Immunogenicity 3989

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
SLC12A9
Transcript ID
uc003uwv.3
HLA INFO
DQA*02:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:02
sequence
Full length protein sequence (445 aa)
MFLIS
1
PGAAG
6
GSLLL
11
MGLLA
16
ALLTA
21
RGGPS
26
SWGYV
31
SQALL
36
FHQVR
41
KYLLR
46
LDVRK
51
DHVKF
56
WRPQL
61
LLLVG
66
NPRGA
71
LPLLR
76
LANQL
81
KKGGL
86
YVLGH
91
VTLGD
96
LDSLP
101
SDPVQ
106
PQYGA
111
WLSLV
116
DRAQV
121
KAFVD
126
LTLSP
131
SVRQG
136
AQHLL
141
RISGL
146
GGMKP
151
NTLVL
156
GFYDD
161
APPQD
166
HFLTD
171
PAFSE
176
PADST
181
REGSS
186
PALST
191
LFPPP
196
RAPGS
201
PRALN
206
PQDYV
211
ATVAD
216
ALKMN
221
KNVVL
226
ARASG
231
ALPPE
236
RLSRG
241
SGGTS
246
QLHHV
251
DVWPL
256
NLLRP
261
RGGPG
266
YVDVC
271
GLFLL
276
QMATI
281
LGMVP
286
AWHSA
291
RLRIF
296
LCLGP
301
REAPG
306
AAEGR
311
LRALL
316
SQLRI
321
RAEVQ
326
EVVWG
331
EGAGA
336
GEPEA
341
EEEGD
346
FVNSG
351
RGDAE
356
AEALA
361
RSANA
366
LVRAQ
371
QGRGT
376
GGGPG
381
GPEGG
386
DAEGP
391
ITALT
396
FLYLP
401
RPPAD
406
PARYP
411
RYLAL
416
LETLT
421
RDLGP
426
TLLVH
431
GVTPV
436
TCTDL
441
Mutation Information
DNA mutation:
None
Peptide Range:
357 ~ 381
Mut AA position:
369 (13 in Wild Type peptide)
Alignment
Wild Type:
"GDAEAEALARSANALVRAQQGRGTG
||||||||||||.||||||||||||
Mutant:
GDAEAEALARSASALVRAQQGRGTG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SLC12A9

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay