Immunogenicity 4004

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
ING3
Transcript ID
uc003vjp.3
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (378 aa)
MLYLE
1
DYLEM
6
IEQLP
11
MDLRD
16
RFTEM
21
REMDL
26
QVQNA
31
MDQLE
36
QRVSE
41
FFMNA
46
KKNKP
51
EWREE
56
QMASI
61
KKDYY
66
KALED
71
ADEKV
76
QLANQ
81
IYDLV
86
DRHLR
91
KLDQE
96
LAKFK
101
MELEA
106
DNAGI
111
TEILE
116
RRSLE
121
LDTPS
126
QPVNN
131
HHAHS
136
HTPVE
141
KRKYN
146
PTSHH
151
TTTDH
156
IPEKK
161
FKSEA
166
LLSTL
171
TSDAS
176
KENTL
181
GCRNN
186
NSTAS
191
SNNAY
196
NVNSS
201
QPLGS
206
YNIGS
211
LSSGT
216
GAGAI
221
TMAAA
226
QAVQA
231
TAQMK
236
EGRRT
241
SSLKA
246
SYEAF
251
KNNDF
256
QLGKE
261
FSMAR
266
ETVGY
271
SSSSA
276
LMTTL
281
TQNAS
286
SSAAD
291
SRSGR
296
KSKNN
301
NKSSS
306
QQSSS
311
SSSSS
316
SLSSC
321
SSSST
326
VVQEI
331
SQQTT
336
VVPES
341
DSNSQ
346
VDWTY
351
DPNEP
356
RYCIC
361
NQVKV
366
CYIYK
371
SII
376
Mutation Information
DNA mutation:
None
Peptide Range:
34 ~ 58
Mut AA position:
46 (13 in Wild Type peptide)
Alignment
Wild Type:
"NAMDQLEQRVSEFFMNAKKNKPEWR
||||||||||||.||||||||||||
Mutant:
NAMDQLEQRVSELFMNAKKNKPEWR"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ING3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay