Immunogenicity 3758

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
DNAH5
Transcript ID
uc003jfc.2
HLA INFO
A*29:02
TCR INFO

No TCR info found!

T cell Tumor cell A*29:02
sequence
Full length protein sequence (792 aa)
MRLVN
1
EMYQT
6
SLRQF
11
LGLFD
16
LSLAR
21
SVKSP
26
ITSKR
31
IANII
36
EHMTY
41
EVYKY
46
AARGL
51
YEEHK
56
FLFTL
61
LLTLK
66
IDIQR
71
NRVKH
76
EEFLT
81
LIKGG
86
ASLDL
91
KACPP
96
KPSKW
101
ILDIT
106
WLNLV
111
ELSKL
116
RQFSD
121
VLDQI
126
SRNEK
131
MWKIW
136
FDKEN
141
PEEEP
146
LPNAY
151
DKSLD
156
CFRRL
161
LLIRS
166
WCPDR
171
TIAQA
176
RKYIV
181
DSMGE
186
KYAEG
191
VILDL
196
EKTWE
201
ESDPR
206
TPLIC
211
LLSMG
216
SDPTD
221
SIIAL
226
GKRLK
231
IETRY
236
VSMGQ
241
GQEVH
246
ARKLL
251
QQTMA
256
NGGWA
261
LLQNC
266
HLGLD
271
FMDEL
276
MDIII
281
ETELV
286
HDAFR
291
LWMTT
296
EAHKQ
301
FPITL
306
LQMSI
311
KFAND
316
PPQGL
321
RAGLK
326
RTYSG
331
VSQDL
336
LDVSS
341
GSQWK
346
PMLYA
351
VAFLH
356
STVQE
361
RRKFG
366
ALGWN
371
IPYEF
376
NQADF
381
NATVQ
386
FIQNH
391
LDDMD
396
VKKGV
401
SWTTI
406
RYMIG
411
EIQYG
416
GRVTD
421
DYDKR
426
LLNTF
431
AKVWF
436
SENMF
441
GPDFS
446
FYQGY
451
NIPKC
456
STVDN
461
YLQYI
466
QSLPA
471
YDSPE
476
VFGLH
481
PNADI
486
TYQSK
491
LAKDV
496
LDTIL
501
GIQPK
506
DTSGG
511
GDETR
516
EAVVA
521
RLADD
526
MLEKL
531
PPDYV
536
PFEVK
541
ERLQK
546
MGPFQ
551
PMNIF
556
LRQEI
561
DRMQR
566
VLSLV
571
RSTLT
576
ELKLA
581
IDGTI
586
IMSEN
591
LRDAL
596
DCMFD
601
ARIPA
606
WWKKA
611
SWISS
616
TLGFW
621
FTELI
626
ERNSQ
631
FTSWV
636
FNGRP
641
HCFWM
646
TGFFN
651
PQGFL
656
TAMRQ
661
EITRA
666
NKGWA
671
LDNMV
676
LCNEV
681
TKWMK
686
DDISA
691
PPTEG
696
VYVYG
701
LYLEG
706
AGWDK
711
RNMKL
716
IESKP
721
KVLFE
726
LMPVI
731
RIYAE
736
NNTLR
741
DPRFY
746
SCPIY
751
KKPVR
756
TDLNY
761
IAAVD
766
LRTAQ
771
TPEHW
776
VLRGV
781
ALLCD
786
VK
791
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 25
Mut AA position:
13 (13 in Wild Type peptide)
Alignment
Wild Type:
"MRLVNEMYQTSLRQFLGLFDLSLAR
||||||||||||.||||||||||||
Mutant:
MRLVNEMYQTSLCQFLGLFDLSLAR"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) DNAH5

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay