Immunogenicity 3767

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
FOXD1
Transcript ID
uc003kcp.3
HLA INFO
DQA*05:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*05:01 DQB*02:02
sequence
Full length protein sequence (465 aa)
MTLST
1
EMSDA
6
SGLAE
11
ETDID
16
VVGEG
21
EDEED
26
EEEED
31
DDEGG
36
GGGPR
41
LAVPA
46
QRRRR
51
RRSYA
56
GEDEL
61
EDLEE
66
EEDDD
71
DILLA
76
PPAGG
81
SPAPP
86
GPAPA
91
AGAGA
96
GGGGG
101
GGGAG
106
GGGSA
111
GSGAK
116
NPLVK
121
PPYSY
126
IALIT
131
MAILQ
136
SPKKR
141
LTLSE
146
ICEFI
151
SGRFP
156
YYREK
161
FPAWQ
166
NSIRH
171
NLSLN
176
DCFVK
181
IPREP
186
GNPGK
191
GNYWT
196
LDPES
201
ADMFD
206
NGSFL
211
RRRKR
216
FKRQP
221
LLPPN
226
AAAAE
231
SLLLR
236
GAGAA
241
GGAGD
246
PAAAA
251
ALFPP
256
APPPP
261
PHAYG
266
YGPYG
271
CGYGL
276
QLPPY
281
APPSA
286
LFAAA
291
AAAAA
296
AAAFH
301
PHSPP
306
PPPPP
311
HGAAA
316
ELART
321
AFGYR
326
PHPLG
331
AALPG
336
PLPAS
341
AAKAG
346
GPGAS
351
ALARS
356
PFSIE
361
SIIGG
366
SLGPA
371
AAAAA
376
AAQAA
381
AAAQA
386
SPSPS
391
PVAAP
396
PAPGS
401
SGGGC
406
AAQAA
411
VGPAA
416
ALTRS
421
LVAAA
426
AAAAS
431
SVSSS
436
AALGT
441
LHQGT
446
ALSSV
451
ENFTA
456
RISNC
461
Mutation Information
DNA mutation:
None
Peptide Range:
238 ~ 262
Mut AA position:
250 (13 in Wild Type peptide)
Alignment
Wild Type:
"LLRGAGAAGGAGDPAAAAALFPPAP
||||||||||||.||||||||||||
Mutant:
LLRGAGAAGGAGAPAAAAALFPPAP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) FOXD1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay