Immunogenicity 380
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
HCN1
Transcript ID
uc003jok.3
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (890 aa)
MEGGG
1
KPNSS
6
SNSRD
11
DGNSV
16
FPAKA
21
SATGA
26
GPAAA
31
EKRLG
36
TPPGG
41
GGAGA
46
KEHGN
51
SVCFK
56
VDGGG
61
GGGGG
66
GGGGE
71
EPAGG
76
FEDAE
81
GPRRQ
86
YGFMQ
91
RQFTS
96
MLQPG
101
VNKFS
106
LRMFG
111
SQKAV
116
EKEQE
121
RVKTA
126
GFWII
131
HPYSD
136
FRFYW
141
DLIML
146
IMMVG
151
NLVII
156
PVGIT
161
FFTEQ
166
TTTPW
171
IIFNV
176
ASDTV
181
FLLDL
186
IMNFR
191
TGTVN
196
EDSSE
201
IILDP
206
KVIKM
211
NYLKS
216
WFVVD
221
FISSI
226
PVDYI
231
FLIVE
236
KGMDS
241
EVYKT
246
ARALR
251
IVRFT
256
KILSL
261
LRLLR
266
LSRLI
271
RYIHQ
276
WEEIF
281
HMTYD
286
LASAV
291
VRIFN
296
LIGMM
301
LLLCH
306
WDGCL
311
QFLVP
316
LLQDF
321
PPDCW
326
VSLNE
331
MVNDS
336
WGKQY
341
SYALF
346
KAMSH
351
MLCIG
356
YGAQA
361
PVSMS
366
DLWIT
371
MLSMI
376
VGATC
381
YAMFV
386
GHATA
391
LIQSL
396
DSSRR
401
QYQEK
406
YKQVE
411
QYMSF
416
HKLPA
421
DMRQK
426
IHDYY
431
EHRYQ
436
GKIFD
441
EENIL
446
NELND
451
PLREE
456
IVNFN
461
CRKLV
466
ATMPL
471
FANAD
476
PNFVT
481
AMLSK
486
LRFEV
491
FQPGD
496
YIIRE
501
GAVGK
506
KMYFI
511
QHGVA
516
GVITK
521
SSKEM
526
KLTDG
531
SYFGE
536
ICLLT
541
KGRRT
546
ASVRA
551
DTYCR
556
LYSLS
561
VDNFN
566
EVLEE
571
YPMMR
576
RAFET
581
VAIDR
586
LDRIG
591
KKNSI
596
LLQKF
601
QKDLN
606
TGVFN
611
NQENE
616
ILKQI
621
VKHDR
626
EMVQA
631
IAPIN
636
YPQMT
641
TLNST
646
SSTTT
651
PTSRM
656
RTQSP
661
PVYTA
666
TSLSH
671
SNLHS
676
PSPST
681
QTPQP
686
SAILS
691
PCSYT
696
TAVCS
701
PPVQS
706
PLAAR
711
TFHYA
716
SPTAS
721
QLSLM
726
QQQPQ
731
QQVQQ
736
SQPPQ
741
TQPQQ
746
PSPQP
751
QTPGS
756
STPKN
761
EVHKS
766
TQALH
771
NTNLT
776
REVRP
781
LSASQ
786
PSLPH
791
EVSTL
796
ISRPH
801
PTVGE
806
SLASI
811
PQPVT
816
AVPGT
821
GLQAG
826
GRSTV
831
PQRVT
836
LFRQM
841
SSGAI
846
PPNRG
851
VPPAP
856
PPPAA
861
ALPRE
866
SSSVL
871
NTDPD
876
AEKPR
881
FASNL
886
Mutation Information
DNA mutation:
c.C2227A
Peptide Range:
731 ~ 755
Mut AA position:
743 (13 in Wild Type peptide)
Alignment
Wild Type:
"QQQPQQQVQQSQPPQTQPQQPSPQP
||||||||||||.||||||||||||
Mutant:
QQQPQQQVQQSQTPQTQPQQPSPQP"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) HCN1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
QQQPQQQVQQSQTPQTQPQQPSPQP
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT