Immunogenicity 4054

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
XKR9
Transcript ID
uc010lze.3
HLA INFO
DQA*02:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:02
sequence
Full length protein sequence (373 aa)
MKYTK
1
QNFMM
6
SVLGI
11
IIYVT
16
DLIVD
21
IWVSV
26
RFFHE
31
GQYVF
36
SALAL
41
SFMLF
46
GTLVA
51
QCFSY
56
SWFKA
61
DLKKA
66
GQESQ
71
HCFLL
76
LHCLQ
81
GGVFT
86
RYWFA
91
LKRGY
96
HAAFK
101
YDSNT
106
SNFVE
111
EQIDL
116
HKEVI
121
DRVTD
126
LSMLR
131
LFETY
136
LEGCP
141
QLILQ
146
LYILL
151
EHGQA
156
NFSQY
161
AAIMV
166
SCCAI
171
SWSTV
176
DYQVA
181
LRKSL
186
PDKKL
191
LNGLC
196
PKITY
201
LFYKL
206
FTLLS
211
WMLSV
216
VLLLF
221
LNVKI
226
ALFLL
231
LFLWL
236
LGIIW
241
AFKNN
246
TQFCT
251
CISME
256
FLYRI
261
VVGFI
266
LIFTF
271
FNIKG
276
QNTKC
281
PMSCY
286
YIVRV
291
LGTLG
296
ILTVF
301
WVCPL
306
TIFNP
311
DYFIP
316
ISITI
321
VLTLL
326
LGILF
331
LIVYY
336
GSFHP
341
NRSAE
346
TKCDE
351
IDGKP
356
VLREC
361
RMRYF
366
LME
371
Mutation Information
DNA mutation:
None
Peptide Range:
290 ~ 314
Mut AA position:
302 (13 in Wild Type peptide)
Alignment
Wild Type:
"YYIVRVLGTLGILTVFWVCPLTIFN
||||||||||||.||||||||||||
Mutant:
YYIVRVLGTLGIMTVFWVCPLTIFN"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) XKR9

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay