Immunogenicity 405
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ZFYVE26
Transcript ID
None
HLA INFO
A*23:01
TCR INFO
No TCR info found!
Full length protein sequence (2545 aa)
MNHPF
1
GKEEA
6
ASQKQ
11
LFGFF
16
CECLR
21
RGEWE
26
LAQAC
31
VPQLQ
36
EGQGD
41
IPKRV
46
EDILQ
51
ALVVC
56
PNLLR
61
CGQDI
66
NPQRV
71
AWVWL
76
LVLEK
81
WLARE
86
KKLLP
91
VVFRR
96
KLEFL
101
LLSED
106
LQGDI
111
PENIL
116
EELYE
121
TLTQG
126
AVGHV
131
PDGNP
136
RRESW
141
TPRLS
146
SEAVS
151
VLWDL
156
LRQSP
161
QPAQA
166
LLELL
171
LEEDD
176
GTGLC
181
HWPLQ
186
NALVD
191
LIRKA
196
LRALQ
201
GPDSV
206
PPGVV
211
DAIYG
216
ALRTL
221
RCPAE
226
PLGVE
231
LHLLC
236
EELLE
241
ACRTE
246
GSPLR
251
EERLL
256
SCLLH
261
KASRG
266
LLSLY
271
GHTYA
276
EKVTE
281
KPPRA
286
TASGK
291
VSPDH
296
LDPER
301
AMLAL
306
FSNPN
311
PAEAW
316
KVAYF
321
YCLSN
326
NKHFL
331
EQILV
336
TALTL
341
LKEED
346
FPNLG
351
CLLDR
356
EFRPL
361
SCLLV
366
LLGWT
371
HCQSL
376
ESAKR
381
LLQTL
386
HRTQG
391
PGCDE
396
LLRDA
401
CDGLW
406
AHLEV
411
LEWCI
416
QQSSN
421
PIPKR
426
DLLYH
431
LHGGD
436
SHSVL
441
YTLHH
446
LTNLP
451
ALREE
456
DVLKL
461
LQKVP
466
AKDPQ
471
QEPDA
476
VDAPV
481
PEHLS
486
QCQNL
491
TLYQG
496
FCAMK
501
YAIYA
506
LCVNS
511
HQHSQ
516
CQDCK
521
DSLSE
526
DLASA
531
TEPAN
536
DSLSS
541
PGAAN
546
LFSTY
551
LARCQ
556
QYLCS
561
IPDSL
566
CLELL
571
ENIFS
576
LLLIT
581
SADLH
586
PEPHL
591
PEDYA
596
EDDDI
601
EGKSP
606
SGLRS
611
PSESP
616
QHIAH
621
PERKS
626
ERGSL
631
GVPKT
636
LAYTM
641
PSHVK
646
AEPKD
651
SYPGP
656
HRHSF
661
LDLKH
666
FTSGI
671
SGFLA
676
DEFAI
681
GAFLR
686
LLQEQ
691
LDEIS
696
SRSPP
701
EKPKQ
706
ESQSC
711
SGSRD
716
GLQSR
721
LHRLS
726
KVVSE
731
AQWRH
736
KVVTS
741
NHRSE
746
EQPSR
751
RYQPA
756
TRHPS
761
LRRGR
766
RTRRS
771
QADGR
776
DRGSN
781
PSLES
786
TSSEL
791
STSTS
796
EGSLS
801
AMSGR
806
NELHS
811
RLHPH
816
PQSSL
821
IPMMF
826
SPPES
831
LLASC
836
ILRGN
841
FAEAH
846
QVLFT
851
FNLKS
856
SPSSG
861
ELMFM
866
ERYQE
871
VIQEL
876
AQVEH
881
KIENQ
886
NSDAG
891
SSTIR
896
RTGSG
901
RSTLQ
906
AIGSA
911
AAAGM
916
VFYSI
921
SDVTD
926
KLLNT
931
SGDPI
936
PMLQE
941
DFWIS
946
TALVE
951
PTAPL
956
REVLE
961
DLSPP
966
AMAAF
971
DLACS
976
QCQLW
981
KTCKQ
986
LLETA
991
ERRLN
996
SSLER
1001
RGRRI
1006
DHVLL
1011
NADGI
1016
RGFPV
1021
VLQQI
1026
SKSLN
1031
YLLMS
1036
ASQTK
1041
SESVE
1046
EKGGG
1051
PPRCS
1056
ITELL
1061
QMCWP
1066
SLSED
1071
CVASH
1076
TTLSQ
1081
QLDQV
1086
LQSLR
1091
EALEL
1096
PEPRT
1101
PPLSS
1106
LVEQA
1111
AQKAP
1116
EAEAH
1121
PVQIQ
1126
TQLLQ
1131
KNLGK
1136
QTPSG
1141
SRQMD
1146
YLGTF
1151
FSYCS
1156
TLAAV
1161
LLQSL
1166
SSEPD
1171
HVEVK
1176
VGNPF
1181
VLLQQ
1186
SSSQL
1191
VSHLL
1196
FERQV
1201
PPERL
1206
AALLA
1211
QENLS
1216
LSVPQ
1221
VIVSC
1226
CCEPL
1231
ALCSS
1236
RQSQQ
1241
TSSLL
1246
TRLGT
1251
LAQLH
1256
ASHCL
1261
DDLPL
1266
STPSS
1271
PRTTE
1276
NPTLE
1281
RKPYS
1286
SPRDS
1291
SLPAL
1296
TSSAL
1301
AFLKS
1306
RSKLL
1311
ATVAC
1316
LGASP
1321
RLKVS
1326
KPSLS
1331
WKELR
1336
GRREV
1341
PLAAE
1346
QVARE
1351
CERLL
1356
EQFPL
1361
FEAFL
1366
LAAWE
1371
PLRGS
1376
LQQGQ
1381
SLAVN
1386
LCGWA
1391
SLSTV
1396
LLGLH
1401
SPIAL
1406
DVLSE
1411
AFEES
1416
LVARD
1421
WSRAL
1426
QLTEV
1431
YGRDV
1436
DDLSS
1441
IKDAV
1446
LSCAV
1451
ACDKE
1456
GWQYL
1461
FPVKD
1466
ASLRS
1471
RLALQ
1476
FVDRW
1481
PLESC
1486
LEILA
1491
YCISD
1496
TAVQE
1501
GLKCE
1506
LQRKL
1511
AELQV
1516
YQKIL
1521
GLQSP
1526
PVWCD
1531
WQTLR
1536
SCCVE
1541
DPSTV
1546
MNMIL
1551
EAQEY
1556
ELCEE
1561
WGCLY
1566
PIPRE
1571
HLISL
1576
HQKHL
1581
LHLLE
1586
RRDHD
1591
KALQL
1596
LRRIP
1601
DPTMC
1606
LEVTE
1611
QSLDQ
1616
HTSLA
1621
TSHFL
1626
ANYLT
1631
THFYG
1636
QLTAV
1641
RHREI
1646
QALYV
1651
GSKIL
1656
LTLPE
1661
QHRAS
1666
YSHLS
1671
SNPLF
1676
MLEQL
1681
LMNMK
1686
VDWAT
1691
VAVQT
1696
LQQLL
1701
VGQEI
1706
GFTMD
1711
EVDSL
1716
LSRYA
1721
EKALD
1726
FPYPQ
1731
REKRS
1736
AFSLS
1741
TDSVI
1746
HLQEI
1751
VHQAA
1756
DPETL
1761
PRSPS
1766
AEFSP
1771
AAPPG
1776
ISSIH
1781
SPSLR
1786
ERSFP
1791
PTQPS
1796
QEFVP
1801
PATPP
1806
ARHQW
1811
VPDET
1816
ESICM
1821
VCCRE
1826
HFTMF
1831
NRRHH
1836
CRRCG
1841
RLVCS
1846
SCSTK
1851
KMVVE
1856
GCREN
1861
PARVC
1866
DQCYS
1871
YCNKD
1876
VPEEP
1881
SEKPE
1886
ALDSS
1891
KNESP
1896
PYSFV
1901
VRVPK
1906
ADEVE
1911
WILDL
1916
KEEEN
1921
ELVRS
1926
EFYYE
1931
QAPSA
1936
SLCIA
1941
ILNLH
1946
RDSIA
1951
CGHQL
1956
IEHCC
1961
RLSKG
1966
LTNPE
1971
VDAGL
1976
LTDIM
1981
KQLLF
1986
SAKMM
1991
FVKAG
1996
QSQDL
2001
ALCDS
2006
YISKV
2011
DVLNI
2016
LVAAA
2021
YRHVP
2026
SLDQI
2031
LQPAA
2036
VTRLR
2041
NQLLE
2046
AEYYQ
2051
LGVEV
2056
STKTG
2061
LDTTG
2066
AWHAW
2071
GMACL
2076
KAGNL
2081
TAARE
2086
KFSRC
2091
LKPPF
2096
DLNQL
2101
NHGSR
2106
LVQDV
2111
VEYLE
2116
STVRP
2121
FVSLQ
2126
DDDYF
2131
ATLRE
2136
LEATL
2141
RTQSL
2146
SLAVI
2151
PEGKI
2156
MNNTY
2161
YQECL
2166
FYLHN
2171
YSTNL
2176
AIISF
2181
YVRHS
2186
CLREA
2191
LLHLL
2196
NKESP
2201
PEVFI
2206
EGIFQ
2211
PSYKS
2216
GKLHT
2221
LENLL
2226
ESIDP
2231
TLESW
2236
GKYLI
2241
AACQH
2246
LQKKN
2251
YYHIL
2256
YELQQ
2261
FMKDQ
2266
VRAAM
2271
TCIRF
2276
FSHKA
2281
KSYTE
2286
LGEKL
2291
SWLLK
2296
AKDHL
2301
KIYLQ
2306
ETSRS
2311
SGRKK
2316
TTFFR
2321
KKMTA
2326
ADVSR
2331
HMNTL
2336
QLQME
2341
VTRFL
2346
HRCES
2351
AGTSQ
2356
ITTLP
2361
LPTLF
2366
GNNHM
2371
KMDVA
2376
CKVML
2381
GGKNV
2386
EDGFG
2391
IAFRV
2396
LQDFQ
2401
LDAAM
2406
TYCRA
2411
ARQLV
2416
EKEKY
2421
SEIQQ
2426
LLKCV
2431
SESGM
2436
AAKSD
2441
GDTIL
2446
LNCLE
2451
AFKRI
2456
PPQEL
2461
EGLIQ
2466
AIHND
2471
DNKVR
2476
AYLIC
2481
CKLRS
2486
AYLIA
2491
VKQEH
2496
SRATA
2501
LVQQV
2506
QQAAK
2511
SSGDA
2516
VVQDI
2521
CAQWL
2526
LTSHP
2531
RGAHG
2536
PGSRK
2541
Mutation Information
DNA mutation:
None
Peptide Range:
544 ~ 569
Mut AA position:
544 (1 in Wild Type peptide)
Alignment
Wild Type:
"-----------SSPGAANLF------
.||||||||
Mutant:
ASATEPANDSLFSPGAANLFSTYLAR"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) ZFYVE26
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay