Immunogenicity 3846

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
ORC3
Transcript ID
uc011dzm.2
HLA INFO
DQA*02:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:02
sequence
Full length protein sequence (553 aa)
MATSS
1
MSKGC
6
FVFKP
11
NSKKR
16
KISLP
21
IEDYF
26
NKGKN
31
EPEDS
36
KLRFE
41
TYQLI
46
WQQMK
51
SENER
56
LQEEL
61
NKNLF
66
DNLIE
71
FLQKS
76
HSGFQ
81
KNSRD
86
LGGQI
91
KLREI
96
PTAAL
101
VLGVN
106
VTDHD
111
LTFGS
116
LTEAL
121
QNNVT
126
PYVVS
131
LQAKD
136
CPDMK
141
HFLQK
146
LISQL
151
MDCCV
156
DIKSK
161
EEESV
166
HVTQR
171
KTHYS
176
MDSLS
181
SWYMT
186
VTQKT
191
DPKML
196
SKKRT
201
TSSQW
206
QSPPV
211
VVILK
216
DMESF
221
ATKVL
226
QDFII
231
ISSQH
236
LHEFP
241
LILIF
246
GIATS
251
PIIIH
256
RLLPH
261
AVSSL
266
LCIEL
271
FQSLS
276
CKEHL
281
TTVLD
286
KLLLT
291
TQFPF
296
KINEK
301
VLQVL
306
TNIFL
311
YHDFS
316
VQNFI
321
KGLQL
326
SLLEH
331
FYSQP
336
LSVLC
341
CNLPE
346
AKRRI
351
NFLSN
356
NQCEN
361
IRRLP
366
SFRRY
371
VEKQA
376
SEKQV
381
ALLTN
386
ERYLK
391
EETQL
396
LLENL
401
HVYHM
406
NYFLV
411
LRCLH
416
KFTSS
421
LPKYP
426
LGRQI
431
RELYC
436
TCLEK
441
NIWDS
446
EEYAS
451
VLQLL
456
RMLAK
461
DELMT
466
ILEKC
471
FKVFK
476
SYCEN
481
HLGST
486
AKRIE
491
EFLAQ
496
FQSLD
501
AETKE
506
EEDAS
511
GSQPK
516
GLQKT
521
DLYHL
526
QKVRS
531
LSSLP
536
AASCD
541
TPFFQ
546
FVL
551
Mutation Information
DNA mutation:
None
Peptide Range:
99 ~ 123
Mut AA position:
111 (13 in Wild Type peptide)
Alignment
Wild Type:
"EIPTAALVLGVNVTDHDLTFGSLTE
||||||||||||.||||||||||||
Mutant:
EIPTAALVLGVNITDHDLTFGSLTE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ORC3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay