Immunogenicity 3807

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
GCM2
Transcript ID
uc003mzn.4
HLA INFO
C*12:03
TCR INFO

No TCR info found!

T cell Tumor cell C*12:03
sequence
Full length protein sequence (506 aa)
MPAAA
1
VQEAV
6
GVCSY
11
GMQLS
16
WDIND
21
PQMPQ
26
ELALF
31
DQFRE
36
WPDGY
41
VRFIY
46
SSDEK
51
KAQRH
56
LSGWA
61
MRNTN
66
NHNGH
71
ILKKS
76
CLGVV
81
VCTQA
86
CTLPD
91
GSRLQ
96
LRPAI
101
CDKAR
106
LKQQK
111
KACPN
116
CHSAL
121
ELIPC
126
RGHSG
131
YPVTN
136
FWRLD
141
GNAIF
146
FQAKG
151
VHDHP
156
RPESK
161
SETEA
166
RRSAI
171
KRQMA
176
SFYQP
181
QKKRI
186
RESEA
191
EENQD
196
SSGHF
201
SNIPP
206
LENPE
211
DFDIV
216
TETSF
221
PIPGQ
226
PCPSF
231
PKSDV
236
YKATC
241
DLATF
246
QGDKM
251
PPFQK
256
YSSPR
261
IYLPR
266
PPCSY
271
ELANP
276
GYTNS
281
SPYPT
286
LYKDS
291
TSIPN
296
DTDWV
301
HLNTL
306
QCNVN
311
SYSSY
316
ERSFD
321
FTNKQ
326
HGWKP
331
ALGKP
336
SLVER
341
TNHGQ
346
FQAMA
351
TRPYY
356
NPELP
361
CRYLT
366
TPPPG
371
APALQ
376
TVITT
381
TTKVS
386
YQAYQ
391
PPAMK
396
YSDSV
401
REVKS
406
LSSCN
411
YAPED
416
TGMSV
421
YPEPW
426
GPPVT
431
VTRAA
436
SPSGP
441
PPMKI
446
AGDCR
451
AIRPT
456
VAIPH
461
EPVSS
466
RTDEA
471
ETWDV
476
CLSGL
481
GSAVS
486
YSDRV
491
GPFFT
496
YNNED
501
F
506
Mutation Information
DNA mutation:
None
Peptide Range:
80 ~ 104
Mut AA position:
92 (13 in Wild Type peptide)
Alignment
Wild Type:
"SCLGVVVCTQACTLPDGSRLQLRPA
||||||||||||.||||||||||||
Mutant:
SCLGVVVCTQACPLPDGSRLQLRPA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GCM2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay