Immunogenicity 4011

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
AKR1B15
Transcript ID
uc011kpr.2
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (344 aa)
MVLQM
1
EPQVN
6
STNNF
11
HQGPL
16
DQPVG
21
PLTGL
26
KSSLL
31
KDTTS
36
AGPLL
41
RPYPA
46
SLLGK
51
VKEAV
56
KVAID
61
AEYRH
66
IDCAY
71
FYENQ
76
HEVGE
81
AIQEK
86
IQEKA
91
VMRED
96
LFIVS
101
KVWPT
106
FFERP
111
LVRKA
116
FEKTL
121
KDLKL
126
SYLDV
131
YLIHW
136
PQGFK
141
TGDDF
146
FPKDD
151
KGNMI
156
SGKGT
161
FLDAW
166
EAMEE
171
LVDEG
176
LVKAL
181
GVSNF
186
NHFQI
191
ERLLN
196
KPGLK
201
YKPVT
206
NQVEC
211
HPYLT
216
QEKLI
221
QYCHS
226
KGITV
231
TAYSP
236
LGSPD
241
RPWAK
246
PEDPS
251
LLEDP
256
KIKEI
261
AAKHK
266
KTTAQ
271
VLIRF
276
HIQRN
281
VTVIP
286
KSMTP
291
AHIVE
296
NIQVF
301
DFKLS
306
DEEMA
311
TILSF
316
NRNWR
321
AFDFK
326
EFSHL
331
EDFPF
336
DAEY
341
Mutation Information
DNA mutation:
None
Peptide Range:
93 ~ 117
Mut AA position:
105 (13 in Wild Type peptide)
Alignment
Wild Type:
"EKAVMREDLFIVSKVWPTFFERPLV
||||||||||||.||||||||||||
Mutant:
EKAVMREDLFIVCKVWPTFFERPLV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) AKR1B15

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay