Immunogenicity 404
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
EEA1
Transcript ID
None
HLA INFO
A*66:01
TCR INFO
No TCR info found!
Full length protein sequence (1365 aa)
MKSLG
1
SADEL
6
FKHYE
11
AVHDA
16
GNDSG
21
HGGES
26
NLALK
31
RDDVT
36
LLRQE
41
VQDLQ
46
ASLKE
51
EKWYS
56
EELKK
61
ELEKY
66
QGLQQ
71
QEAKP
76
DGLVT
81
DSSAE
86
LQSLE
91
QQLEE
96
AQTEN
101
FNIKQ
106
MKDLF
111
EQKAA
116
QLATE
121
IADIK
126
SKYDE
131
ERSLR
136
EAAEQ
141
KVTRL
146
TEELN
151
KEATV
156
IQDLK
161
TELLQ
166
RPGIE
171
DVAVL
176
KKELV
181
QVQTL
186
MDNMT
191
LERER
196
ESEKL
201
KDECK
206
KLQSQ
211
YASSE
216
ATISQ
221
LRSEL
226
AKGPQ
231
EVAVY
236
VQELQ
241
KLKSS
246
VNELT
251
QKNQT
256
LTENL
261
LKKEQ
266
DYTKL
271
EEKHN
276
EESVS
281
KKNIQ
286
ATLHQ
291
KDLDC
296
QQLQS
301
RLSAS
306
ETSLH
311
RIHVE
316
LSEKG
321
EATQK
326
LKEEL
331
SEVET
336
KYQHL
341
KAEFK
346
QLQQQ
351
REEKE
356
QHGLQ
361
LQSEI
366
NQLHS
371
KLLET
376
ERQLG
381
EAHGR
386
LKEQR
391
QLSSE
396
KLMDK
401
EQQVA
406
DLQLK
411
LSRLE
416
EQLKE
421
KVTNS
426
TELQH
431
QLDKT
436
KQQHQ
441
EQQAL
446
QQSTT
451
AKLRE
456
AQNDL
461
EQVLR
466
QIGDK
471
DQKIQ
476
NLEAL
481
LQKSK
486
ENISL
491
LEKER
496
EDLYA
501
KIQAG
506
EGETA
511
VLNQL
516
QEKNH
521
TLQEQ
526
VTQLT
531
EKLKN
536
QSESH
541
KQAQE
546
NLHDQ
551
VQEQK
556
AHLRA
561
AQDRV
566
LSLET
571
SVNEL
576
NSQLN
581
ESKEK
586
VSQLD
591
IQIKA
596
KTELL
601
LSAEA
606
AKTAQ
611
RADLQ
616
NHLDT
621
AQNAL
626
QDKQQ
631
ELNKI
636
TTQLD
641
QVTAK
646
LQDKQ
651
EHCSQ
656
LESHL
661
KEYKE
666
KYLSL
671
EQKTE
676
ELEGQ
681
IKKLE
686
ADSLE
691
VKASK
696
EQALQ
701
DLQQQ
706
RQLNT
711
DLELR
716
ATELS
721
KQLEM
726
EKEIV
731
SSTRL
736
DLQKK
741
SEALE
746
SIKQK
751
LTKQE
756
EEKKI
761
LKQDF
766
ETLSQ
771
ETKIQ
776
HEELN
781
NRIQT
786
TVTEL
791
QKVKM
796
EKEAL
801
MTELS
806
TVKDK
811
LSKVS
816
DSLKN
821
SKSEF
826
EKENQ
831
KGKAA
836
ILDLE
841
KTCKE
846
LKHQL
851
QVQME
856
NTLKE
861
QKELK
866
KSLEK
871
EKEAS
876
HQLKL
881
ELNSM
886
QEQLI
891
QAQNT
896
LKQNE
901
KEEQQ
906
LQGNI
911
NELKQ
916
SSEQK
921
KKQIE
926
ALQGE
931
LKIAV
936
LQKTE
941
LENKL
946
QQQLT
951
QAAQE
956
LAAEK
961
EKISV
966
LQNNY
971
EKSQE
976
TFKQL
981
QSDFY
986
GRESE
991
LLATR
996
QDLKS
1001
VEEKL
1006
SLAQE
1011
DLISN
1016
RNQIG
1021
NQNKL
1026
IQELK
1031
TAKAT
1036
LEQDS
1041
AKKEQ
1046
QLQER
1051
CKALQ
1056
DIQKE
1061
KSLKE
1066
KELVN
1071
EKSKL
1076
AEIEE
1081
IKCRQ
1086
EKEIT
1091
KLNEE
1096
LKSHK
1101
LESIK
1106
EITNL
1111
KDAKQ
1116
LLIQQ
1121
KLELQ
1126
GKADS
1131
LKAAV
1136
EQEKR
1141
NQQIL
1146
KDQVK
1151
KEEEE
1156
LKKEF
1161
IEKEA
1166
KLHSE
1171
IKEKE
1176
VGMKK
1181
HEENE
1186
AKLTM
1191
QITAL
1196
NENLG
1201
TVKKE
1206
WQSSQ
1211
RRVSE
1216
LEKQT
1221
DDLRG
1226
EIAVL
1231
EATVQ
1236
NNQDE
1241
RRALL
1246
ERCLK
1251
GEGEI
1256
EKLQT
1261
KVLEL
1266
QRKLD
1271
NTTAA
1276
VQELG
1281
RENQS
1286
LQIKH
1291
TQALN
1296
RKWAE
1301
DNEVQ
1306
NCMAC
1311
GKGFS
1316
VTVRR
1321
HHCRQ
1326
CGNIF
1331
CAECS
1336
AKNAL
1341
TPSSK
1346
KPVRV
1351
CDACF
1356
NDLQG
1361
Mutation Information
DNA mutation:
None
Peptide Range:
1107 ~ 1126
Mut AA position:
1161 (9 in Wild Type peptide)
Alignment
Wild Type:
"----ESIKEITNL-------
||||||||.
Mutant:
SHKLESIKEITNFKDAKQLL"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) EEA1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay