Immunogenicity 3986
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
ZAN
Transcript ID
uc003uwk.3
HLA INFO
A*26:01
TCR INFO
No TCR info found!
Full length protein sequence (2721 aa)
MVPPV
1
WTLLL
6
LVGAA
11
LFRKE
16
KPPDQ
21
KLVVR
26
SSRDN
31
YVLTQ
36
CDFED
41
DAKPL
46
CDWSQ
51
VSADD
56
EDWVR
61
ASGPS
66
PTGST
71
GAPGG
76
YPNGE
81
GSYLH
86
MESNS
91
FHRGG
96
VARLL
101
SPDLW
106
EQGPL
111
CVHFA
116
HHMFG
121
LSWGA
126
QLRLL
131
LLSGE
136
EGRRP
141
DVLWK
146
HWNTQ
151
RPSWM
156
LTTVT
161
VPAGF
166
TLPTR
171
LMFEG
176
TRGST
181
AYLDI
186
ALDAL
191
SIRRG
196
SCNRV
201
CMMQT
206
CSFDI
211
PNDLC
216
DWTWI
221
PTASG
226
AKWTQ
231
KKGSS
236
GKPGV
241
GPDGD
246
FSSPG
251
SGCYM
256
LLDPK
261
NARPG
266
QKAVL
271
LSPVS
276
LSSGC
281
LSFSF
286
HYILR
291
GQSPG
296
AALHI
301
YASVL
306
GSIRK
311
HTLFS
316
GQPGP
321
NWQAV
326
SVNYT
331
AVGRI
336
QFAVV
341
GVFGK
346
TPEPA
351
VAVDA
356
TSIAP
361
CGEGF
366
PQCDF
371
EDNAH
376
PFCDW
381
VQTSG
386
DGGHW
391
ALGHK
396
NGPVH
401
GMGPA
406
GGFPN
411
AGGHY
416
IYLEA
421
DEFSQ
426
AGQSV
431
RLVSR
436
PFCAP
441
GDICV
446
EFAYH
451
MYGLG
456
EGTML
461
ELLLG
466
SPAGS
471
PPIPL
476
WKRVG
481
SQRPY
486
WQNTS
491
VTVPS
496
GHQQP
501
MQLIF
506
KGIQG
511
SNTAS
516
VVAMG
521
FILIN
526
PGTCP
531
VKVLP
536
ELPPV
541
SPVSS
546
TGPSE
551
TTGLT
556
ENPTI
561
STKKP
566
TVSIE
571
KPSVT
576
TEKPT
581
VPKEK
586
PTIPT
591
EKPTI
596
STEKP
601
TIPSE
606
KPNMP
611
SEKPT
616
IPSEK
621
PTILT
626
EKPTI
631
PSEKP
636
TIPSE
641
KPTIS
646
TEKPT
651
VPTEE
656
PTTPT
661
EETTT
666
SMEEP
671
VIPTE
676
KPSIP
681
TEKPS
686
IPTEK
691
PTISM
696
EETII
701
STEKP
706
TISPE
711
KPTIP
716
TEKPT
721
IPTEK
726
STISP
731
EKPTT
736
PTEKP
741
TIPTE
746
KPTIS
751
PEKPT
756
TPTEK
761
PTISP
766
EKLTI
771
PTEKP
776
TIPTE
781
KPTIP
786
TEKPT
791
ISTEE
796
PTTPT
801
EETTI
806
STEKP
811
SIPME
816
KPTLP
821
TEETT
826
TSVEE
831
TTIST
836
EKLTI
841
PMEKP
846
TISTE
851
KPTIP
856
TEKPT
861
ISPEK
866
LTIPT
871
EKLTI
876
PTEKP
881
TIPIE
886
ETTIS
891
TEKLT
896
IPTEK
901
PTISP
906
EKPTI
911
STEKP
916
TIPTE
921
KPTIP
926
TEETT
931
ISTEK
936
LTIPT
941
EKPTI
946
SPEKL
951
TIPTE
956
KPTIS
961
TEKPT
966
IPTEK
971
LTIPT
976
EKPTI
981
PTEKP
986
TIPTE
991
KLTAL
996
RPPHP
1001
SPTAT
1006
GLAAL
1011
VMSPH
1016
APSTP
1021
MTSVI
1026
LGTTT
1031
TSRSS
1036
TERCP
1041
PNARY
1046
ESCAC
1051
PASCK
1056
SPRPS
1061
CGPLC
1066
REGCV
1071
CNPGF
1076
LFSDN
1081
HCIQA
1086
SSCNC
1091
FYNND
1096
YYEPG
1101
AEWFS
1106
PNCTE
1111
HCRCW
1116
PGSRV
1121
ECQIS
1126
QCGTH
1131
TVCQL
1136
KNGQY
1141
GCHPY
1146
AGTAT
1151
CLVYG
1156
DPHYV
1161
TFDGR
1166
HFGFM
1171
GKCTY
1176
ILAQP
1181
CGNST
1186
DPFFR
1191
VTAKN
1196
EEQGQ
1201
EGVSC
1206
LSKVY
1211
VTLPE
1216
STVTL
1221
LKGRR
1226
TLVGG
1231
QQVTL
1236
PAIPS
1241
KGVFL
1246
GASGR
1251
FVELQ
1256
TEFGL
1261
RVRWD
1266
GDQQL
1271
YVTVS
1276
STYSG
1281
KLCGL
1286
CGNYD
1291
GNSDN
1296
DHLKL
1301
DGSPA
1306
GDKEE
1311
LGNSW
1316
QTDQD
1321
EDQEC
1326
QKYQV
1331
VNSPS
1336
CDSSL
1341
QSSMS
1346
GPGFC
1351
GRLVD
1356
THGPF
1361
ETCLL
1366
HVKAA
1371
SFFDS
1376
CMLDM
1381
CGFQG
1386
LQHLL
1391
CTHMS
1396
TMTTT
1401
CQDAG
1406
HAVKP
1411
WREPH
1416
FCPMA
1421
CPPNS
1426
KYSLC
1431
AKPCP
1436
DTCHS
1441
GFSGM
1446
FCSDR
1451
CVEAC
1456
ECNPG
1461
FVLSG
1466
LECIP
1471
RSQCG
1476
CLHPA
1481
GSYFK
1486
VGERW
1491
YKPGC
1496
KELCV
1501
CESNN
1506
RIRCQ
1511
PWRCR
1516
AQEFC
1521
GQQDG
1526
IYGCH
1531
AQGAA
1536
TCTAS
1541
GDPHY
1546
LTFDG
1551
ALHHF
1556
MGTCT
1561
YVLTR
1566
PCWSR
1571
SQDSY
1576
FVVSA
1581
TNENR
1586
GGILE
1591
VSYIK
1596
AVHVT
1601
VFDLS
1606
ISLLR
1611
GCKVM
1616
LNGHR
1621
VALPV
1626
WLAQG
1631
RVTIR
1636
LSSNL
1641
VLLYT
1646
NFGLQ
1651
VRYDG
1656
SHLVE
1661
VTVPS
1666
SYGGQ
1671
LCGLC
1676
GNYNN
1681
NSLDD
1686
NLRPD
1691
RKLAG
1696
DSMQL
1701
GAAWK
1706
LPESS
1711
EPGCF
1716
LVGGK
1721
PSSCQ
1726
ENSMA
1731
DAWNK
1736
NCAIL
1741
INPQG
1746
PFSQC
1751
HQVVP
1756
PQSSF
1761
ASCVH
1766
GQCGT
1771
KGDTT
1776
ALCRS
1781
LQAYA
1786
SLCAQ
1791
AGQAP
1796
AWRNR
1801
TFCPM
1806
RCPPG
1811
SSYSP
1816
CSSPC
1821
PDTCS
1826
SINNP
1831
RDCPK
1836
ALPCA
1841
ESCEC
1846
QKGHI
1851
LSGTS
1856
CVPLG
1861
QCGCT
1866
DPAGS
1871
YHPVG
1876
ERWYT
1881
ENTCT
1886
RLCTC
1891
SVHNN
1896
ITCFQ
1901
STCKP
1906
NQICW
1911
ALDGL
1916
LRCRA
1921
SGVGV
1926
CQLPG
1931
ESHYV
1936
SFDGS
1941
NHSIP
1946
DACTL
1951
VLVKV
1956
CHPAM
1961
ALPFF
1966
KISAK
1971
HEKEE
1976
GGTEA
1981
FRLHE
1986
VYIDI
1991
YDAQV
1996
TLQKG
2001
HRVLI
2006
NSKQV
2011
TLPAI
2016
SQIPG
2021
VSVKS
2026
SSIYS
2031
IVNIK
2036
IGVQV
2041
KFDGN
2046
HLLEI
2051
EIPTT
2056
YYGKV
2061
CGMCG
2066
NFNDE
2071
EEDEL
2076
MMPSD
2081
EVANS
2086
DSEFV
2091
NSWKD
2096
KDIDP
2101
SCQSL
2106
LVDEQ
2111
QIPAE
2116
QQENP
2121
SGNCR
2126
AADLR
2131
RAREK
2136
CEAAL
2141
RAPVW
2146
AQCAS
2151
RIDLT
2156
PFLVD
2161
CANTL
2166
CEFGG
2171
LYQAL
2176
CQALQ
2181
AFGAT
2186
CQSQG
2191
LKPPL
2196
WRNSS
2201
FCPLE
2206
CPAYS
2211
SYTNC
2216
LPSCS
2221
PSCWD
2226
LDGRC
2231
EGAKV
2236
PSACA
2241
EGCIC
2246
QPGYV
2251
LSEDK
2256
CVPRS
2261
QCGCK
2266
DAHGG
2271
SIPLG
2276
KSWVS
2281
SGCTE
2286
KCVCT
2291
GGAIQ
2296
CGDFR
2301
CPSGS
2306
HCQLT
2311
SDNSN
2316
SNCVS
2321
DKSEQ
2326
CSVYG
2331
DPRYL
2336
TFDGF
2341
SYRLQ
2346
GRMTY
2351
VLIKT
2356
VDVLP
2361
EGVEP
2366
LLVEG
2371
RNKMD
2376
PPRSS
2381
IFLQE
2386
VITTV
2391
YGYKV
2396
QLQAG
2401
LELVV
2406
NNQKM
2411
AVPYR
2416
PNEHL
2421
RVTLW
2426
GQRLY
2431
LVTDF
2436
ELVVS
2441
FGGRK
2446
NAVIS
2451
LPSMY
2456
EGLVS
2461
GLCGN
2466
YDKNR
2471
KNDMM
2476
LPSGA
2481
LTQNL
2486
NTFGN
2491
SWEVK
2496
TEDAL
2501
LRFPR
2506
AIPAE
2511
EEGQG
2516
AELGL
2521
RTGLQ
2526
VSECS
2531
PEQLA
2536
SNSTQ
2541
ACRVL
2546
ADPQG
2551
PFAAC
2556
HQTVA
2561
PEPFQ
2566
EHCVL
2571
DLCSA
2576
QDPRE
2581
QEELR
2586
CQVLS
2591
GYAIL
2596
CQEAG
2601
AALAG
2606
WRDRT
2611
LCESP
2616
CLQNP
2621
CQNDG
2626
QCREQ
2631
GATFT
2636
CECEV
2641
GYGGG
2646
LCMEP
2651
RDAPP
2656
PRKPA
2661
SNLVA
2666
VLLGL
2671
LVPVV
2676
VVLLA
2681
VTREC
2686
IYRTR
2691
RKREK
2696
TQEGD
2701
RLARL
2706
VDTDT
2711
VLDCA
2716
C
2721
Mutation Information
DNA mutation:
None
Peptide Range:
749 ~ 773
Mut AA position:
761 (13 in Wild Type peptide)
Alignment
Wild Type:
"TEKPTISPEKPTTPTEKPTISPEKL
||||||||||||.||||||||||||
Mutant:
TEKPTISPEKPTIPTEKPTISPEKL"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) ZAN
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay