Immunogenicity 401
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
GRIN2B
Transcript ID
None
HLA INFO
B*41:02
TCR INFO
No TCR info found!
Full length protein sequence (1484 aa)
MKPRA
1
ECCSP
6
KFWLV
11
LAVLA
16
VSGSR
21
ARSQK
26
SPPSI
31
GIAVI
36
LVGTS
41
DEVAI
46
KDAHE
51
KDDFH
56
HLSVV
61
PRVEL
66
VAMNE
71
TDPKS
76
IITRI
81
CDLMS
86
DRKIQ
91
GVVFA
96
DDTDQ
101
EAIAQ
106
ILDFI
111
SAQTL
116
TPILG
121
IHGGS
126
SMIMA
131
DKDES
136
SMFFQ
141
FGPSI
146
EQQAS
151
VMLNI
156
MEEYD
161
WYIFS
166
IVTTY
171
FPGYQ
176
DFVNK
181
IRSTI
186
ENSFV
191
GWELE
196
EVLLL
201
DMSLD
206
DGDSK
211
IQNQL
216
KKLQS
221
PIILL
226
YCTKE
231
EATYI
236
FEVAN
241
SVGLT
246
GYGYT
251
WIVPS
256
LVAGD
261
TDTVP
266
AEFPT
271
GLISV
276
SYDEW
281
DYGLP
286
ARVRD
291
GIAII
296
TTAAS
301
DMLSE
306
HSFIP
311
EPKSS
316
CYNTH
321
EKRIY
326
QSNML
331
NRYLI
336
NVTFE
341
GRNLS
346
FSEDG
351
YQMHP
356
KLVII
361
LLNKE
366
RKWER
371
VGKWK
376
DKSLQ
381
MKYYV
386
WPRMC
391
PETEE
396
QEDDH
401
LSIVT
406
LEEAP
411
FVIVE
416
SVDPL
421
SGTCM
426
RNTVP
431
CQKRI
436
VTENK
441
TDEEP
446
GYIKK
451
CCKGF
456
CIDIL
461
KKISK
466
SVKFT
471
YDLYL
476
VTNGK
481
HGKKI
486
NGTWN
491
GMIGE
496
VVMKR
501
AYMAV
506
GSLTI
511
NEERS
516
EVVDF
521
SVPFI
526
ETGIS
531
VMVSR
536
SNGTV
541
SPSAF
546
LEPFS
551
ADVWV
556
MMFVM
561
LLIVS
566
AVAVF
571
VFEYF
576
SPVGY
581
NRCLA
586
DGREP
591
GGPSF
596
TIGKA
601
IWLLW
606
GLVFN
611
NSVPV
616
QNPKG
621
TTSKI
626
MVSVW
631
AFFAV
636
IFLAS
641
YTANL
646
AAFMI
651
QEEYV
656
DQVSG
661
LSDKK
666
FQRPN
671
DFSPP
676
FRFGT
681
VPNGS
686
TERNI
691
RNNYA
696
EMHAY
701
MGKFN
706
QRGVD
711
DALLS
716
LKTGK
721
LDAFI
726
YDAAV
731
LNYMA
736
GRDEG
741
CKLVT
746
IGSGK
751
VFAST
756
GYGIA
761
IQKDS
766
GWKRQ
771
VDLAI
776
LQLFG
781
DGEME
786
ELEAL
791
WLTGI
796
CHNEK
801
NEVMS
806
SQLDI
811
DNMAG
816
VFYML
821
GAAMA
826
LSLIT
831
FICEH
836
LFYWQ
841
FRHCF
846
MGVCS
851
GKPGM
856
VFSIS
861
RGIYS
866
CIHGV
871
AIEER
876
QSVMN
881
SPTAT
886
MNNTH
891
SNILR
896
LLRTA
901
KNMAN
906
LSGVN
911
GSPQS
916
ALDFI
921
RRESS
926
VYDIS
931
EHRRS
936
FTHSD
941
CKSYN
946
NPPCE
951
ENLFS
956
DYISE
961
VERTF
966
GNLQL
971
KDSNV
976
YQDHY
981
HHHHR
986
PHSIG
991
SASSI
996
DGLYD
1001
CDNPP
1006
FTTQS
1011
RSISK
1016
KPLDI
1021
GLPSS
1026
KHSQL
1031
SDLYG
1036
KFSFK
1041
SDRYS
1046
GHDDL
1051
IRSDV
1056
SDIST
1061
HTVTY
1066
GNIEG
1071
NAAKR
1076
RKQQY
1081
KDSLK
1086
KRPAS
1091
AKSRR
1096
EFDEI
1101
ELAYR
1106
RRPPR
1111
SPDHK
1116
RYFRD
1121
KEGLR
1126
DFYLD
1131
QFRTK
1136
ENSPH
1141
WEHVD
1146
LTDIY
1151
KERSD
1156
DFKRD
1161
SVSGG
1166
GPCTN
1171
RSHIK
1176
HGTGD
1181
KHGVV
1186
SGVPA
1191
PWEKN
1196
LTNVE
1201
WEDRS
1206
GGNFC
1211
RSCPS
1216
KLHNY
1221
STTVT
1226
GQNSG
1231
RQACI
1236
RCEAC
1241
KKAGN
1246
LYDIS
1251
EDNSL
1256
QELDQ
1261
PAAPV
1266
AVTSN
1271
ASTTK
1276
YPQSP
1281
TNSKA
1286
QKKNR
1291
NKLRR
1296
QHSYD
1301
TFVDL
1306
QKEEA
1311
ALAPR
1316
SVSLK
1321
DKGRF
1326
MDGSP
1331
YAHMF
1336
EMSAG
1341
ESTFA
1346
NNKSS
1351
VPTAG
1356
HHHHN
1361
NPGGG
1366
YMLSK
1371
SLYPD
1376
RVTQN
1381
PFIPT
1386
FGDDQ
1391
CLLHG
1396
SKSYF
1401
FRQPT
1406
VAGAS
1411
KARPD
1416
FRALV
1421
TNKPV
1426
VSALH
1431
GAVPA
1436
RFQKD
1441
ICIGN
1446
QSNPC
1451
VPNNK
1456
NPRAF
1461
NGSSN
1466
GHVYE
1471
KLSSI
1476
ESDV
1481
Mutation Information
DNA mutation:
None
Peptide Range:
1100 ~ 1118
Mut AA position:
1104 (5 in Wild Type peptide)
Alignment
Wild Type:
"-------REFDEIELA---
||||.||||
Mutant:
PASAKSRREFDKIELAYRR"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) GRIN2B
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
None
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay