Immunogenicity 3919

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
SCIN
Transcript ID
uc003sso.4
HLA INFO
A*11:01
TCR INFO

No TCR info found!

T cell Tumor cell A*11:01
sequence
Full length protein sequence (468 aa)
MAKLY
1
MVSDA
6
SGSMR
11
VTVVA
16
EENPF
21
SMAML
26
LSEEC
31
FILDH
36
GAAKQ
41
IFVWK
46
GKDAN
51
PQERK
56
AAMKT
61
AEEFL
66
QQMNY
71
SKNTQ
76
IQVLP
81
EGGET
86
PIFKQ
91
FFKDW
96
RDKDQ
101
SDGFG
106
KVYVT
111
EKVAQ
116
IKQIP
121
FDASK
126
LHSSP
131
QMAAQ
136
HNMVD
141
DGSGK
146
VEIWR
151
VENNG
156
RIQVD
161
QNSYG
166
EFYGG
171
DCYII
176
LYTYP
181
RGQII
186
YTWQG
191
ANATR
196
DELTT
201
SAFLT
206
VQLDR
211
SLGGQ
216
AVQIR
221
VSQGK
226
EPVHL
231
LSLFK
236
DKPLI
241
IYKNG
246
TSKKG
251
GQAPA
256
PPTRL
261
FQVRR
266
NLASI
271
TRIVE
276
VDVDA
281
NSLNS
286
NDVFV
291
LKLPQ
296
NSGYI
301
WVGKG
306
ASQEE
311
EKGAE
316
YVASV
321
LKCKT
326
LRIQE
331
GEEPE
336
EFWNS
341
LGGKK
346
DYQTS
351
PLLET
356
QAEDH
361
PPRLY
366
GCSNK
371
TGRFV
376
IEEIP
381
GEFTQ
386
DDLAE
391
DDVML
396
LDAWE
401
QIFIW
406
IGKDA
411
NEVEK
416
KESLK
421
SAKMY
426
LETDP
431
SGRDK
436
RTPIV
441
IIKQG
446
HEPPT
451
FTGWF
456
LGWDS
461
SKW
466
Mutation Information
DNA mutation:
None
Peptide Range:
28 ~ 52
Mut AA position:
40 (13 in Wild Type peptide)
Alignment
Wild Type:
"AMLLSEECFILDHGAAKQIFVWKGK
||||||||||||.||||||||||||
Mutant:
AMLLSEECFILDLGAAKQIFVWKGK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SCIN

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay