Immunogenicity 412

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
TEX2
Transcript ID
None
HLA INFO
A*66:01
TCR INFO

No TCR info found!

T cell Tumor cell A*66:01
sequence
Full length protein sequence (1134 aa)
MTSLY
1
GRHAE
6
KTTDM
11
PKPSA
16
PKVHV
21
QRSVS
26
RDTIA
31
IHFSA
36
SGEEE
41
EEEEE
46
EFREY
51
FEEGL
56
DDQSI
61
VTGLE
66
AKEDL
71
YLEPQ
76
VGHDP
81
AGPAA
86
SPVLA
91
DGLSV
96
SQAPA
101
ILPVS
106
KNTVK
111
LLESP
116
VPAAQ
121
VLSTV
126
PLAVS
131
PGSSS
136
SGPLA
141
SSPSV
146
SSLSE
151
QKTSS
156
SSPLS
161
SPSKS
166
PILSS
171
SASTS
176
TLSSA
181
KPFMS
186
LVKSL
191
STEVE
196
PKESP
201
HPARH
206
RHLMK
211
TLVKS
216
LSTDT
221
SRQES
226
DTVSY
231
KPPDS
236
KLNLH
241
LFKQF
246
TQPRN
251
TGGDS
256
KTAPS
261
SPLTS
266
PSDTR
271
SFFKV
276
PEMEA
281
KIEDT
286
KRRLS
291
EVIYE
296
PFQLL
301
SKIIG
306
EESGS
311
HRPKA
316
LSSSA
321
SELSN
326
LSSLN
331
GHLES
336
NNNYS
341
IKEEE
346
CDSEG
351
DGYGS
356
DSNIP
361
RSDHP
366
KSTGE
371
PTREI
376
ELKSS
381
QGSSL
386
KDLGL
391
KTSSL
396
VLEKC
401
SLSAL
406
VSKED
411
EEFCE
416
LYTED
421
FDLET
426
EGESK
431
VDKLS
436
DIPLK
441
PEVLA
446
EDGVV
451
LDSED
456
EVDSA
461
VQHPE
466
LPVKT
471
LGFFI
476
MCVYV
481
YLILP
486
LPHYV
491
SGLFL
496
GIGLG
501
FMTAV
506
CVIWF
511
FTPPS
516
AHKYH
521
KLHKN
526
LRHWN
531
TRSLD
536
IKEPE
541
ILKGW
546
MNEIY
551
NYDPE
556
TYHAT
561
LTHSV
566
FVRLE
571
GGTLR
576
LSKPN
581
KNISR
586
RASYN
591
EPKPE
596
VTYIS
601
QKIYD
606
LSDSK
611
IYLVP
616
KTLAR
621
KRIWN
626
KKYPI
631
CIELG
636
QQDDF
641
MSKAQ
646
TDKET
651
SEEKP
656
PAEGS
661
EDPKK
666
PPRPQ
671
EGTRS
676
SQRDQ
681
ILYLF
686
GRTGR
691
EKEEW
696
FRRFI
701
LASKL
706
KSEIK
711
KSSGV
716
SGGKP
721
APVFL
726
APGLL
731
PAHSR
736
HNSPS
741
GHLTH
746
SRSSS
751
KGSVE
756
EIMSQ
761
PKQKE
766
LAGSV
771
RQKML
776
LDYSV
781
YMGRC
786
VPQES
791
RSPQR
796
SPLQS
801
AESSP
806
TAGKK
811
LPEVP
816
PSEEE
821
EQEAW
826
VNALL
831
GRIFW
836
DFLGE
841
KYWSD
846
LVSKK
851
IQMKL
856
SKIKL
861
PYFMN
866
ELTLT
871
ELDMG
876
VAVPK
881
ILQAF
886
KPYVD
891
HQGLW
896
IDLEM
901
SYNGS
906
FLMTL
911
ETKMN
916
LTKLG
921
KEPLV
926
EALKV
931
GEIGK
936
EGCRP
941
RAFCL
946
ADSDE
951
ESSSA
956
GSSEE
961
DDAPE
966
PSGGD
971
KQLLP
976
GAEGY
981
VGGHR
986
TSKIM
991
RFVDK
996
ITKSK
1001
YFQKA
1006
TETEF
1011
IKKKI
1016
EEVSN
1021
TPLLL
1026
TVEVQ
1031
ECRGT
1036
LAVNI
1041
PPPPT
1046
DRVWY
1051
GFRKP
1056
PHVEL
1061
KARPK
1066
LGERE
1071
VTLVH
1076
VTDWI
1081
EKKLE
1086
QEFQK
1091
VFVMP
1096
NMDDV
1101
YITIM
1106
HSAMD
1111
PRSTS
1116
CLLKD
1121
PPVEA
1126
ADQP
1131
Mutation Information
DNA mutation:
None
Peptide Range:
206 ~ 233
Mut AA position:
207 (2 in Wild Type peptide)
Alignment
Wild Type:
"----------HPARHRHLM---------
|.|||||||
Mutant:
STEVEPKESPHLARHRHLMKTLVKSLST"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) TEX2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

peptide

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay