Immunogenicity 396
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
CIT
Transcript ID
None
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (2069 aa)
MLKFK
1
YGARN
6
PLDAG
11
AAEPI
16
ASRAS
21
RLNLF
26
FQGKP
31
PFMTQ
36
QQMSP
41
LSREG
46
ILDAL
51
FVLFE
56
ECSQP
61
ALMKI
66
KHVSN
71
FVRKY
76
SDTIA
81
ELQEL
86
QPSAK
91
DFEVR
96
SLVGC
101
GHFAE
106
VQVVR
111
EKATG
116
DIYAM
121
KVMKK
126
KALLA
131
QEQVS
136
FFEEE
141
RNILS
146
RSTSP
151
WIPQL
156
QYAFQ
161
DKNHL
166
YLVME
171
YQPGG
176
DLLSL
181
LNRYE
186
DQLDE
191
NLIQF
196
YLAEL
201
ILAVH
206
SVHLM
211
GYVHR
216
DIKPE
221
NILVD
226
RTGHI
231
KLVDF
236
GSAAK
241
MNSNK
246
MVNAK
251
LPIGT
256
PDYMA
261
PEVLT
266
VMNGD
271
GKGTY
276
GLDCD
281
WWSVG
286
VIAYE
291
MIYGR
296
SPFAE
301
GTSAR
306
TFNNI
311
MNFQR
316
FLKFP
321
DDPKV
326
SSDFL
331
DLIQS
336
LLCGQ
341
KERLK
346
FEGLC
351
CHPFF
356
SKIDW
361
NNIRN
366
SPPPF
371
VPTLK
376
SDDDT
381
SNFDE
386
PEKNS
391
WVSSS
396
PCQLS
401
PSGFS
406
GEELP
411
FVGFS
416
YSKAL
421
GILGR
426
SESVV
431
SGLDS
436
PAKTS
441
SMEKK
446
LLIKS
451
KELQD
456
SQDKC
461
HKMEQ
466
EMTRL
471
HRRVS
476
EVEAV
481
LSQKE
486
VELKA
491
SETQR
496
SLLEQ
501
DLATY
506
ITECS
511
SLKRS
516
LEQAR
521
MEVSQ
526
EDDKA
531
LQLLH
536
DIREQ
541
SRKLQ
546
EIKEQ
551
EYQAQ
556
VEEMR
561
LMMNQ
566
LEEDL
571
VSARR
576
RSDLY
581
ESELR
586
ESRLA
591
AEEFK
596
RKATE
601
CQHKL
606
LKAKD
611
QGKPE
616
VGEYA
621
KLEKI
626
NAEQQ
631
LKIQE
636
LQEKL
641
EKAVK
646
ASTEA
651
TELLQ
656
NIRQA
661
KERAE
666
RELEK
671
LQNRE
676
DSSEG
681
IRKKL
686
VEAEE
691
RRHSL
696
ENKVK
701
RLETM
706
ERREN
711
RLKDD
716
IQTKS
721
QQIQQ
726
MADKI
731
LELEE
736
KHREA
741
QVSAQ
746
HLEVH
751
LKQKE
756
QHYEE
761
KIKVL
766
DNQIK
771
KDLAD
776
KETLE
781
NMMQR
786
HEEEA
791
HEKGK
796
ILSEQ
801
KAMIN
806
AMDSK
811
IRSLE
816
QRIVE
821
LSEAN
826
KLAAN
831
SSLFT
836
QRNMK
841
AQEEM
846
ISELR
851
QQKFY
856
LETQA
861
GKLEA
866
QNRKL
871
EEQLE
876
KISHQ
881
DHSDK
886
NRLLE
891
LETRL
896
REVSL
901
EHEEQ
906
KLELK
911
RQLTE
916
LQLSL
921
QERES
926
QLTAL
931
QAARA
936
ALESQ
941
LRQAK
946
TELEE
951
TTAEA
956
EEEIQ
961
ALTAH
966
RDEIQ
971
RKFDA
976
LRNSC
981
TVITD
986
LEEQL
991
NQLTE
996
DNAEL
1001
NNQNF
1006
YLSKQ
1011
LDEAS
1016
GANDE
1021
IVQLR
1026
SEVDH
1031
LRREI
1036
TEREM
1041
QLTSQ
1046
KQTME
1051
ALKTT
1056
CTMLE
1061
EQVMD
1066
LEALN
1071
DELLE
1076
KERQW
1081
EAWRS
1086
VLGDE
1091
KSQFE
1096
CRVRE
1101
LQRML
1106
DTEKQ
1111
SRARA
1116
DQRIT
1121
ESRQV
1126
VELAV
1131
KEHKA
1136
EILAL
1141
QQALK
1146
EQKLK
1151
AESLS
1156
DKLND
1161
LEKKH
1166
AMLEM
1171
NARSL
1176
QQKLE
1181
TEREL
1186
KQRLL
1191
EEQAK
1196
LQQQM
1201
DLQKN
1206
HIFRL
1211
TQGLQ
1216
EALDR
1221
ADLLK
1226
TERSD
1231
LEYQL
1236
ENIQV
1241
LYSHE
1246
KVKME
1251
GTISQ
1256
QTKLI
1261
DFLQA
1266
KMDQP
1271
AKKKK
1276
VPLQY
1281
NELKL
1286
ALEKE
1291
KARCA
1296
ELEEA
1301
LQKTR
1306
IELRS
1311
AREEA
1316
AHRKA
1321
TDHPH
1326
PSTPA
1331
TARQQ
1336
IAMSA
1341
IVRSP
1346
EHQPS
1351
AMSLL
1356
APPSS
1361
RRKES
1366
STPEE
1371
FSRRL
1376
KERMH
1381
HNIPH
1386
RFNVG
1391
LNMRA
1396
TKCAV
1401
CLDTV
1406
HFGRQ
1411
ASKCL
1416
ECQVM
1421
CHPKC
1426
STCLP
1431
ATCGL
1436
PAEYA
1441
THFTE
1446
AFCRD
1451
KMNSP
1456
GLQTK
1461
EPSSS
1466
LHLEG
1471
WMKVP
1476
RNNKR
1481
GQQGW
1486
DRKYI
1491
VLEGS
1496
KVLIY
1501
DNEAR
1506
EAGQR
1511
PVEEF
1516
ELCLP
1521
DGDVS
1526
IHGAV
1531
GASEL
1536
ANTAK
1541
ADVPY
1546
ILKME
1551
SHPHT
1556
TCWPG
1561
RTLYL
1566
LAPSF
1571
PDKQR
1576
WVTAL
1581
ESVVA
1586
GGRVS
1591
REKAE
1596
ADAAR
1601
DCVSY
1606
ELLPA
1611
WVQKL
1616
LGNSL
1621
LKLEG
1626
DDRLD
1631
MNCTL
1636
PFSDQ
1641
VVLVG
1646
TEEGL
1651
YALNV
1656
LKNSL
1661
THVPG
1666
IGAVF
1671
QIYII
1676
KDLEK
1681
LLMIA
1686
GEERA
1691
LCLVD
1696
VKKVK
1701
QSLAQ
1706
SHLPA
1711
QPDIS
1716
PNIFE
1721
AVKGC
1726
HLFGA
1731
GKIEN
1736
GLCIC
1741
AAMPS
1746
KVVIL
1751
RYNEN
1756
LSKYC
1761
IRKEI
1766
ETSEP
1771
CSCIH
1776
FTNYS
1781
ILIGT
1786
NKFYE
1791
IDMKQ
1796
YTLEE
1801
FLDKN
1806
DHSLA
1811
PAVFA
1816
ASSNS
1821
FPVSI
1826
VQVNS
1831
AGQRE
1836
EYLLC
1841
FHEFG
1846
VFVDS
1851
YGRRS
1856
RTDDL
1861
KWSRL
1866
PLAFA
1871
YREPY
1876
LFVTH
1881
FNSLE
1886
VIEIQ
1891
ARSSA
1896
GTPAR
1901
AYLDI
1906
PNPRY
1911
LGPAI
1916
SSGAI
1921
YLASS
1926
YQDKL
1931
RVICC
1936
KGNLV
1941
KESGT
1946
EHHRG
1951
PSTSR
1956
SSPNK
1961
RGPPT
1966
YNEHI
1971
TKRVA
1976
SSPAP
1981
PEGPS
1986
HPREP
1991
STPHR
1996
YREGR
2001
TELRR
2006
DKSPG
2011
RPLER
2016
EKSPG
2021
RMLST
2026
RRERS
2031
PGRLF
2036
EDSSR
2041
GRLPA
2046
GAVRT
2051
PLSQV
2056
NKVWD
2061
QSSV
2066
Mutation Information
DNA mutation:
None
Peptide Range:
2055 ~ 2078
Mut AA position:
2056 (2 in Wild Type peptide)
Alignment
Wild Type:
"----------TPLSQVNKV-----
|.|||||||
Mutant:
RGRLPAGAVRTLLSQVNKVWDQSS"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) CIT
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay