Immunogenicity 39
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
KIF23
Transcript ID
uc010ukc.2
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (974 aa)
MKSAR
1
AKTPR
6
KPTVK
11
KGSQT
16
NLKDP
21
VGVYC
26
RVRPL
31
GFPDQ
36
ECCIE
41
VINNT
46
TVQLH
51
TPEGY
56
RLNRN
61
GDYKE
66
TQYSF
71
KQVFG
76
THTTQ
81
KELFD
86
VVANP
91
LVNDL
96
IHGKN
101
GLLFT
106
YGVTG
111
SGKTH
116
TMTGS
121
PGEGG
126
LLPRC
131
LDMIF
136
NSIGS
141
FQAKR
146
YVFKS
151
NDRNS
156
MDIQC
161
EVDAL
166
LERQK
171
REAMP
176
NPKTS
181
SSKRQ
186
VDPEF
191
ADMIT
196
VQEFC
201
KAEEV
206
DEDSV
211
YGVFV
216
SYIEI
221
YNNYI
226
YDLLE
231
EVPFD
236
PIKPK
241
WNSCS
246
TPMRN
251
TDFVP
256
PQSKL
261
LREDK
266
NHNMY
271
VAGCT
276
EVEVK
281
STEEA
286
FEVFW
291
RGQKK
296
RRIAN
301
THLNR
306
ESSRS
311
HSVFN
316
IKLVQ
321
APLDA
326
DGDNV
331
LQEKE
336
QITIS
341
QLSLV
346
DLAGS
351
ERTNR
356
TRAEG
361
NRLRE
366
AGNIN
371
QSLMT
376
LRTCM
381
DVLRE
386
NQMYG
391
TNKMV
396
PYRDS
401
KLTHL
406
FKNYF
411
DGEGK
416
VRMIV
421
CVNPK
426
AEDYE
431
ENLQV
436
MRFAE
441
VTQEV
446
EVARP
451
VDKAI
456
CGLTP
461
GRRYR
466
NQPRG
471
PVGNE
476
PLVTD
481
VVLQS
486
FPPLP
491
SCEIL
496
DINDE
501
QTLPR
506
LIEAL
511
EKRHN
516
LRQMM
521
IDEFN
526
KQSNA
531
FKALL
536
QEFDN
541
AVLSK
546
ENHMQ
551
GKLNE
556
KEKMI
561
SGQKL
566
EIERL
571
EKKNK
576
TLEYK
581
IEILE
586
KTTTI
591
YEEDK
596
RNLQQ
601
ELETQ
606
NQKLQ
611
RQFSD
616
KRRLE
621
ARLQG
626
MVTET
631
TMKWE
636
KECER
641
RVAAK
646
QLEMQ
651
NKLWV
656
KDEKL
661
KQLKA
666
IVTEP
671
KTEKP
676
ERPSR
681
ERDRE
686
KVTQR
691
SVSPS
696
PVPLS
701
SNYIA
706
QISNG
711
QQLMS
716
QPQLH
721
RRSNS
726
CSSIS
731
VASCI
736
SEWEQ
741
KIPTY
746
NTPLK
751
VTSIA
756
RRRQQ
761
EPGQS
766
KTCIV
771
SDRRR
776
GMYWT
781
EGREV
786
VPTFR
791
NEIEI
796
EEDHC
801
GRLLF
806
QPDQN
811
APPIR
816
LRHRR
821
SRSAG
826
DRWVD
831
HKPAS
836
NMQTE
841
TVMQP
846
HVPHA
851
ITVSV
856
ANEKA
861
LAKCE
866
KYMLT
871
HQELA
876
SDGEI
881
ETKLI
886
KGDIY
891
KTRGG
896
GQSVQ
901
FTDIE
906
TLKQE
911
SPNGS
916
RKRRS
921
STVAP
926
AQPDG
931
AESEW
936
TDVET
941
RCSVA
946
VEMRA
951
GSQLG
956
PGYQH
961
HAQPK
966
RKKP
971
Mutation Information
DNA mutation:
c.G1956T
Peptide Range:
941 ~ 965
Mut AA position:
None (13 in Wild Type peptide)
Alignment
Wild Type:
"TDVETRCSVAVEMRAGSQLGPGYQH
||||||||||||.||||||||||||
Mutant:
TDVETRCSVAVEIRAGSQLGPGYQH"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) KIF23
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
TDVETRCSVAVEIRAGSQLGPGYQH
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT