Immunogenicity 3900

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
FAM120B
Transcript ID
uc003qxp.3
HLA INFO
B*52:01
TCR INFO

No TCR info found!

T cell Tumor cell B*52:01
sequence
Full length protein sequence (910 aa)
MGVRG
1
LQGFV
6
GSTCP
11
HICTV
16
VNFKE
21
LAEHH
26
RSKYP
31
GCTPT
36
IVVDA
41
MCCLR
46
YWYTP
51
ESWIC
56
GGQWR
61
EYFSA
66
LRDFV
71
KTFTA
76
AGIKL
81
IFFFD
86
GMVEQ
91
DKRDE
96
WVKRR
101
LKNNR
106
EISRI
111
FHYIK
116
SHKEQ
121
PGRNM
126
FFIPS
131
GLAVF
136
TRFAL
141
KTLGQ
146
ETLCS
151
LQEAD
156
YEVAS
161
YGLQH
166
NCLGI
171
LGEDT
176
DYLIY
181
DTCPY
186
FSISE
191
LCLES
196
LDTVM
201
LCREK
206
LCESL
211
GLCVA
216
DLPLL
221
ACLLG
226
NDIIP
231
EGMFE
236
SFRYK
241
CLSSY
246
TSVKE
251
NFDKK
256
GNIIL
261
AVSDH
266
ISKVL
271
YLYQG
276
EKKLE
281
EILPL
286
GPNKA
291
LFYKG
296
MASYL
301
LPGQK
306
SPWFF
311
QKPKG
316
VITLD
321
KQVIS
326
TSSDA
331
ESREE
336
VPMCS
341
DAESR
346
QEVPM
351
CTGPE
356
SRREV
361
PVYTD
366
SEPRQ
371
EVPMC
376
SDPEP
381
RQEVP
386
TCTGP
391
ESRRE
396
VPMCS
401
DPEPR
406
QEVPM
411
CTGPE
416
ARQEV
421
PMYTD
426
SEPRQ
431
EVPMY
436
TDSEP
441
RQEVP
446
MYTGS
451
EPRQE
456
VPMYT
461
GPESR
466
QEVPM
471
YTGPE
476
SRQEV
481
LIRTD
486
PESRQ
491
EIMCT
496
GHESK
501
QEVPI
506
CTDPI
511
SKQED
516
SMCTH
521
AEINQ
526
KLPVA
531
TDFEF
536
KLEAL
541
MCTNP
546
EIKQE
551
DPTNV
556
GPEVK
561
QQVTM
566
VSDTE
571
ILKVA
576
RTHHV
581
QAESY
586
LVYNI
591
MSSGE
596
IECSN
601
TLEDE
606
LDQAL
611
PSQAF
616
IYRPI
621
RQRVY
626
SLLLE
631
DCQDV
636
TSTCL
641
AVKEW
646
FVYPG
651
NPLRH
656
PDLVR
661
PLQMT
666
IPGGT
671
PSLKI
676
LWLNQ
681
EPEIQ
686
VRRLD
691
TLLAC
696
FNLSS
701
SREEL
706
QAVES
711
PFQAL
716
CCLLI
721
YLFVQ
726
VDTLC
731
LEDLH
736
AFIAQ
741
ALCLQ
746
GKSTS
751
QLVNL
756
QPDYI
761
NPRAV
766
QLGSL
771
LVRGL
776
TTLVL
781
VNSAC
786
GFPWK
791
TSDFM
796
PWNVF
801
DGKLF
806
HQKYL
811
QSEKG
816
YAVEV
821
LLEQN
826
RSRLT
831
KFHNL
836
KAVVC
841
KACMK
846
ENRRI
851
TGRAH
856
WGSHH
861
AGRWG
866
RQGSS
871
YHRTG
876
SGYSR
881
SSQGQ
886
PWRDQ
891
GPGSR
896
QYEHD
901
QWRRY
906
Mutation Information
DNA mutation:
None
Peptide Range:
409 ~ 433
Mut AA position:
421 (13 in Wild Type peptide)
Alignment
Wild Type:
"PRQEVPMCTGPEARQEVPMYTDSEP
||||||||||||.||||||||||||
Mutant:
PRQEVPMCTGPESRQEVPMYTDSEP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) FAM120B

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay