Immunogenicity 393
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
KSR2
Transcript ID
uc001two.2
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (921 aa)
MIDLS
1
ISNLE
6
GLRTK
11
CATSN
16
DLTQK
21
EIRTL
26
ESKLV
31
KYFSR
36
QLSCK
41
KKVAL
46
QERNA
51
ELDGF
56
PQLRH
61
WFRIV
66
DVRKE
71
VLEEI
76
SPGQL
81
SLEDL
86
LEMTD
91
EQVCE
96
TVEKY
101
GANRE
106
ECARL
111
NASLS
116
CLRNV
121
HMSGG
126
NLSKQ
131
DWTIQ
136
WPTTE
141
TGKEN
146
NPVCP
151
PEPTP
156
WIRTH
161
LSQSP
166
RVPSK
171
CVQHY
176
CHTSP
181
TPGAP
186
VYTHV
191
DRLTV
196
DAYPG
201
LCPPP
206
PLESG
211
HRSLP
216
PSPRQ
221
RHAVR
226
TPPRT
231
PNIVT
236
TVTPP
241
GTPPM
246
RKKNK
251
LKPPG
256
TPPPS
261
SRKLI
266
HLIPG
271
FTALH
276
RSKSH
281
EFQLG
286
HRVDE
291
AHTPK
296
AKKKS
301
KPLNL
306
KIHSS
311
VGSCE
316
NIPSQ
321
QRSPL
326
LSERS
331
LRSFF
336
VGHAP
341
FLPST
346
PPVHT
351
EANFS
356
ANTLS
361
VPRWS
366
PQIPR
371
RDLGN
376
SIKHR
381
FSTKY
386
WMSQT
391
CTVCG
396
KGMLF
401
GLKCK
406
NCKLK
411
CHNKC
416
TKEAP
421
PCHLL
426
IIHRG
431
DPARL
436
VRTES
441
VPCDI
446
NNPLR
451
KPPRY
456
SDLHI
461
SQTLP
466
KTNKI
471
NKDHI
476
PVPYQ
481
PDSSS
486
NPSST
491
TSSTP
496
SSPAP
501
PLPPS
506
ATPPS
511
PLHPS
516
PQCTR
521
QQKNF
526
NLPAS
531
HYYKY
536
KQQFI
541
FPDVV
546
PVPET
551
PTRAP
556
QVILH
561
PVTSN
566
PILEG
571
NPLLQ
576
IEVEP
581
TSENE
586
EVHDE
591
AEESE
596
DDFEE
601
MNLSL
606
LSARS
611
FPRKA
616
SQTSI
621
FLQEW
626
DIPFE
631
QLEIG
636
ELIGK
641
GRFGQ
646
VYHGR
651
WHGEV
656
AIRLI
661
DIERD
666
NEDQL
671
KAFKR
676
EVMAY
681
RQTRH
686
ENVVL
691
FMGAC
696
MSPPH
701
LAIIT
706
SLCKG
711
RTLYS
716
VVRDA
721
KIVLD
726
VNKTR
731
QIAQE
736
IVKGM
741
GYLHA
746
KGILH
751
KDLKS
756
KNVFY
761
DNGKV
766
VITDF
771
GLFSI
776
SGVLQ
781
AGRRE
786
DKLRI
791
QNGWL
796
CHLAP
801
EIIRQ
806
LSPDT
811
EEDKL
816
PFSKH
821
SDVFA
826
LGTIW
831
YELHA
836
REWPF
841
KTQPA
846
EAIIW
851
QMGTG
856
MKPNL
861
SQIGM
866
GKEIS
871
DILLF
876
CWAFE
881
QEERP
886
TFTKL
891
MDMLE
896
KLPKR
901
NRRLS
906
HPGHF
911
WKSAE
916
L
921
Mutation Information
DNA mutation:
c.C740T
Peptide Range:
235 ~ 259
Mut AA position:
247 (13 in Wild Type peptide)
Alignment
Wild Type:
"TPNIVTTVTPPGTPPMRKKNKLKPP
||||||||||||.||||||||||||
Mutant:
TPNIVTTVTPPGMPPMRKKNKLKPP"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) KSR2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
TPNIVTTVTPPGMPPMRKKNKLKPP
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT