAAP
2096
SVCQQ
2101
DVCHN
2106
GGTCH
2111
AIFLS
2116
SGIVS
2121
FQCDC
2126
PLHFT
2131
GRFCE
2136
KDAGL
2141
FFPSF
2146
NGNSY
2151
LELPF
2156
LKFVL
2161
EKEHN
2166
RTVTI
2171
YLTIK
2176
TNSLN
2181
GTILY
2186
SNGNN
2191
CGKQF
2196
LHLFL
2201
VEGRP
2206
SVKYG
2211
CGNSQ
2216
NILTV
2221
SANYS
2226
INTNA
2231
FTPIT
2236
IRYTT
2241
PVGSP
2246
GVVCM
2251
IEMTA
2256
DGKPP
2261
VQKKD
2266
TEISH
2271
ASQAY
2276
FESMF
2281
LGHIP
2286
ANVQI
2291
HKKAG
2296
PVYGF
2301
RGCIL
2306
DLQVN
2311
NKEFF
2316
IIDEA
2321
RHGKN
2326
IENCH
2331
VPWCA
2336
HHLCR
2341
NNGTC
2346
ISDNE
2351
NLFCE
2356
CPRLY
2361
SGKLC
2366
QFASC
2371
ENNPC
2376
GNGAT
2381
CVPKS
2386
GTDIV
2391
CLCPY
2396
GRSGP
2401
LCTDA
2406
INITQ
2411
PRFSG
2416
TDAFG
2421
YTSFL
2426
AYSRI
2431
SDISF
2436
HYEFH
2441
LKFQL
2446
ANNHS
2451
ALQNN
2456
LIFFT
2461
GQKGH
2466
GLNGD
2471
DFLAV
2476
GLLNG
2481
SVVYS
2486
YNLGS
2491
GIASI
2496
RSEPL
2501
NLSLG
2506
VHTVH
2511
LGKFF
2516
QEGWL
2521
KVDDH
2526
KNKSI
2531
IAPGR
2536
LVGLN
2541
VFSQF
2546
YVGGY
2551
SEYTP
2556
DLLPN
2561
GADFK
2566
NGFQG
2571
CIFTL
2576
QVRTE
2581
KDGHF
2586
RGLGN
2591
PEGHP
2596
NAGRS
2601
VGQCH
2606
ASPCS
2611
LMKCG
2616
NGGTC
2621
IESGT
2626
SVYCN
2631
CTTGW
2636
KGSFC
2641
TETVS
2646
TCDPE
2651
HDPPH
2656
HCSRG
2661
ATCIS
2666
LPHGY
2671
TCFCP
2676
LGTTG
2681
IYCEQ
2686
ALSIS
2691
DPSFR
2696
SNELS
2701
WMSFA
2706
SFHVR
2711
KKTHI
2716
QLQFQ
2721
PLAAD
2726
GILFY
2731
AAQHL
2736
KAQSG
2741
DFLCI
2746
SLVNS
2751
SVQLR
2756
YNLGD
2761
RTIIL
2766
ETLQK
2771
VTING
2776
STWHI
2781
IKAGR
2786
VGAEG
2791
YLDLD
2796
GINVT
2801
EKAST
2806
KMSSL
2811
DTNTD
2816
FYIGG
2821
VSSLN
2826
LVNPM
2831
AIENE
2836
PVGFQ
2841
GCIRQ
2846
VIINN
2851
QELQL
2856
TEFGA
2861
KGGSN
2866
VGDCD
2871
GTACG
2876
YNTCR
2881
NGGEC
2886
TVNGT
2891
TFSCR
2896
CLPDW
2901
AGNTC
2906
NQSVS
2911
CLNNL
2916
CLHQS
2921
LCIPD
2926
QSFSY
2931
SCLCT
2936
LGWVG
2941
RYCEN
2946
KTSFS
2951
TAKFM
2956
GNSYI
2961
KYIDP
2966
NYRMR
2971
NLQFT
2976
TISLN
2981
FSTTK
2986
TEGLI
2991
VWMGI
2996
AQNEE
3001
NDFLA
3006
IGLHN
3011
QTLKI
3016
AVNLG
3021
ERISV
3026
PMSYN
3031
NGTFC
3036
CNKWH
3041
HVVVI
3046
QNQTL
3051
IKAYI
3056
NNSLI
3061
LSEDI
3066
DPHKN
3071
FVALN
3076
YDGIC
3081
YLGGF
3086
EYGRK
3091
VNIVT
3096
QEIFK
3101
TNFVG
3106
KIKDV
3111
VFFQE
3116
PKNIE
3121
LIKLE
3126
GYNVY
3131
DGDEQ
3136
NEVT
3141
Mutation Information
DNA mutation:
c.G4027A
Peptide Range:
1331 ~ 1355
Mut AA position:
1343 (13 in Wild Type peptide)
Alignment
Wild Type:
"RELSAKHSLLSSADVSSSRFLNFGI
||||||||||||.||||||||||||
Mutant:
RELSAKHSLLSSTDVSSSRFLNFGI"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) EYS
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
RELSAKHSLLSSTDVSSSRFLNFGI
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT