Immunogenicity 3880

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TMEM181
Transcript ID
uc010kjr.1
HLA INFO
A*01:01
TCR INFO

No TCR info found!

T cell Tumor cell A*01:01
sequence
Full length protein sequence (365 aa)
MTATT
1
GPKVI
6
QTSAA
11
NFSLN
16
NSKKL
21
KPIQI
26
LSNPL
31
STYNQ
36
QLWLT
41
CVVEL
46
DQSKE
51
TSIKT
56
SFPMT
61
VKVDG
66
VAQDG
71
TTMYI
76
HNKVH
81
NRTRT
86
LTCAG
91
KCAEI
96
IVAHL
101
GYLNY
106
TQYTV
111
IVGFE
116
HLKLP
121
IKGMN
126
FTWKT
131
YNPAF
136
SRLEI
141
WFRFF
146
FVVLT
151
FIVTC
156
LFAHS
161
LRKFS
166
MRDWG
171
IEQKW
176
MSVLL
181
PLLLL
186
YNDPF
191
FPLSF
196
LVNSW
201
LPGML
206
DDLFQ
211
SMFLC
216
ALLLF
221
WLCVY
226
HGIRV
231
QGERK
236
CLTFY
241
LPKFF
246
IVGLL
251
WLASV
256
TLGIW
261
QTVNE
266
LHDPM
271
YQYRV
276
DTGNF
281
QGMKV
286
FFMVV
291
AAVYI
296
LYLLF
301
LIVRA
306
CSELR
311
HMPYV
316
DLRLK
321
FLTAL
326
TFVVL
331
VISIA
336
ILYLR
341
FGAQV
346
LQDNF
351
VAELS
356
THYQN
361
Mutation Information
DNA mutation:
None
Peptide Range:
237 ~ 261
Mut AA position:
249 (13 in Wild Type peptide)
Alignment
Wild Type:
"GERKCLTFYLPKFFIVGLLWLASVT
||||||||||||.||||||||||||
Mutant:
GERKCLTFYLPKLFIVGLLWLASVT"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TMEM181

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay