Immunogenicity 411
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PRRC2C
Transcript ID
None
HLA INFO
B*15:01
TCR INFO
No TCR info found!
Full length protein sequence (2903 aa)
MSEKS
1
GQSTK
6
AKDGK
11
KYATL
16
SLFNT
21
YKGKS
26
LETQK
31
TTVAA
36
RHGLQ
41
SLGKV
46
GISRR
51
MPPPA
56
NLPSL
61
KAENK
66
GNDPN
71
VNIVP
76
KDGTG
81
WASKQ
86
EQHEE
91
EKTPE
96
VPPAQ
101
PKPGV
106
AAPPE
111
VAPAP
116
KSWAS
121
NKQGG
126
QGDGI
131
QVNSQ
136
FQQEF
141
PSLQA
146
AGDQE
151
KKEKE
156
TNDDN
161
YGPGP
166
SLRPP
171
NVACW
176
RDGGK
181
AAGSP
186
SSSDQ
191
DEKLP
196
GQDES
201
TAGTS
206
EQNDI
211
LKVVE
216
KRIAC
221
GPPQA
226
KLNGQ
231
QAALA
236
SQYRA
241
MMPPY
246
MFQQY
251
PRMTY
256
PPLHG
261
PMRFP
266
PSLSE
271
TNKGL
276
RGRGP
281
PPSWA
286
SEPER
291
PSILS
296
ASELK
301
ELDKF
306
DNLDA
311
EADEG
316
WAGAQ
321
MEVDY
326
TEQLN
331
FSDDD
336
EQGSN
341
SPKEN
346
NSEDQ
351
GSKAS
356
ENNEN
361
KKETD
366
EVSNT
371
KSSSQ
376
IPAQP
381
SVAKV
386
PYGKG
391
PSFNQ
396
ERGTS
401
SHLPP
406
PPKLL
411
AQQHP
416
PPDRQ
421
AVPGR
426
PGPFP
431
SKQQV
436
ADEDE
441
IWKQR
446
RRQQS
451
EISAA
456
VERAR
461
KRREE
466
EERRM
471
EEQRK
476
AACAE
481
KLKRL
486
DEKLG
491
ILEKQ
496
PSPEE
501
IRERE
506
REKER
511
EREKE
516
LEKEQ
521
EQERE
526
KEREK
531
DRERQ
536
QEKEK
541
ELEKE
546
QEKQR
551
EMEKE
556
RKQEK
561
EKELE
566
RQKEK
571
EKELQ
576
KMKEQ
581
EKECE
586
LEKER
591
EKLEE
596
KIEPR
601
EPNLE
606
PMVEK
611
QESEN
616
SCNKE
621
EEPVF
626
TRQDS
631
NRSEK
636
EATPV
641
VHETE
646
PESGS
651
QPRPA
656
VLSGY
661
FKQFQ
666
KSLPP
671
RFQRQ
676
QEQMK
681
QQQWQ
686
QQQQQ
691
GVLPQ
696
TVPSQ
701
PSSST
706
VPPPP
711
HRPLY
716
QPMQP
721
HPQHL
726
ASMGF
731
DPRWL
736
MMQSY
741
MDPRM
746
MSGRP
751
AMDIP
756
PIHPG
761
MIPPK
766
PLMRR
771
DQMEG
776
SPNSS
781
ESFEH
786
IARSA
791
RDHAI
796
SLSEP
801
RMLWG
806
SDPYP
811
HAEPQ
816
QATTP
821
KATEE
826
PEDVR
831
SEAAL
836
DQEQI
841
TAAYS
846
VEHNQ
851
LEAHP
856
KADFI
861
RESSE
866
AQVQK
871
FLSRS
876
VEDVR
881
PHHTD
886
ANNQS
891
ACFEA
896
PDQKT
901
LSAPQ
906
EERIS
911
AVESQ
916
PSRKR
921
SVSHG
926
SNHTQ
931
KPDEQ
936
RSEPS
941
AGIPK
946
VTSRC
951
IDSKE
956
PIERP
961
EEKPK
966
KEGFI
971
RSSEG
976
PKPEK
981
VYKSK
986
SETRW
991
GPRPS
996
SNRRE
1001
EVNDR
1006
PVRRS
1011
GPIKK
1016
PVLRD
1021
MKEER
1026
EQRKE
1031
KEGEK
1036
AEKVT
1041
EKVVV
1046
KPEKT
1051
EKKDL
1056
PPPPP
1061
PPQPP
1066
APIQP
1071
QSVPP
1076
PIQPE
1081
AEKFP
1086
STETA
1091
TLAQK
1096
PSQDT
1101
EKPLE
1106
PVSTV
1111
QVEPA
1116
VKTVN
1121
QQTMA
1126
APVVK
1131
EEKQP
1136
EKVIS
1141
KDLVI
1146
ERPRP
1151
DSRPA
1156
VKKES
1161
TLPPR
1166
TYWKE
1171
ARERD
1176
WFPDQ
1181
GYRGR
1186
GRGEY
1191
YSRGR
1196
SYRGS
1201
YGGRG
1206
RGGRG
1211
HTRDY
1216
PQYRD
1221
NKPRA
1226
EHIPS
1231
GPLRQ
1236
REESE
1241
TRSES
1246
SDFEV
1251
VPKRR
1256
RQRGS
1261
ETDTD
1266
SEIHE
1271
SASDK
1276
DSLSK
1281
GKLPK
1286
REERP
1291
ENKKP
1296
VKPHS
1301
SFKPD
1306
NHVRI
1311
DNRLL
1316
EKPYV
1321
RDDDK
1326
AKPGF
1331
LPKGE
1336
PTRRG
1341
RGGTF
1346
RRGGR
1351
DPGGR
1356
PSRPS
1361
TLRRP
1366
AYRDN
1371
QWNPR
1376
QSEVP
1381
KPEDG
1386
EPPRR
1391
HEQFI
1396
PIAAD
1401
KRPPK
1406
FERKF
1411
DPARE
1416
RPRRQ
1421
RPTRP
1426
PRQDK
1431
PPRFR
1436
RLRER
1441
EAASK
1446
SNEVV
1451
AVPTN
1456
GTVNN
1461
VAQEP
1466
VNTLG
1471
DISGN
1476
KTPDL
1481
SNQNS
1486
SDQAN
1491
EEWET
1496
ASESS
1501
DFNER
1506
RERDE
1511
KKNAD
1516
LNAQT
1521
VVKVG
1526
ENVLP
1531
PKREI
1536
AKRSF
1541
SSQRP
1546
VDRQN
1551
RRGNN
1556
GPPKS
1561
GRNFS
1566
GPRNE
1571
RRSGP
1576
PSKSG
1581
KRGPF
1586
DDQPA
1591
GTTGV
1596
DLING
1601
SSAHH
1606
QEGVP
1611
NGTGQ
1616
KNSKD
1621
STGKK
1626
REDPK
1631
PGPKK
1636
PKEKV
1641
DALSQ
1646
FDLNN
1651
YASVV
1656
IIDDH
1661
PEVTV
1666
IEDPQ
1671
SNLND
1676
DGFTE
1681
VVSKK
1686
QQKRL
1691
QDEER
1696
RKKEE
1701
QVIQV
1706
WNKKN
1711
ANEKG
1716
RSQTS
1721
KLPPR
1726
FAKKQ
1731
ATGIQ
1736
QAQSS
1741
ASVPP
1746
LASAP
1751
LPPST
1756
SASVP
1761
ASTSA
1766
PLPAT
1771
LTPVP
1776
ASTSA
1781
PVPAS
1786
TLAPV
1791
LASTS
1796
APVPA
1801
SPLAP
1806
VSASA
1811
SVSAS
1816
VPAST
1821
SAAAI
1826
TSSSA
1831
PASAP
1836
APTPI
1841
LASVS
1846
TPASV
1851
TILAS
1856
ASIPI
1861
LASAL
1866
ASTSA
1871
PTPAP
1876
AASSP
1881
AAPVI
1886
TAPTI
1891
PASAP
1896
TASVP
1901
LAPAS
1906
ASAPA
1911
PAPTP
1916
VSAPN
1921
PAPPA
1926
PAQTQ
1931
AQTHK
1936
PVQNP
1941
LQTTS
1946
QSSKQ
1951
PPPSI
1956
RLPSA
1961
QTPNG
1966
TDYVA
1971
SGKSI
1976
QTPQS
1981
HGTLT
1986
AELWD
1991
NKVAP
1996
PAVLN
2001
DISKK
2006
LGPIS
2011
PPQPP
2016
SVSAW
2021
NKPLT
2026
SFGSA
2031
PSSEG
2036
AKNGQ
2041
ESGLE
2046
IGTDT
2051
IQFGA
2056
PASNG
2061
NENEV
2066
VPVLS
2071
EKSAD
2076
KIPEP
2081
KEQRQ
2086
KQPRA
2091
GPIKA
2096
QKLPD
2101
LSPVE
2106
NKEHK
2111
PGPIG
2116
KERSL
2121
KNRKV
2126
KDAQQ
2131
VEPEG
2136
QEKPS
2141
PATVR
2146
STDPV
2151
TTKET
2156
KAVSE
2161
MSTEI
2166
GTMIS
2171
VSSAE
2176
YGTNA
2181
KESVT
2186
DYTTP
2191
SSSLP
2196
NTVAT
2201
NNTKM
2206
EDTLV
2211
NNVPL
2216
PNTLP
2221
LPKRE
2226
TIQQS
2231
SSLTS
2236
VPPTT
2241
FSLTF
2246
KMESA
2251
RKAWE
2256
NSPNV
2261
REKGS
2266
PVTST
2271
APPIA
2276
TGVSS
2281
SASGP
2286
STANY
2291
NSFSS
2296
ASMPQ
2301
IPVAS
2306
VTPTA
2311
SLSGA
2316
GTYTT
2321
SSLST
2326
KSTTT
2331
SDPPN
2336
ICKVK
2341
PQQLQ
2346
TSSLP
2351
SASHF
2356
SQLSC
2361
MPSLI
2366
AQQQQ
2371
NPQVY
2376
VSQSA
2381
AAQIP
2386
AFYMD
2391
TSHLF
2396
NTQHA
2401
RLAPP
2406
SLAQQ
2411
QGFQP
2416
GLSQP
2421
TSVQQ
2426
IPIPI
2431
YAPLQ
2436
GQHQA
2441
QLSLG
2446
AGPAV
2451
SQAQE
2456
LFSSS
2461
LQPYR
2466
SQPAF
2471
MQSSL
2476
SQPSV
2481
VLSGT
2486
AIHNF
2491
PTVQH
2496
QELAK
2501
AQSGL
2506
AFQQT
2511
SNTQP
2516
IPILY
2521
EHQLG
2526
QASGL
2531
GGSQL
2536
IDTHL
2541
LQARA
2546
NLTQA
2551
SNLYS
2556
GQVQQ
2561
PGQTN
2566
FYNTA
2571
QSPSA
2576
LQQVN
2581
YGMVT
2586
VPLPA
2591
SQLSL
2596
PNFGS
2601
TGQPL
2606
IALPQ
2611
TLQPP
2616
LQHTT
2621
PQAQA
2626
QSLSR
2631
PAQVS
2636
QPFRG
2641
LIPAG
2646
TQHSM
2651
IATTG
2656
KMSEM
2661
ELKAF
2666
GSGID
2671
IKPGT
2676
PPIAG
2681
RSTTP
2686
TSSPF
2691
RATST
2696
SPNSQ
2701
SSKMN
2706
SIVYQ
2711
KQFQS
2716
APATV
2721
RMTQP
2726
FPTQF
2731
APQIL
2736
SQPNL
2741
VPPLV
2746
RAPHT
2751
NTFPA
2756
PVQRP
2761
PMALA
2766
SQMPP
2771
PLTTG
2776
LMSHA
2781
RLPHV
2786
ARGPC
2791
GSLSG
2796
VRGNQ
2801
AQAAL
2806
KAEQD
2811
MKAKQ
2816
RAEVL
2821
QSTQR
2826
FFSEQ
2831
QQSKQ
2836
IGGGK
2841
AQKVD
2846
SDSSK
2851
PPETL
2856
TDPPG
2861
VCQEK
2866
VEEKP
2871
PPAPS
2876
IATKP
2881
VRTGP
2886
IKPQA
2891
IKTEE
2896
TKS
2901
Mutation Information
DNA mutation:
None
Peptide Range:
2295 ~ 2319
Mut AA position:
2300 (6 in Wild Type peptide)
Alignment
Wild Type:
"-----YNSFSSASM-----------
|||||||.|
Mutant:
PSTANYNSFSSAPMPQIPVASVTPT"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) PRRC2C
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
None
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay