Immunogenicity 4070
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
MROH5
Transcript ID
uc003ywi.2
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO
No TCR info found!
Full length protein sequence (1318 aa)
MDRQC
1
SERPY
6
SCTPT
11
GRVSS
16
AVSQN
21
SRISP
26
PVSTS
31
MKDSS
36
CMKVH
41
QDSAR
46
RDRWS
51
HPTTI
56
LLHKS
61
QSSQA
66
TLMLQ
71
EHRMF
76
MGEAY
81
SAATG
86
FKMLQ
91
DMNSA
96
DPFHL
101
KYIIK
106
KIKNM
111
AHGSP
116
KLVME
121
TIHDY
126
FIDNP
131
EISSR
136
HKFRL
141
FQTLE
146
MVIGA
151
SDVLE
156
ETWEK
161
TFTRL
166
ALENM
171
TKATE
176
LEDIY
181
QDAAS
186
NMLVA
191
ICRHS
196
WRVVA
201
QHLET
206
ELLTG
211
VFPHR
216
SLLYV
221
MGVLS
226
SSEEL
231
FSQED
236
KACWE
241
EQLIQ
246
MAIKS
251
VPFLS
256
TDVWS
261
KELLW
266
TLTTP
271
SWTQQ
276
EQSPE
281
KAFLF
286
TYYGL
291
ILQAE
296
KNGAT
301
VRRHL
306
QALLE
311
TSHQW
316
PKQRE
321
GMALT
326
LGLAA
331
TRHLD
336
DVWAV
341
LDQFG
346
RSRPI
351
RWSLP
356
SSSPK
361
NSEDL
366
RWKWA
371
SSTIL
376
LAYGQ
381
VAAKA
386
RAHIL
391
PWVDN
396
IVSRM
401
VFYFH
406
YSSWD
411
ETLKQ
416
SFLTA
421
TLMLM
426
GAVSR
431
SEGAH
436
SYEFF
441
QTSEL
446
LQCLM
451
VLMEK
456
EPQDT
461
LCTRS
466
RQQAM
471
HIASS
476
LCKLR
481
PPIDL
486
ERKSQ
491
LLSTC
496
FRSVF
501
ALPLL
506
DALEK
511
HTCLF
516
LEPPN
521
IQLWP
526
VARER
531
AGWTH
536
QGWGP
541
RAVLH
546
CSEHL
551
QSLYS
556
RTMEA
561
LDFML
566
QSLIM
571
QNPTA
576
DELHF
581
LLSHL
586
YIWLA
591
SEKAH
596
ERQRA
601
VHSCM
606
ILLKF
611
LNHNG
616
YLDPK
621
EDFKR
626
IGQLV
631
GILGM
636
LCQDP
641
DRATQ
646
RCSLE
651
GASHL
656
YQLLM
661
CHKTG
666
EALQA
671
ESQAP
676
KELSQ
681
AHSDG
686
APLWN
691
SRDQK
696
ATPLG
701
PQEMA
706
KNHIF
711
QLCSF
716
QVIKD
721
IMQQL
726
TLAEL
731
SDLIW
736
TAIDG
741
LGSTS
746
PFRVQ
751
AASEM
756
LLTAV
761
QEHGA
766
KLEIV
771
SSMAQ
776
AIRLR
781
LCSVH
786
IPQAK
791
EKTLH
796
AITLL
801
ARSHT
806
CELVA
811
TFLNI
816
SIPLD
821
SHTFQ
826
LWRAL
831
GAGQP
836
TSHLV
841
LTTLL
846
ACLQE
851
RPLPT
856
GASDS
861
SPCPK
866
EKTYL
871
RLLAA
876
MNMLH
881
ELQFA
886
REFKQ
891
AVQEG
896
YPKLF
901
LALLT
906
QMHYV
911
LELNL
916
PSEPQ
921
PKQQA
926
QEAAV
931
PSPQS
936
CSTSL
941
EALKS
946
LLSTT
951
GHWHD
956
FAHLE
961
LQGSW
966
ELFTT
971
IHTYP
976
KGVGL
981
LARAM
986
VQNHC
991
RQIPA
996
VLRQL
1001
LPSLQ
1006
SPQER
1011
ERKVA
1016
ILILT
1021
KFLYS
1026
PVLLE
1031
VLPKQ
1036
AALTV
1041
LAQGL
1046
HDPSP
1051
EVRVL
1056
SLQGL
1061
SNILF
1066
HPDKG
1071
SLLQG
1076
QLRPL
1081
LDGFF
1086
QSSDQ
1091
VIVCI
1096
MGTVS
1101
DTLHR
1106
LGAQG
1111
TGSQS
1116
LGVAI
1121
STRSF
1126
FNDER
1131
DGIRA
1136
AAMAL
1141
FGDLV
1146
AAMAD
1151
RELSG
1156
LRTQV
1161
HQSMV
1166
PLLLH
1171
LKDQC
1176
PAVAT
1181
QAKFT
1186
FYRCA
1191
VLLRW
1196
RLLHT
1201
LFCTL
1206
AWERG
1211
LSARH
1216
FLWTC
1221
LMTRS
1226
QEEFS
1231
IHLSQ
1236
ALSYL
1241
HSHSC
1246
HIKTW
1251
VTLFI
1256
GHTIC
1261
YHPQA
1266
VFQML
1271
NAVDT
1276
NLLFR
1281
TFEHL
1286
RSDPE
1291
PSIRE
1296
FATSQ
1301
LSFLQ
1306
KVSAR
1311
PKQ
1316
Mutation Information
DNA mutation:
None
Peptide Range:
192 ~ 216
Mut AA position:
204 (13 in Wild Type peptide)
Alignment
Wild Type:
"MLVAICRHSWRVVAQHLETELLTGV
||||||||||||.||||||||||||
Mutant:
MLVAICRHSWRVGAQHLETELLTGV"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) MROH5
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay