Immunogenicity 4067

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
DENND3
Transcript ID
uc003yvz.1
HLA INFO
B*08:01
TCR INFO

No TCR info found!

T cell Tumor cell B*08:01
sequence
Full length protein sequence (502 aa)
MVLHR
1
QGWFL
6
LAWAV
11
ESLGS
16
PPQPR
21
APEQL
26
FCWQL
31
SSART
36
LKETR
41
AFPII
46
SVTFW
51
DVKNH
56
LNYEH
61
RVFNS
66
EEFLK
71
TRAPG
76
DHQFY
81
KQVLD
86
TYMFH
91
SFLKA
96
RLNRR
101
MDAFA
106
QMDLD
111
TQSEE
116
DRING
121
MLLSP
126
RRPTV
131
EKRAS
136
RKSSH
141
LHVTH
146
RRMVV
151
SMPNL
156
QDIAM
161
PELAP
166
RNSSL
171
RLTDT
176
AGCRG
181
SSAVL
186
NVTPK
191
SPYTF
196
KIPEI
201
HFPLE
206
SKCVQ
211
AYHAH
216
FVSML
221
SEAMC
226
FLAPD
231
NSLLL
236
ARYLY
241
LRGLV
246
YLMQG
251
QLLNA
256
LLDFQ
261
NLYKT
266
DIRIF
271
PTDLV
276
KRTVE
281
SMSAP
286
EWEGA
291
EQAPE
296
LMRLI
301
SEILD
306
KPHEA
311
SKLDD
316
HVKKF
321
KLPKK
326
HMQLG
331
DFMKR
336
VQESG
341
IVKDA
346
SIIHR
351
LFEAL
356
TVGQE
361
KQIDP
366
ETFKD
371
FYNCW
376
KETEA
381
EAQEV
386
SLPWL
391
VMEHL
396
DKNEC
401
VCKLS
406
SSVKT
411
NLGVG
416
KIAMT
421
QKRLF
426
LLTEG
431
RPGYL
436
EISTF
441
RNIEV
446
RTAQA
451
DGARP
456
HLCLG
461
DRWLE
466
WALSS
471
LPAMP
476
STSCS
481
PSADR
486
MPSCP
491
SVCSS
496
VK
501
Mutation Information
DNA mutation:
None
Peptide Range:
276 ~ 300
Mut AA position:
288 (13 in Wild Type peptide)
Alignment
Wild Type:
"PTDLVKRTVESMSAPEWEGAEQAPE
||||||||||||.||||||||||||
Mutant:
PTDLVKRTVESMCAPEWEGAEQAPE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) DENND3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay