Immunogenicity 400
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
CRY1
Transcript ID
None
HLA INFO
B*27:02
TCR INFO
No TCR info found!
Full length protein sequence (632 aa)
MGVNA
1
VHWFR
6
KGLRL
11
HDNPA
16
LKECI
21
QGADT
26
IRCVY
31
ILDPW
36
FAGSS
41
NVGIN
46
RWRFL
51
LQCLE
56
DLDAN
61
LRKLN
66
SRLFV
71
IRGQP
76
ADVFP
81
RLFKE
86
WNITK
91
LSIEY
96
DSEPF
101
GKERD
106
AAIKK
111
LATEA
116
GVEVI
121
VRISH
126
TLYDL
131
DKIIE
136
LNGGQ
141
PPLTY
146
KRFQT
151
LISKM
156
EPLEI
161
PVETI
166
TSEVI
171
EKCTT
176
PLSDD
181
HDEKY
186
GVPSL
191
EELGF
196
DTDGL
201
SSAVW
206
PGGET
211
EALTR
216
LERHL
221
ERKAW
226
VANFE
231
RPRMN
236
ANSLL
241
ASPTG
246
LSPYL
251
RFGCL
256
SCRLF
261
YFKLT
266
DLYKK
271
VKKNS
276
SPPLS
281
LYGQL
286
LWREF
291
FYTAA
296
TNNPR
301
FDKME
306
GNPIC
311
VQIPW
316
DKNPE
321
ALAKW
326
AEGRT
331
GFPWI
336
DAIMT
341
QLRQE
346
GWIHH
351
LARHA
356
VACFL
361
TRGDL
366
WISWE
371
EGMKV
376
FEELL
381
LDADW
386
SINAG
391
SWMWL
396
SCSSF
401
FQQFF
406
HCYCP
411
VGFGR
416
RTDPN
421
GDYIR
426
RYLPV
431
LRGFP
436
AKYIY
441
DPWNA
446
PEGIQ
451
KVAKC
456
LIGVN
461
YPKPM
466
VNHAE
471
ASRLN
476
IERMK
481
QIYQQ
486
LSRYR
491
GLGLL
496
ASVPS
501
NPNGN
506
GGFMG
511
YSAEN
516
IPGCS
521
SSGSC
526
SQGSG
531
ILHYA
536
HGDSQ
541
QTHLL
546
KQGKN
551
EALEH
556
TVLFP
561
FPILN
566
IHFLN
571
VQEEA
576
PWALV
581
SVVGN
586
VLVRK
591
RTHRV
596
LVLKS
601
RDRAL
606
IRKHS
611
GGILL
616
QLKLV
621
GSSIL
626
FN
631
Mutation Information
DNA mutation:
None
Peptide Range:
67 ~ 89
Mut AA position:
71 (5 in Wild Type peptide)
Alignment
Wild Type:
"-------RKLNSRLFVI------
||||.|||||
Mutant:
EDLDANLRKLNFRLFVIRGQPAD"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) CRY1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
None
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay