Immunogenicity 377
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
CLSTN2
Transcript ID
uc003etn.3
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (955 aa)
MLPGR
1
LCWVP
6
LLLAL
11
GVGSG
16
SGGGG
21
DSRQR
26
RLLAA
31
KVNKH
36
KPWIE
41
TSYHG
46
VITEN
51
NDTVI
56
LDPPL
61
VALDK
66
DAPVP
71
FAGEI
76
CAFKI
81
HGQEL
86
PFEAV
91
VLNKT
96
SGEGR
101
LRAKS
106
PIDCE
111
LQKEY
116
TFIIQ
121
AYDCG
126
AGPHE
131
TAWKK
136
SHKAV
141
VHIQV
146
KDVNE
151
FAPTF
156
KEPAY
161
KAVVT
166
EGKIY
171
DSILQ
176
VEAID
181
EDCSP
186
QYSQI
191
CNYEI
196
VTTDV
201
PFAID
206
RNGNI
211
RNTEK
216
LSYDK
221
QHQYE
226
ILVTA
231
YDCGQ
236
KPAAQ
241
DTLVQ
246
VDVKP
251
VCKPG
256
WQDWT
261
KRIEY
266
QPGSG
271
SMPLF
276
PSIHL
281
ETCDG
286
AVSSL
291
QIVTE
296
LQTNY
301
IGKGC
306
DRETY
311
SEKSL
316
QKLCG
321
ASSGI
326
IDLLP
331
SPSAA
336
TNWTA
341
GLLVD
346
SSEMI
351
FKFDG
356
RQGAK
361
VPDGI
366
VPKNL
371
TDQFT
376
ITMWM
381
KHGPS
386
PGVRA
391
EKETI
396
LCNSD
401
KTEMN
406
RHHYA
411
LYVHN
416
CRLVF
421
LLRKD
426
FDQAD
431
TFRPA
436
EFHWK
441
LDQIC
446
DKEWH
451
YYVIN
456
VEFPV
461
VTLYM
466
DGATY
471
EPYLV
476
TNDWP
481
IHPSH
486
IAMQL
491
TVGAC
496
WQGGE
501
VTKPQ
506
FAQFF
511
HGSLA
516
SLTIR
521
PGKME
526
SQKVI
531
SCLQA
536
CKEGL
541
DINSL
546
ESLGQ
551
GIKYH
556
FNPSQ
561
SILVM
566
EGDDI
571
GNINR
576
ALQKV
581
SYINS
586
RQFPT
591
AGVRR
596
LKVSS
601
KVQCF
606
GEDVC
611
ISIPE
616
VDAYV
621
MVLQA
626
IEPRI
631
TLRGT
636
DHFWR
641
PAAQF
646
ESARG
651
VTLFP
656
DIKIV
661
STFAK
666
TEAPG
671
DVKTT
676
DPKSE
681
VLEEM
686
LHNLD
691
FCDIL
696
VIGGD
701
LDPRQ
706
ECLEL
711
NHSEL
716
HQRHL
721
DATNS
726
TAGYS
731
IYGVG
736
SMSRY
741
EQVLH
746
HIRYR
751
NWRPA
756
SLEAR
761
RFRIK
766
CSELN
771
GRYTS
776
NEFNL
781
EVSIL
786
HEDQV
791
SDKEH
796
VNHLI
801
VQPPF
806
LQSVH
811
HPESR
816
SSIQH
821
SSVVP
826
SIATV
831
VIIIS
836
VCMLV
841
FVVAM
846
GVYRV
851
RIAHQ
856
HFIQE
861
TEAAK
866
ESEMD
871
WDDSA
876
LTITV
881
NPMEK
886
HEGPG
891
HGEDE
896
TEGEE
901
EEEAE
906
EEMSS
911
SSGSD
916
DSEEE
921
EEEEG
926
MGRGR
931
HGQNG
936
ARQAQ
941
LEWDD
946
STLPY
951
Mutation Information
DNA mutation:
c.G2231A
Peptide Range:
732 ~ 756
Mut AA position:
744 (13 in Wild Type peptide)
Alignment
Wild Type:
"AGYSIYGVGSMSRYEQVLHHIRYRN
||||||||||||.||||||||||||
Mutant:
AGYSIYGVGSMSHYEQVLHHIRYRN"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) CLSTN2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
AGYSIYGVGSMSHYEQVLHHIRYRN
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT