Immunogenicity 3860

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
AK9
Transcript ID
uc011eas.1
HLA INFO
A*01:01
TCR INFO

No TCR info found!

T cell Tumor cell A*01:01
sequence
Full length protein sequence (296 aa)
MVNKY
1
MQTYL
6
ERIKA
11
ELLSR
16
LGEFE
21
QFCPV
26
SLAES
31
QELFD
36
CSATD
41
SLEFA
46
AEFRG
51
HYYKM
56
SSQEK
61
LNKFL
66
ENPEL
71
YVPPL
76
APHPL
81
PSADM
86
IPKRL
91
TLSEL
96
KSRFP
101
KCAEL
106
QGYCP
111
VTYKD
116
GNQRY
121
EALVP
126
GSINY
131
ALEYH
136
NRIYI
141
CENKE
146
KLQKF
151
LRSPL
156
KYWEQ
161
KLPHK
166
LPPLR
171
EPILL
176
TSLPL
181
PGYLE
186
QGIAT
191
SLIKA
196
MNAAG
201
CLKPK
206
FPFLS
211
IRRSA
216
LLYIA
221
LHLKA
226
FNPKG
231
SEYTR
236
KKYKK
241
KMEQF
246
MESCE
251
LITYL
256
GAKMT
261
RKYKE
266
PQFRA
271
IDFDH
276
KLKTF
281
LSLRN
286
IDPIN
291
G
296
Mutation Information
DNA mutation:
None
Peptide Range:
234 ~ 258
Mut AA position:
246 (13 in Wild Type peptide)
Alignment
Wild Type:
"KGSEYTRKKYKKKMEQFMESCELIT
||||||||||||.||||||||||||
Mutant:
KGSEYTRKKYKKNMEQFMESCELIT"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) AK9

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay